Overview
Familial restrictive cardiomyopathy type 3 is a rare inherited heart condition that has been reclassified (marked as 'obsolete') in medical databases, meaning it may now be categorized under a broader or updated disease classification. Restrictive cardiomyopathy (RCM) in general is a condition where the walls of the heart's lower chambers (ventricles) become stiff and rigid, preventing them from filling properly with blood between heartbeats. Although the heart may pump normally at first, the stiffness makes it harder for the heart to relax and fill, which leads to a backup of blood and fluid in the body. Symptoms typically include shortness of breath, fatigue, swelling in the legs and abdomen, difficulty exercising, and irregular heartbeats. Over time, this can lead to heart failure. Familial forms of restrictive cardiomyopathy are caused by inherited gene mutations and tend to run in families. Treatment is mainly supportive and focuses on managing symptoms of heart failure, controlling heart rhythm problems, and in severe cases, considering heart transplantation. Because this specific subtype has been reclassified, patients previously diagnosed with this condition should work with their cardiologist and geneticist to understand how their diagnosis fits into current medical classifications.
Also known as:
Key symptoms:
Shortness of breath, especially during activity or when lying downFatigue and low energySwelling in the legs, ankles, or feetSwelling or fluid buildup in the abdomenDifficulty exercising or reduced ability to be activeIrregular or fast heartbeat (palpitations)Fainting or feeling lightheadedChest discomfortCoughing, especially at nightPoor appetite or feeling full quicklyWeight gain from fluid retention
Autosomal dominant
Passed on from just one parent; each child has about a 50% chance of inheriting it
Variable
Can begin at different ages, from infancy through adulthood
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Familial restrictive cardiomyopathy type 3.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for OBSOLETE: Familial restrictive cardiomyopathy type 3 at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Familial restrictive cardiomyopathy type 3.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Familial restrictive cardiomyopathy type 3.
Community
No community posts yet. Be the first to share your experience with OBSOLETE: Familial restrictive cardiomyopathy type 3.
Start the conversation →Latest news about OBSOLETE: Familial restrictive cardiomyopathy type 3
No recent news articles for OBSOLETE: Familial restrictive cardiomyopathy type 3.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Has my diagnosis been updated to reflect current disease classifications, and what is the most accurate name for my condition now?,What specific gene mutation was found, and what does it mean for my family members?,How often should I have echocardiograms and other heart monitoring tests?,Are there any activity restrictions I should follow, and is exercise safe for me?,At what point would heart transplantation be considered, and should I be evaluated for transplant listing?,What symptoms should prompt me to seek emergency care immediately?,Are there any clinical trials or new treatments being studied for restrictive cardiomyopathy that I might be eligible for?
Common questions about OBSOLETE: Familial restrictive cardiomyopathy type 3
What is OBSOLETE: Familial restrictive cardiomyopathy type 3?
Familial restrictive cardiomyopathy type 3 is a rare inherited heart condition that has been reclassified (marked as 'obsolete') in medical databases, meaning it may now be categorized under a broader or updated disease classification. Restrictive cardiomyopathy (RCM) in general is a condition where the walls of the heart's lower chambers (ventricles) become stiff and rigid, preventing them from filling properly with blood between heartbeats. Although the heart may pump normally at first, the stiffness makes it harder for the heart to relax and fill, which leads to a backup of blood and fluid
How is OBSOLETE: Familial restrictive cardiomyopathy type 3 inherited?
OBSOLETE: Familial restrictive cardiomyopathy type 3 follows a autosomal dominant inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.