Overview
HIV-related cervical cancer, sometimes called AIDS-related cervical cancer or HIV-associated cervical cancer, is a type of cancer of the cervix (the lower part of the uterus that connects to the vagina) that occurs in people living with HIV. It is listed as an AIDS-defining illness, meaning its diagnosis in someone with HIV can indicate that their immune system has been severely weakened. This condition is now considered an obsolete classification in some medical coding systems, as cervical cancer in people with HIV is increasingly managed under broader cervical cancer and HIV care guidelines. Cervical cancer in people with HIV is almost always caused by persistent infection with high-risk strains of human papillomavirus (HPV), particularly HPV types 16 and 18. Because HIV weakens the immune system, the body has a harder time clearing HPV infections, which makes it easier for abnormal cervical cells to develop into cancer. Symptoms can include unusual vaginal bleeding (especially after sex or between periods), pelvic pain, unusual vaginal discharge, and pain during sex. Treatment depends on the stage of cancer and includes surgery, radiation therapy, chemotherapy, and targeted therapies. Antiretroviral therapy (ART) to control HIV is also a critical part of care, as keeping the immune system as strong as possible improves outcomes. With regular screening and early detection, this cancer is often preventable or caught at a treatable stage.
Key symptoms:
Unusual vaginal bleeding, such as bleeding after sex, between periods, or after menopausePelvic pain or pressurePain during sexual intercourseUnusual or foul-smelling vaginal dischargeHeavier or longer menstrual periods than usualSwelling in the legsDifficulty urinating or blood in the urineBack or leg painUnexplained weight lossFatigue and general weakness
Adult
Begins in adulthood (age 18 or older)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: HIV-related cervical cancer.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for OBSOLETE: HIV-related cervical cancer at this time.
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Specialists
View all specialists →No specialists are currently listed for OBSOLETE: HIV-related cervical cancer.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: HIV-related cervical cancer.
Community
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Start the conversation →Latest news about OBSOLETE: HIV-related cervical cancer
1 articlesCaregiver Resources
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Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.What stage is my cervical cancer, and what does that mean for my treatment options?,How will my HIV status and CD4 count affect my cancer treatment plan?,Should I change or adjust my antiretroviral therapy during cancer treatment?,Am I eligible for immunotherapy or targeted therapy, and how do these interact with HIV?,How often will I need monitoring for both my HIV and my cancer going forward?,Are there clinical trials I should consider for HIV-related cervical cancer?,What support services are available to help me manage both conditions at the same time?
Common questions about OBSOLETE: HIV-related cervical cancer
What is OBSOLETE: HIV-related cervical cancer?
HIV-related cervical cancer, sometimes called AIDS-related cervical cancer or HIV-associated cervical cancer, is a type of cancer of the cervix (the lower part of the uterus that connects to the vagina) that occurs in people living with HIV. It is listed as an AIDS-defining illness, meaning its diagnosis in someone with HIV can indicate that their immune system has been severely weakened. This condition is now considered an obsolete classification in some medical coding systems, as cervical cancer in people with HIV is increasingly managed under broader cervical cancer and HIV care guidelines.
At what age does OBSOLETE: HIV-related cervical cancer typically begin?
Typical onset of OBSOLETE: HIV-related cervical cancer is adult. Age of onset can vary across affected individuals.