Pneumonia caused by Pseudomonas aeruginosa infection

Last reviewed

🖨 Print for my doctorAdvocacy Hub →
ORPHA:90066J15.1
Who is this for?
Show terms as
1FDA treatments1Active trials5Specialists8Treatment centers3Financial resources

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
Report missing data

Overview

Pseudomonas aeruginosa pneumonia is a serious lung infection caused by a bacterium called Pseudomonas aeruginosa. This germ is found widely in the environment — in soil, water, and even in hospitals — and it is known for being very hard to treat because it can resist many common antibiotics. While healthy people rarely get this infection, it can be life-threatening for people who are already sick, have weakened immune systems, or are on breathing machines (ventilators) in intensive care units. When Pseudomonas infects the lungs, it causes inflammation and fluid buildup that makes it very hard to breathe. The infection can spread quickly and damage lung tissue. People with conditions like cystic fibrosis, chronic obstructive pulmonary disease (COPD), HIV, cancer, or those who have had organ transplants are at much higher risk. Patients in hospitals — especially those on ventilators — are also very vulnerable. This type of hospital-acquired pneumonia is sometimes called ventilator-associated pneumonia (VAP). Symptoms include high fever, chills, a bad cough with thick or greenish mucus, chest pain, and serious difficulty breathing. Treatment requires strong antibiotics, often given through an IV, and sometimes combinations of drugs are needed because the bacteria can become resistant. Early diagnosis and fast treatment are critical to improving outcomes.

Key symptoms:

High fever and chillsSevere cough with thick, green, yellow, or bloody mucusShortness of breath or difficulty breathingChest pain, especially when breathing deeply or coughingRapid breathing or rapid heart rateLow oxygen levels in the bloodExtreme tiredness and weaknessConfusion or disorientation, especially in older adultsBluish tint to lips or fingertips (a sign of low oxygen)Loss of appetite and weight loss in prolonged illness

Age of Onset

Variable

Can begin at different ages, from infancy through adulthood

Orphanet ↗NORD ↗

FDA & Trial Timeline

2 events
Aug 2014Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis

University of Ulm

TrialRECRUITING
Dec 1997

TOBI: FDA approved

Management of cystic fibrosis patients with P.aeruginosa.

FDAcompleted

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

1 available

Cayston

aztreonam· Gilead Sciences, Inc.

indicated to improve respiratory symptoms in cystic fibrosis (CF) patients with Pseudomonas aeruginosa

Clinical Trials

1 recruitingView all trials with filters →
Other1 trial
Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis
Actively Recruiting
PI: Manfred Weiss, MD, MBA (University Ulm, University Hospital Ulm) · Sites: Ulm · Age: 1890 yrs

Specialists

5 foundView all specialists →
JP
Jean-Jacques Rouby, MD, PhD
Specialist
PI on 1 active trial
MM
Manfred Weiss, MD, MBA
Specialist
PI on 1 active trial
AB
Anne Sedlag, Biochemist
Specialist
PI on 1 active trial
DP
David Paterson, Professor
PITTSBURGH, PA
Specialist
PI on 2 active trials
VG
Violetta Georgescu
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Financial Resources

3 resources
Cayston(aztreonam)Gilead Sciences, Inc.

TOBRAMYCIN

Eli Lilly

Pseudomonas Pneumonia

Unverified — confirm before calling
copay card
Copay CardPatient Assistance
Accepting applications

TOBI

Mylan Specialty LP

TOBI — Contact Mylan Specialty LP

Unverified — confirm before calling
Patient Assistance
Manufacturer Program
Accepting applications

Travel Grants

No travel grants are currently matched to Pneumonia caused by Pseudomonas aeruginosa infection.

Search all travel grants →NORD Financial Assistance ↗

Community

Open Pneumonia caused by Pseudomonas aeruginosa infectionForum →

No community posts yet. Be the first to share your experience with Pneumonia caused by Pseudomonas aeruginosa infection.

Start the conversation →

Latest news about Pneumonia caused by Pseudomonas aeruginosa infection

Disease timeline:

New recruiting trial: Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis

A new clinical trial is recruiting patients for Pneumonia caused by Pseudomonas aeruginosa infection

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.Which antibiotic is being used to treat this infection, and how do we know it will work against this specific strain?,How long will treatment last, and will it be given in the hospital or can it be continued at home?,Is this a drug-resistant strain, and what does that mean for my treatment options?,What can we do to prevent this infection from coming back?,Are there any long-term effects on my lungs that I should watch for after recovery?,Should other family members or close contacts take any precautions?,If I have an underlying condition like cystic fibrosis or a weakened immune system, how does that change my treatment plan?

Common questions about Pneumonia caused by Pseudomonas aeruginosa infection

What is Pneumonia caused by Pseudomonas aeruginosa infection?

Pseudomonas aeruginosa pneumonia is a serious lung infection caused by a bacterium called Pseudomonas aeruginosa. This germ is found widely in the environment — in soil, water, and even in hospitals — and it is known for being very hard to treat because it can resist many common antibiotics. While healthy people rarely get this infection, it can be life-threatening for people who are already sick, have weakened immune systems, or are on breathing machines (ventilators) in intensive care units. When Pseudomonas infects the lungs, it causes inflammation and fluid buildup that makes it very hard

Are there clinical trials for Pneumonia caused by Pseudomonas aeruginosa infection?

Yes — 1 recruiting clinical trial is currently listed for Pneumonia caused by Pseudomonas aeruginosa infection on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Pneumonia caused by Pseudomonas aeruginosa infection?

5 specialists and care centers treating Pneumonia caused by Pseudomonas aeruginosa infection are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.

What treatment and support options exist for Pneumonia caused by Pseudomonas aeruginosa infection?

2 patient support programs are currently tracked on UniteRare for Pneumonia caused by Pseudomonas aeruginosa infection. See the treatments and support programs sections for copay assistance, eligibility, and contact details.