Overview
Extensive peripapillary myelinated nerve fibers (also called extensive peripapillary myelinated retinal nerve fibers) is a rare eye condition that is now considered an outdated or 'obsolete' diagnostic category in some classification systems, meaning it was previously listed as a distinct condition but has since been reclassified or merged with related eye findings. In this condition, the nerve fibers around the optic disc — the spot at the back of the eye where the optic nerve connects — have an unusual white, feathery coating called myelin. Normally, myelin does not appear on the nerve fibers inside the eye, so when it does, it can affect how the eye looks and sometimes how well it works. People with this finding may experience reduced sharpness of vision, blind spots, or a larger-than-normal area of reduced vision near the center of their visual field. In some cases, the condition is linked to nearsightedness (myopia). Many people have no symptoms at all and the finding is discovered during a routine eye exam. Because this entry is now marked as obsolete in rare disease databases, patients should work closely with an ophthalmologist to understand how this finding applies to their specific situation and whether it overlaps with a currently recognized diagnosis.
Key symptoms:
Blurry or reduced sharpness of visionBlind spots in the visual fieldEnlarged blind spot near the center of visionNearsightedness (difficulty seeing things far away)White or bright patches visible at the back of the eye on examPossible reduced contrast sensitivity
Variable
Can begin at different ages, from infancy through adulthood
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Extensive peripapillary myelinated nerve fibers.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for OBSOLETE: Extensive peripapillary myelinated nerve fibers at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Extensive peripapillary myelinated nerve fibers.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Extensive peripapillary myelinated nerve fibers.
Community
No community posts yet. Be the first to share your experience with OBSOLETE: Extensive peripapillary myelinated nerve fibers.
Start the conversation →Latest news about OBSOLETE: Extensive peripapillary myelinated nerve fibers
No recent news articles for OBSOLETE: Extensive peripapillary myelinated nerve fibers.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Is my diagnosis still considered 'extensive peripapillary myelinated nerve fibers,' or has it been reclassified under a different name?,How much is my vision affected, and is it likely to change over time?,Do I need glasses or any other treatment to protect or improve my vision?,Should my children or other family members be screened for this finding?,How often should I have follow-up eye exams?,Are there any activities I should avoid because of this condition?,Is there any research or clinical trial I should know about?
Common questions about OBSOLETE: Extensive peripapillary myelinated nerve fibers
What is OBSOLETE: Extensive peripapillary myelinated nerve fibers?
Extensive peripapillary myelinated nerve fibers (also called extensive peripapillary myelinated retinal nerve fibers) is a rare eye condition that is now considered an outdated or 'obsolete' diagnostic category in some classification systems, meaning it was previously listed as a distinct condition but has since been reclassified or merged with related eye findings. In this condition, the nerve fibers around the optic disc — the spot at the back of the eye where the optic nerve connects — have an unusual white, feathery coating called myelin. Normally, myelin does not appear on the nerve fiber