Overview
Low birth weight-dwarfism-dysgammaglobulinemia syndrome is an extremely rare condition that has been described in medical literature but is now considered an obsolete diagnostic term, meaning it is no longer recognized as a distinct disease entity in current medical classifications. Historically, this condition was characterized by a combination of very low birth weight, short stature (dwarfism), and problems with the immune system, specifically abnormal levels of immunoglobulins (antibodies) in the blood, known as dysgammaglobulinemia. The immune system abnormality meant that affected individuals had difficulty fighting off infections. Babies born with this condition were notably small and continued to grow poorly after birth. Because this diagnosis is now obsolete, it is likely that patients who were once given this label would today be reclassified under more specific and better-understood genetic or immunological conditions. If you or a family member has been given this diagnosis in the past, it is strongly recommended to seek a modern genetic evaluation to determine a more precise and current diagnosis, which can guide appropriate treatment and management strategies.
Also known as:
Key symptoms:
Very low birth weightShort stature or dwarfismAbnormal antibody levels in the bloodFrequent or severe infectionsPoor growth after birthFailure to thrive in infancyDelayed physical development
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome.
Community
No community posts yet. Be the first to share your experience with OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome.
Start the conversation →Latest news about OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome
No recent news articles for OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Is this diagnosis still considered valid, or should we pursue updated genetic testing to find a more specific diagnosis?,What type of genetic testing would you recommend to better understand my child's condition?,How severe is the immune deficiency, and does my child need immunoglobulin replacement therapy?,Are there specific infections or exposures we should be especially careful about?,Should my child see a pediatric endocrinologist for growth evaluation and possible growth hormone therapy?,Are there any clinical trials or new treatments that might be relevant?,What is the long-term outlook for my child's growth and immune function?
Common questions about OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome
What is OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome?
Low birth weight-dwarfism-dysgammaglobulinemia syndrome is an extremely rare condition that has been described in medical literature but is now considered an obsolete diagnostic term, meaning it is no longer recognized as a distinct disease entity in current medical classifications. Historically, this condition was characterized by a combination of very low birth weight, short stature (dwarfism), and problems with the immune system, specifically abnormal levels of immunoglobulins (antibodies) in the blood, known as dysgammaglobulinemia. The immune system abnormality meant that affected individ
At what age does OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome typically begin?
Typical onset of OBSOLETE: Low birth weight-dwarfism-dysgammaglobulinemia syndrome is neonatal. Age of onset can vary across affected individuals.