Overview
Symbrachydactyly of hand and foot, unilateral, is a rare congenital (present at birth) limb malformation. This condition is now classified as 'OBSOLETE' in the Orphanet database, meaning it has been reclassified or merged into a broader or more specific diagnostic category. Symbrachydactyly itself refers to a condition where a baby is born with short, underdeveloped fingers or toes that may also be webbed or fused together. In this particular form, the condition affects both the hand and the foot on one side of the body only (unilateral). The fingers and toes on the affected side may be very short, stiff, or partially missing, sometimes with small skin nubs where fingers or toes would normally be. The bones within the digits are typically shortened or absent. This condition occurs during early fetal development when the limb buds are forming. It is generally not progressive, meaning it does not get worse over time. Treatment focuses on improving hand and foot function and may include surgery, physical therapy, and adaptive devices. Many children with symbrachydactyly adapt remarkably well and lead full, active lives. Because this entry is obsolete, patients and families should work with their medical team to determine the most current and accurate diagnostic classification for their condition.
Key symptoms:
Short or underdeveloped fingers on one handShort or underdeveloped toes on one footMissing fingers or toes on the affected sideWebbed or fused digitsSmall skin nubs where fingers or toes should beStiff finger or toe jointsReduced grip strength in the affected handDifficulty with fine motor tasksUneven hand or foot size compared to the other sideShortened bones in the affected hand or foot
Sporadic
Usually appears on its own, not inherited from a parent
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Symbrachydactyly of hand and foot, unilateral.
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Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Symbrachydactyly of hand and foot, unilateral.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Symbrachydactyly of hand and foot, unilateral.
Community
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Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
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Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.What is the current best diagnostic classification for my child's condition?,Would surgery improve hand or foot function, and what are the risks?,What type of therapy would benefit my child the most right now?,Are there any genetic tests we should consider to rule out related conditions?,How can we best support my child's development and self-esteem?,Are there adaptive devices or prosthetics that could help with daily tasks?,Should we see a specialized hand surgeon, and how do we find one?
Common questions about OBSOLETE: Symbrachydactyly of hand and foot, unilateral
What is OBSOLETE: Symbrachydactyly of hand and foot, unilateral?
Symbrachydactyly of hand and foot, unilateral, is a rare congenital (present at birth) limb malformation. This condition is now classified as 'OBSOLETE' in the Orphanet database, meaning it has been reclassified or merged into a broader or more specific diagnostic category. Symbrachydactyly itself refers to a condition where a baby is born with short, underdeveloped fingers or toes that may also be webbed or fused together. In this particular form, the condition affects both the hand and the foot on one side of the body only (unilateral). The fingers and toes on the affected side may be very s
How is OBSOLETE: Symbrachydactyly of hand and foot, unilateral inherited?
OBSOLETE: Symbrachydactyly of hand and foot, unilateral follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does OBSOLETE: Symbrachydactyly of hand and foot, unilateral typically begin?
Typical onset of OBSOLETE: Symbrachydactyly of hand and foot, unilateral is neonatal. Age of onset can vary across affected individuals.