Overview
Natal teeth-intestinal pseudoobstruction-patent ductus syndrome is an extremely rare condition that was previously listed in medical databases but has since been marked as obsolete, meaning it may have been reclassified, merged with another diagnosis, or found to be part of a broader syndrome. The condition was originally described as a combination of three main features: natal teeth (teeth present at birth), intestinal pseudoobstruction (a condition where the intestines cannot push food through properly, even though there is no physical blockage), and patent ductus arteriosus (a heart defect where a blood vessel that normally closes after birth remains open). Babies born with this combination of problems would typically show feeding difficulties, abdominal bloating, vomiting, and heart-related symptoms from birth. Because this entry is now considered obsolete in the Orphanet classification system, patients and families who were previously given this diagnosis should work with their medical team to determine whether a more current or accurate diagnosis applies to their situation. Treatment would have been directed at managing each individual symptom, including surgical or medical management of the heart defect, nutritional support for intestinal problems, and dental care for natal teeth.
Key symptoms:
Teeth present at birth (natal teeth)Severe abdominal bloatingVomitingInability of the intestines to move food properly (pseudoobstruction)Constipation or inability to pass stoolFeeding difficulties in newbornsHeart murmur from an open blood vessel (patent ductus arteriosus)Poor weight gain and failure to thriveBreathing difficulties related to the heart defectAbdominal pain or discomfort
Autosomal recessive
Passed on when both parents carry the same gene change; often skips generations
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome.
Community
No community posts yet. Be the first to share your experience with OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome.
Start the conversation →Latest news about OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome
No recent news articles for OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Since this diagnosis is now considered obsolete, is there a more current or accurate diagnosis for my child's condition?,Would whole exome or whole genome sequencing help identify the specific genetic cause?,What is the best approach to managing the intestinal pseudoobstruction long-term?,Does my child's heart defect need surgical treatment, or can it be managed with medication?,What are the risks and benefits of long-term intravenous nutrition if my child cannot eat normally?,Are there any clinical trials or research studies that might be relevant to my child's condition?,What is the chance that future children could be affected if this is a genetic condition?
Common questions about OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome
What is OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome?
Natal teeth-intestinal pseudoobstruction-patent ductus syndrome is an extremely rare condition that was previously listed in medical databases but has since been marked as obsolete, meaning it may have been reclassified, merged with another diagnosis, or found to be part of a broader syndrome. The condition was originally described as a combination of three main features: natal teeth (teeth present at birth), intestinal pseudoobstruction (a condition where the intestines cannot push food through properly, even though there is no physical blockage), and patent ductus arteriosus (a heart defect
How is OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome inherited?
OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome follows a autosomal recessive inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome typically begin?
Typical onset of OBSOLETE: Natal teeth-intestinal pseudoobstruction-patent ductus syndrome is neonatal. Age of onset can vary across affected individuals.