OBSOLETE: Split foot

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ORPHA:294994
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8Treatment centers

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UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Split foot, also known as ectrodactyly of the foot or lobster claw foot, is a congenital limb malformation present at birth. In this condition, one or more central toes and parts of the associated bones in the foot (metatarsals) are missing, creating a deep cleft or split in the middle of the foot. The foot may appear to have a V-shaped or claw-like appearance. The condition can affect one foot or both feet, and the severity varies widely from person to person. Some individuals have a mild cleft with only minor toe abnormalities, while others have a more pronounced split that significantly changes the shape and function of the foot. Split foot can occur as an isolated finding or as part of a broader syndrome that may also involve the hands (split hand-foot malformation) or other body systems. When it occurs in isolation, it may be caused by specific genetic mutations, though in some cases the cause remains unknown. Treatment focuses on improving function and comfort, and may include specially fitted shoes, orthotics, physical therapy, or reconstructive surgery. Many people with split foot lead active, fulfilling lives, especially with appropriate support and adaptive strategies. Note that this Orphanet entry (294994) is marked as obsolete, meaning the classification has been updated or merged into other related entries such as split hand-foot malformation.

Key symptoms:

Missing central toes at birthDeep cleft or split in the middle of the footV-shaped or claw-like appearance of the footMissing or shortened bones in the middle of the footFused toes on either side of the cleftDifficulty fitting into standard shoesAltered walking pattern or gaitFoot pain or discomfort with prolonged standingReduced foot widthPossible involvement of both feetPossible similar changes in the hands

Inheritance

Variable

Can be inherited in different ways depending on the underlying gene

Age of Onset

Neonatal

Begins at or shortly after birth (first 4 weeks)

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for OBSOLETE: Split foot.

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No actively recruiting trials found for OBSOLETE: Split foot at this time.

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No specialists are currently listed for OBSOLETE: Split foot.

View NORD Rare Disease Centers ↗Undiagnosed Disease Network ↗

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to OBSOLETE: Split foot.

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Community

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Latest news about OBSOLETE: Split foot

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Caregiver Resources

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Mental Health Support

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Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.Is my child's split foot an isolated condition or part of a broader syndrome?,Should we pursue genetic testing, and what would the results mean for our family?,Will my child need surgery, and if so, at what age is it best to operate?,What type of shoes or orthotics would be most helpful right now?,How will this condition affect my child's ability to walk, run, and play sports?,Are there physical therapy programs you recommend for children with this condition?,What is the chance that future children could also have this condition?

Common questions about OBSOLETE: Split foot

What is OBSOLETE: Split foot?

Split foot, also known as ectrodactyly of the foot or lobster claw foot, is a congenital limb malformation present at birth. In this condition, one or more central toes and parts of the associated bones in the foot (metatarsals) are missing, creating a deep cleft or split in the middle of the foot. The foot may appear to have a V-shaped or claw-like appearance. The condition can affect one foot or both feet, and the severity varies widely from person to person. Some individuals have a mild cleft with only minor toe abnormalities, while others have a more pronounced split that significantly cha

At what age does OBSOLETE: Split foot typically begin?

Typical onset of OBSOLETE: Split foot is neonatal. Age of onset can vary across affected individuals.