Prothrombin gene mutation

Last reviewed

🖨 Print for my doctorAdvocacy Hub →
Who is this for?
Show terms as
1FDA treatments1Specialists8Treatment centers1Financial resources

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
Report missing data

Overview

Prothrombin gene mutation is treated with 1 medication in our database, including ARGATROBAN. 1 of these has manufacturer assistance programs available to help reduce out-of-pocket costs. Medications are manufactured by Mitsubishi Tanabe. Patients and caregivers can find copay cards, patient assistance programs, and travel grants for Prothrombin gene mutation treatment below.

Inheritance

Autosomal dominant

Passed on from just one parent; each child has about a 50% chance of inheriting it

Age of Onset

Adult

Begins in adulthood (age 18 or older)

NORD ↗

FDA & Trial Timeline

2 events
Feb 2026Evaluation of a Preventive Therapeutic Strategy for Postpartum Venous Thromboembolism in Women With Genetic Risk Factor

Hospices Civils de Lyon

TrialNOT YET RECRUITING
Jan 2026A Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CITY-FXI in Healthy Adults and Adults With FV Leiden or Prothrombin G20210A Mutation

City Therapeutics — PHASE1

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

1 available

ARGATROBAN

Argatroban· Mitsubishi Tanabe

Detailed copay and financial assistance information is not publicly available for this medication at this time. Please consult your pharmacist or the manufacturer's official patient support program fo

No actively recruiting trials found for Prothrombin gene mutation at this time.

New trials open frequently. Follow this disease to get notified.

Search ClinicalTrials.gov ↗Join the Prothrombin gene mutation community →

Specialists

1 foundView all specialists →
AL
Aurélien LEBRETON
Specialist
PI on 3 active trials

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

1 grants

MySpark Generation Patient Support Services

Spark Therapeutics

Apply ↗

Community

Open Prothrombin gene mutationForum →

No community posts yet. Be the first to share your experience with Prothrombin gene mutation.

Start the conversation →

Latest news about Prothrombin gene mutation

Disease timeline:

New recruiting trial: A Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CITY-FXI in Healthy Adults and Adults With FV Leiden or Prothrombin G20210A Mutation

A new clinical trial is recruiting patients for Prothrombin gene mutation

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Prothrombin gene mutation

What is Prothrombin gene mutation?

Prothrombin gene mutation is treated with 1 medication in our database, including ARGATROBAN. 1 of these has manufacturer assistance programs available to help reduce out-of-pocket costs. Medications are manufactured by Mitsubishi Tanabe. Patients and caregivers can find copay cards, patient assistance programs, and travel grants for Prothrombin gene mutation treatment below.

How is Prothrombin gene mutation inherited?

Prothrombin gene mutation follows a autosomal dominant inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

At what age does Prothrombin gene mutation typically begin?

Typical onset of Prothrombin gene mutation is adult. Age of onset can vary across affected individuals.

Which specialists treat Prothrombin gene mutation?

1 specialists and care centers treating Prothrombin gene mutation are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.

What treatment and support options exist for Prothrombin gene mutation?

1 FDA-approved treatment are currently tracked on UniteRare for Prothrombin gene mutation. See the treatments and support programs sections for copay assistance, eligibility, and contact details.