Overview
Pinnae fistula or cyst, also known as preauricular sinus, preauricular fistula, or preauricular pit, is a common congenital malformation resulting from incomplete or abnormal fusion of the auricular hillocks during embryonic development of the external ear. The condition presents as a small pit, sinus tract, or cyst located typically near the anterior margin of the ascending helix of the ear (pinna). It may be unilateral or bilateral and can occur as an isolated finding or, less commonly, as part of a broader syndrome such as branchio-oto-renal syndrome or other first and second branchial arch anomalies. Most individuals with preauricular sinuses are asymptomatic and the condition is discovered incidentally. However, the sinus tract can become a site of recurrent infection, leading to abscess formation, discharge of purulent or sebaceous material, pain, and swelling in the preauricular region. Repeated infections can cause scarring and chronic drainage. The condition primarily affects the skin and soft tissues surrounding the external ear. Treatment is generally not required for asymptomatic preauricular sinuses. When recurrent infections occur, acute episodes are managed with antibiotics and, if necessary, incision and drainage of abscesses. Definitive treatment involves complete surgical excision of the sinus tract and any associated cyst to prevent recurrence. Surgical excision is recommended after recurrent infections, as incomplete removal can lead to recurrence. Prognosis is excellent following complete excision. In cases where the preauricular sinus is associated with a syndromic condition, evaluation for associated anomalies, particularly renal and hearing abnormalities, may be warranted.
Variable
Can be inherited in different ways depending on the underlying gene
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for Pinnae fistula or cyst.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for Pinnae fistula or cyst at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →No specialists are currently listed for Pinnae fistula or cyst.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Pinnae fistula or cyst.
Community
No community posts yet. Be the first to share your experience with Pinnae fistula or cyst.
Start the conversation →Latest news about Pinnae fistula or cyst
No recent news articles for Pinnae fistula or cyst.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Common questions about Pinnae fistula or cyst
What is Pinnae fistula or cyst?
Pinnae fistula or cyst, also known as preauricular sinus, preauricular fistula, or preauricular pit, is a common congenital malformation resulting from incomplete or abnormal fusion of the auricular hillocks during embryonic development of the external ear. The condition presents as a small pit, sinus tract, or cyst located typically near the anterior margin of the ascending helix of the ear (pinna). It may be unilateral or bilateral and can occur as an isolated finding or, less commonly, as part of a broader syndrome such as branchio-oto-renal syndrome or other first and second branchial arch
At what age does Pinnae fistula or cyst typically begin?
Typical onset of Pinnae fistula or cyst is neonatal. Age of onset can vary across affected individuals.