Overview
Gastric neuroendocrine tumor type 2 (also called gastric NET type 2, or type 2 gastric carcinoid) is a rare type of stomach tumor that grows from special hormone-producing cells in the lining of the stomach. This condition is now considered an outdated or 'obsolete' classification in some medical coding systems, as experts have refined how these tumors are categorized. Type 2 gastric neuroendocrine tumors are closely linked to a condition called Zollinger-Ellison syndrome (ZES) combined with multiple endocrine neoplasia type 1 (MEN1), a genetic disorder that causes tumors in several hormone-producing glands. These tumors develop because too much gastrin — a hormone that tells the stomach to make acid — is produced by a separate tumor called a gastrinoma. This overload of gastrin causes the stomach's hormone cells to grow out of control, forming multiple small tumors. Symptoms often include stomach pain, acid reflux, diarrhea, and ulcers. Unlike some other stomach tumors, type 2 gastric NETs are usually slow-growing, but they can sometimes spread to other parts of the body. Treatment focuses on controlling the underlying cause — especially the gastrinoma and the excess gastrin — using medications like proton pump inhibitors and somatostatin analogs, as well as surgery when possible. Because this condition is tied to MEN1, a genetic syndrome, other family members may also be at risk and should be evaluated.
Also known as:
Key symptoms:
Stomach pain or crampingSevere acid reflux or heartburnChronic diarrheaStomach ulcers that keep coming backNausea and vomitingUnintended weight lossFeeling full quickly when eatingGastrointestinal bleeding (blood in stool or vomiting blood)FatigueSymptoms related to MEN1 such as kidney stones or low blood sugar
Autosomal dominant
Passed on from just one parent; each child has about a 50% chance of inheriting it
Adult
Begins in adulthood (age 18 or older)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Gastric neuroendocrine tumor type 2.
View clinical trials →Clinical Trials
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Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Gastric neuroendocrine tumor type 2.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Gastric neuroendocrine tumor type 2.
Community
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Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Is my tumor related to MEN1, and should my family members be tested for the MEN1 gene mutation?,What is the stage of my tumor, and has it spread anywhere in my body?,What treatment do you recommend first — medication, endoscopy, or surgery — and why?,How often will I need imaging and blood tests to monitor my condition?,Are there clinical trials available for my type of tumor?,What symptoms should prompt me to seek emergency care?,Should I see a specialist at a dedicated neuroendocrine tumor center?
Common questions about OBSOLETE: Gastric neuroendocrine tumor type 2
What is OBSOLETE: Gastric neuroendocrine tumor type 2?
Gastric neuroendocrine tumor type 2 (also called gastric NET type 2, or type 2 gastric carcinoid) is a rare type of stomach tumor that grows from special hormone-producing cells in the lining of the stomach. This condition is now considered an outdated or 'obsolete' classification in some medical coding systems, as experts have refined how these tumors are categorized. Type 2 gastric neuroendocrine tumors are closely linked to a condition called Zollinger-Ellison syndrome (ZES) combined with multiple endocrine neoplasia type 1 (MEN1), a genetic disorder that causes tumors in several hormone-pr
How is OBSOLETE: Gastric neuroendocrine tumor type 2 inherited?
OBSOLETE: Gastric neuroendocrine tumor type 2 follows a autosomal dominant inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does OBSOLETE: Gastric neuroendocrine tumor type 2 typically begin?
Typical onset of OBSOLETE: Gastric neuroendocrine tumor type 2 is adult. Age of onset can vary across affected individuals.