Overview
Envenomization by Bothrops lanceolatus refers to poisoning caused by the bite of the Martinique lancehead pit viper (Bothrops lanceolatus), a venomous snake found exclusively on the Caribbean island of Martinique. This is not a genetic disease but rather a medical condition resulting from snakebite envenomation. This entry is marked as 'OBSOLETE' in the Orphanet database, meaning it is no longer actively classified as a rare disease entry, likely because it is better categorized as a toxicological emergency rather than a rare disease. When a person is bitten by this snake, the venom can cause serious problems throughout the body. The venom of Bothrops lanceolatus is unusual compared to other pit vipers because it is particularly associated with blood clotting complications, including thrombosis (formation of blood clots in blood vessels). Victims may experience local symptoms at the bite site such as severe pain, swelling, and tissue damage. More dangerously, the venom can trigger clot formation in blood vessels supplying the brain, lungs, and other organs, potentially leading to stroke, heart attack, or organ failure. Treatment involves emergency medical care, including the use of specific antivenom (Bothrofav, produced by the Institut Pasteur) when available, supportive care, and management of clotting complications. Prompt medical attention is critical to prevent life-threatening outcomes. Without treatment, envenomation can be fatal or lead to permanent disability.
Key symptoms:
Severe pain at the bite siteSwelling around the biteBruising and skin discoloration near the woundTissue death around the bite areaBlood clots forming in blood vesselsStroke symptoms such as sudden weakness or speech difficultyDifficulty breathingNausea and vomitingHeadacheBleeding from the wound that is hard to stopOrgan damage from blood clotsLow blood pressureRapid heartbeat
Variable
Can begin at different ages, from infancy through adulthood
FDA & Trial Timeline
2 eventsAnavip: FDA approved
Management of adult and pediatric patients with North American rattlesnake envenomation
CroFab: FDA approved
Treatment of minimal and moderate North American Crotalidae envenomation
Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.
Treatments
2 availableAnavip
Management of adult and pediatric patients with North American rattlesnake envenomation
CroFab
Treatment of minimal and moderate North American Crotalidae envenomation
Clinical Trials
View all trials with filters →No actively recruiting trials found for OBSOLETE: Envenomization by Bothrops lanceolatus at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Envenomization by Bothrops lanceolatus.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Envenomization by Bothrops lanceolatus.
Community
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Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Was antivenom administered, and was it given in time to be effective?,Are there any signs of blood clots in my brain or other organs?,What follow-up tests do I need to check for delayed complications?,How should I care for the bite wound at home?,What symptoms should prompt me to return to the emergency room?,Will I have any long-term effects from this envenomation?,How can I reduce my risk of future snake bites on Martinique?
Common questions about OBSOLETE: Envenomization by Bothrops lanceolatus
What is OBSOLETE: Envenomization by Bothrops lanceolatus?
Envenomization by Bothrops lanceolatus refers to poisoning caused by the bite of the Martinique lancehead pit viper (Bothrops lanceolatus), a venomous snake found exclusively on the Caribbean island of Martinique. This is not a genetic disease but rather a medical condition resulting from snakebite envenomation. This entry is marked as 'OBSOLETE' in the Orphanet database, meaning it is no longer actively classified as a rare disease entry, likely because it is better categorized as a toxicological emergency rather than a rare disease. When a person is bitten by this snake, the venom can cause
What treatment and support options exist for OBSOLETE: Envenomization by Bothrops lanceolatus?
2 patient support programs are currently tracked on UniteRare for OBSOLETE: Envenomization by Bothrops lanceolatus. See the treatments and support programs sections for copay assistance, eligibility, and contact details.