OBSOLETE: Ulnar hemimelia, bilateral

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ORPHA:295073
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Overview

Ulnar hemimelia, bilateral, is a rare congenital limb condition in which the ulna bone — one of the two long bones in the forearm — is partially or completely absent in both arms. This condition is present at birth and results from abnormal limb development during pregnancy. Because the ulna plays an important role in forearm structure, wrist stability, and elbow function, its absence can lead to shortened forearms, limited range of motion at the elbow and wrist, bowing of the remaining forearm bone (the radius), and abnormalities of the hand and fingers on both sides. The severity can vary widely; some individuals may have only a small portion of the ulna missing, while others may lack the bone entirely. Associated hand abnormalities may include missing or fused fingers. This condition may occur in isolation or as part of a broader syndrome. Treatment is primarily supportive and may include orthopedic surgery, prosthetics, and occupational therapy to improve function and independence. Note: This Orphanet entry is marked as 'OBSOLETE,' meaning it may have been reclassified or merged into a broader diagnostic category. Patients and families should consult with a clinical geneticist or orthopedic specialist for the most current classification and management guidance.

Also known as:

Key symptoms:

Shortened forearms on both sidesMissing or underdeveloped ulna bone in both armsLimited elbow movementLimited wrist movementBowing of the forearmMissing or fused fingersUnstable wrist jointsAbnormal hand shapeDifficulty gripping or holding objectsUnequal arm length compared to the body

Inheritance

Variable

Can be inherited in different ways depending on the underlying gene

Age of Onset

Neonatal

Begins at or shortly after birth (first 4 weeks)

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for OBSOLETE: Ulnar hemimelia, bilateral.

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No actively recruiting trials found for OBSOLETE: Ulnar hemimelia, bilateral at this time.

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No specialists are currently listed for OBSOLETE: Ulnar hemimelia, bilateral.

View NORD Rare Disease Centers ↗Undiagnosed Disease Network ↗

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to OBSOLETE: Ulnar hemimelia, bilateral.

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Community

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Latest news about OBSOLETE: Ulnar hemimelia, bilateral

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Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.How severe is the ulna deficiency in each arm, and what does that mean for my child's function?,Is this condition isolated, or could it be part of a genetic syndrome?,What surgical options are available, and when is the best time for surgery?,Would my child benefit from prosthetic devices or assistive technology?,What kind of therapy will help my child develop the best possible hand and arm function?,Are there genetic tests we should consider for family planning purposes?,Can you connect us with other families or support groups for children with limb differences?

Common questions about OBSOLETE: Ulnar hemimelia, bilateral

What is OBSOLETE: Ulnar hemimelia, bilateral?

Ulnar hemimelia, bilateral, is a rare congenital limb condition in which the ulna bone — one of the two long bones in the forearm — is partially or completely absent in both arms. This condition is present at birth and results from abnormal limb development during pregnancy. Because the ulna plays an important role in forearm structure, wrist stability, and elbow function, its absence can lead to shortened forearms, limited range of motion at the elbow and wrist, bowing of the remaining forearm bone (the radius), and abnormalities of the hand and fingers on both sides. The severity can vary wi

At what age does OBSOLETE: Ulnar hemimelia, bilateral typically begin?

Typical onset of OBSOLETE: Ulnar hemimelia, bilateral is neonatal. Age of onset can vary across affected individuals.