Osteochondrosis of the tarsal bone

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Overview

Osteochondrosis of the tarsal bone is a condition that affects the bones in the foot, specifically the tarsal bones — the group of small bones that make up the back and middle part of your foot. In this condition, the blood supply to a tarsal bone is temporarily disrupted, which causes the bone tissue to break down and then slowly heal and reshape over time. The most well-known form is called Köhler's disease, which affects the navicular bone in the foot, and is most commonly seen in children. Another related form, Freiberg's disease (or Freiberg's infraction), affects the heads of the metatarsal bones near the toes and tends to occur in older children and teenagers. The main symptoms include pain, swelling, and tenderness in the foot, which can make walking difficult. Children may limp or avoid putting weight on the affected foot. The condition is usually diagnosed using X-rays, which can show changes in the shape and density of the affected bone. In most cases, especially in younger children, the bone heals on its own over time with rest and supportive care. Treatment focuses on relieving pain and protecting the foot while the bone recovers. Serious long-term problems are uncommon, especially when the condition is caught and managed early.

Also known as:

Key symptoms:

Pain in the middle or back of the footSwelling around the affected foot boneTenderness when pressing on the top of the footLimping or walking on the outer edge of the foot to avoid painStiffness in the foot, especially after restDifficulty walking or runningWarmth or redness over the affected areaReduced activity due to foot discomfort

Clinical phenotype terms (13)— hover any for plain English
Tarsal stipplingHP:0008131Flattening of the talar domeHP:0008144Abnormal tarsal ossificationHP:0008369Foot painHP:0025238Ankle painHP:0030840Tarsal sclerosisHP:0031051Antalgic gaitHP:0031955ChondritisHP:0100662Osteochondritis dissecansHP:0010886Juvenile aseptic necrosisHP:0100323
Inheritance

Multifactorial

Caused by a mix of several genes and environmental factors

Age of Onset

Juvenile

Begins in the teen years

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for Osteochondrosis of the tarsal bone.

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No actively recruiting trials found for Osteochondrosis of the tarsal bone at this time.

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No specialists are currently listed for Osteochondrosis of the tarsal bone.

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Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Osteochondrosis of the tarsal bone.

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Community

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Caregiver Resources

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Questions for your doctor

Bring these to your next appointment

  • Q1.Which specific tarsal bone is affected, and how severe is the damage based on the X-rays?,How long do you expect the healing process to take, and what signs should I watch for that things are improving?,Does my child need a cast, walking boot, or special insoles, and for how long?,What activities should my child avoid, and when can they return to sports or physical education?,Will this condition cause any permanent damage to the foot or affect my child's long-term mobility?,How often do we need follow-up X-rays or appointments to check on healing?,Are there any warning signs that should prompt me to bring my child in urgently before the next scheduled visit?

Common questions about Osteochondrosis of the tarsal bone

What is Osteochondrosis of the tarsal bone?

Osteochondrosis of the tarsal bone is a condition that affects the bones in the foot, specifically the tarsal bones — the group of small bones that make up the back and middle part of your foot. In this condition, the blood supply to a tarsal bone is temporarily disrupted, which causes the bone tissue to break down and then slowly heal and reshape over time. The most well-known form is called Köhler's disease, which affects the navicular bone in the foot, and is most commonly seen in children. Another related form, Freiberg's disease (or Freiberg's infraction), affects the heads of the metatar

How is Osteochondrosis of the tarsal bone inherited?

Osteochondrosis of the tarsal bone follows a multifactorial inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

At what age does Osteochondrosis of the tarsal bone typically begin?

Typical onset of Osteochondrosis of the tarsal bone is juvenile. Age of onset can vary across affected individuals.