Overview
Preaxial polydactyly of toes is a congenital (present at birth) condition in which a baby is born with an extra toe on the inner side of the foot, near the big toe. The term 'preaxial' refers to the thumb or big toe side of the hand or foot. This means the extra digit appears on the side closest to the big toe rather than the little toe side. It is important to note that this specific Orphanet entry (295006) is labeled as 'OBSOLETE,' meaning it has been retired or merged into a broader or updated classification of preaxial polydactyly. Patients and families searching for this condition may now find it classified under broader terms such as 'preaxial polydactyly' or specific subtypes of toe polydactyly. Polydactyly of the toes is one of the more common congenital limb differences. The extra toe may be fully formed with bones, joints, and a nail, or it may be a small, soft tissue nub without a complete bone structure. In many cases, the condition affects only one foot, but it can occur on both feet. It can appear as an isolated finding (meaning no other health problems are present) or as part of a broader genetic syndrome that affects other parts of the body. Treatment typically involves surgical removal of the extra toe, usually performed in early childhood. The surgery aims to create a foot that functions well and fits comfortably in shoes. Most children who undergo surgery have excellent outcomes and go on to walk, run, and play normally. When preaxial polydactyly of the toes occurs as part of a syndrome, additional medical evaluations and treatments may be needed depending on the other features involved.
Also known as:
Key symptoms:
Extra toe on the inner (big toe) side of the footWider-than-normal forefootDuplicated big toe or a toe next to the big toeDifficulty fitting into shoesThe extra toe may be fully formed or partially developedThe extra toe may be attached by skin only or have its own bonePossible abnormal alignment of the big toePossible cosmetic concern about foot appearance
Variable
Can be inherited in different ways depending on the underlying gene
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Preaxial polydactyly of toes.
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Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Preaxial polydactyly of toes.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Preaxial polydactyly of toes.
Community
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Caregiver Resources
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Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Is my child's extra toe an isolated finding, or could it be part of a genetic syndrome?,Should my child have genetic testing?,What is the best age for surgery, and what does the surgery involve?,What are the risks of surgery, and what outcomes can we expect?,Will my child be able to walk, run, and play sports normally after surgery?,Is there a chance this could happen again in future pregnancies?,How often will follow-up visits be needed after surgery?
Common questions about OBSOLETE: Preaxial polydactyly of toes
What is OBSOLETE: Preaxial polydactyly of toes?
Preaxial polydactyly of toes is a congenital (present at birth) condition in which a baby is born with an extra toe on the inner side of the foot, near the big toe. The term 'preaxial' refers to the thumb or big toe side of the hand or foot. This means the extra digit appears on the side closest to the big toe rather than the little toe side. It is important to note that this specific Orphanet entry (295006) is labeled as 'OBSOLETE,' meaning it has been retired or merged into a broader or updated classification of preaxial polydactyly. Patients and families searching for this condition may now
At what age does OBSOLETE: Preaxial polydactyly of toes typically begin?
Typical onset of OBSOLETE: Preaxial polydactyly of toes is neonatal. Age of onset can vary across affected individuals.