OBSOLETE: Microscopic colitis

Microscopic colitis is a condition that causes inflammation in the large intestine (colon). The name comes from the fact that the inflammation can only be seen under a microscope — the colon looks completely normal during a colonoscopy. There are two main types: collagenous colitis, where a thick band of protein builds up in the colon lining, and lymphocytic colitis, where too many white blood cells collect in the colon tissue. Both types cause very similar symptoms. The main symptom is chronic, watery diarrhea that can be quite severe. People may have many loose bowel movements per day, often with cramping, bloating, and an urgent need to use the bathroom. Fatigue, mild weight loss, and nausea are also common. Symptoms can come and go over time. It is worth noting that Orphanet has marked this entry as 'obsolete,' meaning it has been reorganized or reclassified in their rare disease database. The two subtypes — collagenous colitis and lymphocytic colitis — are now typically listed separately. Treatment usually involves stopping medications that may trigger the condition, dietary changes, and anti-inflammatory drugs such as budesonide, which is commonly used and well-studied for this condition.

Bring these to your next appointment

• Q1.Which type of microscopic colitis do I have — collagenous or lymphocytic — and does it change my treatment?,Are any of my current medications likely causing or worsening my symptoms?,How long will I need to take budesonide, and what are the risks of long-term use?,What dietary changes might help reduce my symptoms?,How will we know if my treatment is working, and what is the plan if it does not?,What are the chances my symptoms will come back after treatment, and what should I do if they do?,Are there any clinical trials or newer treatments I should know about?

Common questions about OBSOLETE: Microscopic colitis