Plummer-Vinson syndrome

Plummer-Vinson syndrome (also called Patterson-Kelly syndrome or sideropenic dysphagia) is a rare condition that combines three main problems: difficulty swallowing, iron-deficiency anemia, and thin web-like growths of tissue in the upper part of the esophagus (the tube that carries food from your mouth to your stomach). These webs can partially block the esophagus, making it hard to swallow solid foods. The anemia means your blood is not carrying enough oxygen, which causes tiredness, weakness, and pale skin. The condition most often affects middle-aged women, though it can occur in anyone. Doctors believe it develops because of long-term, severe iron deficiency, though the exact cause is not fully understood. Other symptoms can include a sore, smooth tongue, cracked corners of the mouth, brittle nails, and an enlarged spleen in some cases. The good news is that Plummer-Vinson syndrome usually responds well to treatment. Iron supplementation can correct the anemia and may help the esophageal webs improve on their own. If the webs are causing significant swallowing problems, a doctor can gently stretch or break them open during an endoscopy procedure. With proper treatment, most people do very well. However, it is important to know that this condition has been linked to a higher risk of developing cancer in the throat or esophagus over time, so regular monitoring is recommended.

Bring these to your next appointment

• Q1.How long will I need to take iron supplements, and how will we know when my iron levels are back to normal?,Do my esophageal webs need to be treated with dilation, or can they improve with iron treatment alone?,What is my personal risk of developing throat or esophageal cancer, and how often should I be monitored?,Are there dietary changes I should make to help increase my iron levels naturally?,What symptoms should prompt me to seek urgent medical care?,Should I see any other specialists, such as a dietitian or an ENT doctor?,What is the expected timeline for my swallowing to improve with treatment?

Common questions about Plummer-Vinson syndrome