Overview
Developmental delay-deafness syndrome, Hildebrand type, is an extremely rare genetic condition that was previously described in medical literature but has since been classified as 'obsolete' in disease databases like Orphanet. This means that the condition may have been reclassified, merged with another diagnosis, or the original description may no longer be considered a distinct disease entity based on updated genetic and clinical understanding. When it was described, this syndrome was characterized by a combination of developmental delay (meaning children reached milestones like sitting, walking, and talking later than expected) and hearing loss (deafness). Children affected by this condition would have had difficulties with learning, communication, and overall development. The hearing loss could range from mild to severe and would further complicate speech and language development. Because this entry is now obsolete, patients or families who were previously given this diagnosis should speak with a clinical geneticist to determine whether a more current and specific diagnosis applies to their situation. Advances in genetic testing, particularly whole exome and whole genome sequencing, have allowed many previously grouped conditions to be reclassified into more precise diagnoses with better-defined genetic causes and management strategies. Treatment would have been supportive, focusing on hearing aids or cochlear implants for hearing loss, speech therapy, occupational therapy, and educational support for developmental delays.
Key symptoms:
Delayed developmental milestonesHearing loss or deafnessDelayed speech and language developmentLearning difficultiesDifficulty with communication
Infantile
Begins in infancy, roughly 1 month to 2 years old
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type.
Community
No community posts yet. Be the first to share your experience with OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type.
Start the conversation →Latest news about OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type
No recent news articles for OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Since this diagnosis is now considered obsolete, what is the most current diagnosis for my child's condition?,Should we pursue whole exome or whole genome sequencing to get a more precise genetic diagnosis?,What early intervention services should we start right away?,What type of hearing support would be most beneficial — hearing aids or cochlear implants?,Are there any clinical trials or research studies that might be relevant?,What is the expected developmental trajectory for my child?,Are there any other medical issues we should screen for?
Common questions about OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type
What is OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type?
Developmental delay-deafness syndrome, Hildebrand type, is an extremely rare genetic condition that was previously described in medical literature but has since been classified as 'obsolete' in disease databases like Orphanet. This means that the condition may have been reclassified, merged with another diagnosis, or the original description may no longer be considered a distinct disease entity based on updated genetic and clinical understanding. When it was described, this syndrome was characterized by a combination of developmental delay (meaning children reached milestones like sitting, wa
At what age does OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type typically begin?
Typical onset of OBSOLETE: Developmental delay-deafness syndrome, Hildebrand type is infantile. Age of onset can vary across affected individuals.