OBSOLETE: Gastric neuroendocrine tumor type 1

Gastric neuroendocrine tumor type 1 (also called gastric NET type 1, type 1 gastric carcinoid, or ECL-cell carcinoid type 1) is a rare, slow-growing tumor that forms in the stomach lining. These tumors grow from special hormone-producing cells called enterochromaffin-like (ECL) cells. Type 1 is the most common of the three types of gastric neuroendocrine tumors, making up about 70-80% of all gastric NETs. This type almost always develops in people who have a condition called chronic atrophic gastritis (often caused by an autoimmune process), which leads to very low stomach acid and high levels of a hormone called gastrin. Too much gastrin over a long time causes ECL cells to grow out of control, eventually forming small tumors. These tumors are usually small, multiple, and found in the upper part of the stomach. Most people with gastric NET type 1 have mild or no symptoms at first. Some may notice stomach discomfort, nausea, or signs of anemia. The good news is that type 1 gastric NETs are generally considered low-risk and rarely spread to other parts of the body. Treatment often involves regular monitoring with endoscopy, and in some cases, removal of the tumors through endoscopy or medication to lower gastrin levels. The overall outlook is very favorable compared to other stomach cancers.

Bring these to your next appointment

• Q1.How often do I need endoscopy, and what are you looking for each time?,Do my tumors need to be removed now, or can we monitor them?,Should I be tested for autoimmune atrophic gastritis or pernicious anemia?,Do I need vitamin B12 injections or supplements, and for how long?,Is there any chance this tumor could spread, and what signs should I watch for?,Should I or my family members be tested for inherited conditions like MEN1?,Are there any clinical trials or new treatments I should know about?

Common questions about OBSOLETE: Gastric neuroendocrine tumor type 1