Overview
Preaxial polydactyly of toes (unilateral) is a congenital condition where a baby is born with one or more extra toes on the inner side (big toe side) of one foot only. The term 'preaxial' means the extra digit appears on the thumb or big toe side of the hand or foot, as opposed to the pinky side. 'Unilateral' means it affects only one foot rather than both. This condition is present at birth and is typically noticed right away during the newborn examination. It is important to note that this specific Orphanet entry (295175) is marked as 'OBSOLETE,' meaning it has been retired or merged into a broader classification of preaxial polydactyly. Patients with this condition may now be classified under more general categories of preaxial polydactyly or limb malformations. The extra toe can range from a small, poorly formed nub of soft tissue to a fully developed toe with its own bones and joints. In many cases, the condition is isolated, meaning the child is otherwise healthy with no other birth defects. However, in some cases, extra toes can be part of a broader genetic syndrome. Treatment usually involves surgical removal of the extra toe to improve foot function and allow comfortable shoe-wearing. Surgery is typically performed in infancy or early childhood. The outlook is generally excellent, and most children go on to walk and run normally after successful surgery and recovery.
Also known as:
Key symptoms:
Extra toe on the big toe side of one footVisible extra digit at birthWider-than-normal forefoot on the affected sideDifficulty fitting into shoesPossible abnormal alignment of the big toeDuplicated toenail on the affected sidePossible limited movement in the extra or adjacent toe
Variable
Can be inherited in different ways depending on the underlying gene
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Preaxial polydactyly of toes, unilateral.
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Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Preaxial polydactyly of toes, unilateral.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Preaxial polydactyly of toes, unilateral.
Community
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Caregiver Resources
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Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Is my child's extra toe an isolated finding, or could it be part of a genetic syndrome?,What does the X-ray show about the bone structure of the extra toe?,What is the best age for surgery in my child's case?,Which toe will be removed, and how will the surgeon decide?,What are the risks of surgery, and what is the expected recovery time?,Will my child need any follow-up care as they grow?,Should genetic testing be done for our family?
Common questions about OBSOLETE: Preaxial polydactyly of toes, unilateral
What is OBSOLETE: Preaxial polydactyly of toes, unilateral?
Preaxial polydactyly of toes (unilateral) is a congenital condition where a baby is born with one or more extra toes on the inner side (big toe side) of one foot only. The term 'preaxial' means the extra digit appears on the thumb or big toe side of the hand or foot, as opposed to the pinky side. 'Unilateral' means it affects only one foot rather than both. This condition is present at birth and is typically noticed right away during the newborn examination. It is important to note that this specific Orphanet entry (295175) is marked as 'OBSOLETE,' meaning it has been retired or merged into a
At what age does OBSOLETE: Preaxial polydactyly of toes, unilateral typically begin?
Typical onset of OBSOLETE: Preaxial polydactyly of toes, unilateral is neonatal. Age of onset can vary across affected individuals.