Overview
This entry, listed under Orphanet code 206606, is classified as 'OBSOLETE' and was previously used to describe conditions involving muscle weakness and/or chronic muscle pain that did not fit neatly into other specific diagnostic categories. Because this classification is no longer actively used in current medical databases, it served more as a broad grouping term rather than a single well-defined disease. Patients who were once categorized under this label may have conditions such as chronic myalgia, non-specific myopathy, fibromyalgia, or other neuromuscular disorders that cause ongoing muscle weakness or pain. Muscle weakness can range from mild difficulty with everyday tasks like climbing stairs or lifting objects to more severe forms that affect walking or breathing. Chronic muscle pain may be constant or come and go, and it can significantly affect quality of life. Because this is an umbrella term rather than a specific diagnosis, the underlying cause varies widely from person to person. Some cases may be related to inflammatory conditions, metabolic problems, genetic neuromuscular diseases, or other systemic illnesses. If you or a loved one was previously given this classification, it is important to work with your medical team to obtain a more specific and up-to-date diagnosis. Modern genetic testing, advanced imaging, muscle biopsies, and blood tests can now identify many conditions that were previously grouped under broad categories like this one. A more precise diagnosis can open the door to targeted treatments and better management strategies.
Key symptoms:
Muscle weakness in arms or legsChronic muscle pain or achingFatigue or low energyDifficulty climbing stairsTrouble lifting objectsMuscle stiffnessMuscle crampsReduced exercise toleranceDifficulty with fine motor tasks like buttoning clothesGeneral body soreness
Variable
Can be inherited in different ways depending on the underlying gene
Variable
Can begin at different ages, from infancy through adulthood
FDA & Trial Timeline
3 eventsIstanbul University — NA
Beth Israel Deaconess Medical Center
Karolinska Institutet — NA
Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Other muscle weakness and/or chronic muscle pain.
3 clinical trialsare actively recruiting — trials can provide access to cutting-edge therapies.
View clinical trials →Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Other muscle weakness and/or chronic muscle pain.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Other muscle weakness and/or chronic muscle pain.
Community
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Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Has a specific underlying cause for my muscle weakness or pain been identified, or do I need further testing?,Would genetic testing help clarify my diagnosis?,What type of physical therapy or exercise program would be safe and beneficial for me?,Are there any medications that could help manage my symptoms more effectively?,Should I be referred to a neuromuscular specialist or other subspecialist?,Are there any clinical trials or new treatments I should know about?,What warning signs should prompt me to seek emergency care?
Common questions about OBSOLETE: Other muscle weakness and/or chronic muscle pain
What is OBSOLETE: Other muscle weakness and/or chronic muscle pain?
This entry, listed under Orphanet code 206606, is classified as 'OBSOLETE' and was previously used to describe conditions involving muscle weakness and/or chronic muscle pain that did not fit neatly into other specific diagnostic categories. Because this classification is no longer actively used in current medical databases, it served more as a broad grouping term rather than a single well-defined disease. Patients who were once categorized under this label may have conditions such as chronic myalgia, non-specific myopathy, fibromyalgia, or other neuromuscular disorders that cause ongoing musc
Are there clinical trials for OBSOLETE: Other muscle weakness and/or chronic muscle pain?
Yes — 3 recruiting clinical trials are currently listed for OBSOLETE: Other muscle weakness and/or chronic muscle pain on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.