OBSOLETE: Split foot, unilateral

Last reviewed

🖨 Print for my doctorAdvocacy Hub →
ORPHA:295124
Who is this for?
Show terms as
8Treatment centers

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
Report missing data

Overview

Split foot, unilateral (also called unilateral ectrodactyly or lobster claw foot on one side) is a rare congenital limb malformation in which one foot has missing central toes and a deep cleft that divides the front of the foot into two parts, giving it a claw-like appearance. The term 'OBSOLETE' in the Orphanet classification means this specific entry has been retired or merged into a broader category of split hand/foot malformations (ectrodactyly). In this condition, only one foot is affected, while the other foot appears normal. The condition is present at birth and results from abnormal development of the limb bud during early pregnancy. The severity can vary widely. Some people have a mild cleft with only minor toe abnormalities, while others may have significant missing bones and a deep split in the foot. Walking and balance may be affected depending on how much of the foot structure is altered. Many individuals adapt well, especially with supportive footwear or orthotics. In some cases, surgery can improve the shape and function of the foot. Split foot can occur as an isolated finding (meaning no other body parts are affected) or as part of a broader genetic syndrome. When it occurs on its own and on just one side, it may arise sporadically without a family history, though genetic factors can still play a role. Treatment focuses on improving function and comfort, and may involve orthopedic surgery, custom shoes, physical therapy, and ongoing monitoring during growth.

Key symptoms:

Deep cleft or split in the middle of one footMissing toes, especially the central toesFoot that looks like a lobster claw on one sideFused or webbed remaining toesAbnormally shaped foot bonesDifficulty fitting into standard shoesAltered walking pattern or gaitBalance difficultiesOne foot appearing normal while the other is affectedPossible mild leg length difference

Inheritance

Variable

Can be inherited in different ways depending on the underlying gene

Age of Onset

Neonatal

Begins at or shortly after birth (first 4 weeks)

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for OBSOLETE: Split foot, unilateral.

View clinical trials →

No actively recruiting trials found for OBSOLETE: Split foot, unilateral at this time.

New trials open frequently. Follow this disease to get notified.

Search ClinicalTrials.gov ↗Join the OBSOLETE: Split foot, unilateral community →

No specialists are currently listed for OBSOLETE: Split foot, unilateral.

View NORD Rare Disease Centers ↗Undiagnosed Disease Network ↗

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to OBSOLETE: Split foot, unilateral.

Search all travel grants →NORD Financial Assistance ↗

Community

Open OBSOLETE: Split foot, unilateralForum →

No community posts yet. Be the first to share your experience with OBSOLETE: Split foot, unilateral.

Start the conversation →

Latest news about OBSOLETE: Split foot, unilateral

No recent news articles for OBSOLETE: Split foot, unilateral.

Follow this condition to be notified when news becomes available.

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.Is my child's split foot isolated, or could it be part of a genetic syndrome?,Should we pursue genetic testing, and what would it tell us?,What surgical options are available, and when is the best time for surgery?,Will my child be able to walk and run normally?,What type of shoes or orthotics do you recommend?,How often should we schedule follow-up visits during growth?,Are there any risks that this could affect future children in our family?

Common questions about OBSOLETE: Split foot, unilateral

What is OBSOLETE: Split foot, unilateral?

Split foot, unilateral (also called unilateral ectrodactyly or lobster claw foot on one side) is a rare congenital limb malformation in which one foot has missing central toes and a deep cleft that divides the front of the foot into two parts, giving it a claw-like appearance. The term 'OBSOLETE' in the Orphanet classification means this specific entry has been retired or merged into a broader category of split hand/foot malformations (ectrodactyly). In this condition, only one foot is affected, while the other foot appears normal. The condition is present at birth and results from abnormal de

At what age does OBSOLETE: Split foot, unilateral typically begin?

Typical onset of OBSOLETE: Split foot, unilateral is neonatal. Age of onset can vary across affected individuals.