Overview
Dacryocystitis-osteopoikilosis syndrome is an extremely rare condition that has been described in medical literature but is now considered an obsolete diagnostic term, meaning it is no longer recognized as a distinct syndrome by current medical classification systems. The condition was originally described as a combination of two features: dacryocystitis, which is inflammation or infection of the tear sac (the small pouch near the inner corner of the eye that collects tears before they drain into the nose), and osteopoikilosis, a usually harmless bone condition where small, round, dense spots appear on X-rays of various bones throughout the body. Dacryocystitis can cause tearing, redness, swelling, and pain near the inner corner of the eye, and sometimes discharge or recurrent infections. Osteopoikilosis is typically discovered incidentally on X-rays taken for other reasons and usually causes no symptoms on its own. Because this syndrome designation is now obsolete, it is likely that the two features were coincidentally present together or that the condition has been reclassified under a different or broader diagnosis. Patients who were previously given this diagnosis should discuss with their doctors whether their symptoms fit into a currently recognized condition. Treatment would generally focus on managing each component separately — antibiotics or surgery for dacryocystitis, and typically no treatment needed for osteopoikilosis.
Also known as:
Key symptoms:
Tearing or watery eyesSwelling near the inner corner of the eyeRedness around the tear sac areaEye pain or tenderness near the nose bridgeDischarge from the eye or tear ductRecurrent eye infectionsSmall dense bone spots seen on X-raysOccasional mild joint pain or stiffness
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Dacryocystitis-osteopoikilosis syndrome.
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Specialists
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Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
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Caregiver Resources
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Questions for your doctor
Bring these to your next appointment
- Q1.Is this diagnosis still considered valid, or should my condition be reclassified under a current diagnosis?,Are the dacryocystitis and bone findings related, or are they separate conditions?,Do I need surgery to fix my tear duct drainage, or can it be managed with medication?,Should my family members be screened for osteopoikilosis or related conditions?,Is genetic testing recommended to look for an underlying cause?,How often should I have follow-up eye exams?,Are there any activities or environmental factors I should avoid to prevent recurrent eye infections?
Common questions about OBSOLETE: Dacryocystitis-osteopoikilosis syndrome
What is OBSOLETE: Dacryocystitis-osteopoikilosis syndrome?
Dacryocystitis-osteopoikilosis syndrome is an extremely rare condition that has been described in medical literature but is now considered an obsolete diagnostic term, meaning it is no longer recognized as a distinct syndrome by current medical classification systems. The condition was originally described as a combination of two features: dacryocystitis, which is inflammation or infection of the tear sac (the small pouch near the inner corner of the eye that collects tears before they drain into the nose), and osteopoikilosis, a usually harmless bone condition where small, round, dense spots