Overview
Gastric neuroendocrine tumor type 4 (also sometimes called type 4 gastric NET or sporadic gastric carcinoid type 4) is a rare and aggressive form of stomach tumor that starts in the hormone-producing cells of the stomach lining. Unlike the other three types of gastric neuroendocrine tumors, type 4 does not develop because of high levels of a hormone called gastrin. Instead, it arises on its own, without a clear hormonal trigger, and tends to behave more like a typical stomach cancer. It is worth noting that this classification has been marked as 'obsolete' in some medical databases, meaning experts have updated how they categorize and name these tumors over time. You may see it referred to under newer classification systems for gastric neuroendocrine neoplasms. This type of tumor can grow quickly and spread to other parts of the body, including nearby lymph nodes and the liver. Because it often does not cause obvious symptoms early on, it is frequently found at an advanced stage. Symptoms can include stomach pain, nausea, weight loss, and bleeding in the digestive tract. Treatment usually involves surgery when possible, along with chemotherapy or targeted therapies. The overall outlook depends heavily on how far the tumor has spread at the time of diagnosis, and early detection greatly improves the chances of successful treatment.
Also known as:
Key symptoms:
Stomach pain or discomfortNausea and vomitingUnintended weight lossLoss of appetiteFeeling full quickly after eatingBlood in the stool or black, tarry stoolsFatigue and weaknessAnemia (low red blood cell count)Swelling in the abdomenJaundice (yellowing of the skin or eyes) if the liver is affected
Sporadic
Usually appears on its own, not inherited from a parent
Adult
Begins in adulthood (age 18 or older)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Gastric neuroendocrine tumor type 4.
View clinical trials →Clinical Trials
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Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Gastric neuroendocrine tumor type 4.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Gastric neuroendocrine tumor type 4.
Community
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Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
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Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.What stage is my tumor, and has it spread to other organs?,What treatment options are available for my specific situation, and what are the goals of treatment?,Am I a candidate for surgery, and what would that involve?,Are there any clinical trials I might be eligible for?,What imaging and blood tests will I need for ongoing monitoring, and how often?,Should I be seen at a specialized neuroendocrine tumor center?,What support services are available to help me and my family cope with this diagnosis?
Common questions about OBSOLETE: Gastric neuroendocrine tumor type 4
What is OBSOLETE: Gastric neuroendocrine tumor type 4?
Gastric neuroendocrine tumor type 4 (also sometimes called type 4 gastric NET or sporadic gastric carcinoid type 4) is a rare and aggressive form of stomach tumor that starts in the hormone-producing cells of the stomach lining. Unlike the other three types of gastric neuroendocrine tumors, type 4 does not develop because of high levels of a hormone called gastrin. Instead, it arises on its own, without a clear hormonal trigger, and tends to behave more like a typical stomach cancer. It is worth noting that this classification has been marked as 'obsolete' in some medical databases, meaning ex
How is OBSOLETE: Gastric neuroendocrine tumor type 4 inherited?
OBSOLETE: Gastric neuroendocrine tumor type 4 follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does OBSOLETE: Gastric neuroendocrine tumor type 4 typically begin?
Typical onset of OBSOLETE: Gastric neuroendocrine tumor type 4 is adult. Age of onset can vary across affected individuals.