Posterior extramedullary conus spinal cord lipoma

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Overview

Posterior extramedullary conus spinal cord lipoma is a rare type of spinal lipoma, which is a benign (non-cancerous) fatty growth that develops on the outside of the spinal cord near its lower end, called the conus medullaris. The term 'posterior' means the lipoma sits behind the spinal cord, and 'extramedullary' means it is located outside the spinal cord tissue itself rather than growing within it. This condition is a type of spinal dysraphism, meaning it is related to abnormal development of the spine and spinal cord during early fetal growth. This lipoma can press on or tether the spinal cord, which may lead to neurological problems over time. Symptoms can include lower back pain, weakness or numbness in the legs, difficulty walking, bladder or bowel control problems, and changes in foot shape or leg length. Some patients may have a visible lump, dimple, or patch of hair on the lower back. In some cases, the condition may be found incidentally on imaging done for other reasons, and the person may have few or no symptoms. Treatment typically involves monitoring with regular neurological exams and imaging. If symptoms develop or worsen, surgery may be recommended to remove or reduce the lipoma and untether the spinal cord. The goal of surgery is to prevent further neurological decline. Outcomes vary depending on the size and exact location of the lipoma and how early it is detected. Early diagnosis and careful follow-up with a neurosurgical team are important for the best possible outcomes.

Key symptoms:

Lower back painWeakness in the legsNumbness or tingling in the legs or feetDifficulty walking or changes in gaitBladder control problems such as incontinence or difficulty urinatingBowel control problems such as constipation or incontinenceFoot deformities such as high arches or clubfootDifference in leg length or leg sizeVisible lump or fatty mass on the lower backSkin dimple, hair patch, or birthmark on the lower backProgressive loss of sensation in the lower bodyMuscle wasting in the legsPain that worsens with activity or straining

Inheritance

Sporadic

Usually appears on its own, not inherited from a parent

Age of Onset

Variable

Can begin at different ages, from infancy through adulthood

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for Posterior extramedullary conus spinal cord lipoma.

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No actively recruiting trials found for Posterior extramedullary conus spinal cord lipoma at this time.

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No specialists are currently listed for Posterior extramedullary conus spinal cord lipoma.

View NORD Rare Disease Centers ↗Undiagnosed Disease Network ↗

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Posterior extramedullary conus spinal cord lipoma.

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Community

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Caregiver Resources

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Questions for your doctor

Bring these to your next appointment

  • Q1.How large is the lipoma and is it causing tethering of the spinal cord?,Do I (or my child) need surgery now, or can we safely monitor with regular imaging?,What are the risks and benefits of surgery for this specific case?,What is the chance of the spinal cord re-tethering after surgery?,How often should follow-up MRI scans and neurological exams be done?,What symptoms should prompt me to seek urgent medical attention?,Are there any activity restrictions I should be aware of?

Common questions about Posterior extramedullary conus spinal cord lipoma

What is Posterior extramedullary conus spinal cord lipoma?

Posterior extramedullary conus spinal cord lipoma is a rare type of spinal lipoma, which is a benign (non-cancerous) fatty growth that develops on the outside of the spinal cord near its lower end, called the conus medullaris. The term 'posterior' means the lipoma sits behind the spinal cord, and 'extramedullary' means it is located outside the spinal cord tissue itself rather than growing within it. This condition is a type of spinal dysraphism, meaning it is related to abnormal development of the spine and spinal cord during early fetal growth. This lipoma can press on or tether the spinal

How is Posterior extramedullary conus spinal cord lipoma inherited?

Posterior extramedullary conus spinal cord lipoma follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.