Overview
Congenital valvular dysplasia is a rare heart condition present from birth in which one or more of the heart's valves do not form properly. The term 'OBSOLETE' in the disease name means that this specific classification is no longer actively used in current medical databases, and the condition may now be categorized under more specific diagnoses depending on which valve is affected and the nature of the abnormality. Heart valves act like one-way doors that keep blood flowing in the right direction through the heart's four chambers. When these valves are dysplastic (meaning they are abnormally formed), they may not open or close properly, leading to problems with blood flow. This can cause the heart to work harder than normal. Symptoms can vary widely depending on which valve or valves are affected and how severe the malformation is. Some patients may have mild symptoms that are discovered incidentally, while others may show signs of heart failure early in life, including difficulty breathing, poor feeding in infants, fatigue, and failure to grow at a normal rate. A heart murmur is often the first clue that something may be wrong. Treatment depends on the severity of the valve problem. Mild cases may only need regular monitoring by a cardiologist. More severe cases may require medications to help the heart work more efficiently, or surgical repair or replacement of the affected valve. Advances in cardiac surgery and catheter-based procedures have significantly improved outcomes for many patients with congenital valve abnormalities.
Key symptoms:
Heart murmur detected by a doctorShortness of breath or difficulty breathingPoor feeding in infantsFailure to gain weight or grow normallyFatigue or low energySwelling in the legs, ankles, or abdomenBluish color of the skin or lips (cyanosis)Rapid or irregular heartbeatFainting or dizzinessChest pain or discomfortFrequent respiratory infectionsExercise intolerance
Variable
Can be inherited in different ways depending on the underlying gene
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Congenital valvular dysplasia.
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Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Congenital valvular dysplasia.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Congenital valvular dysplasia.
Community
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Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Which heart valve or valves are affected, and how severe is the problem?,Will my child need surgery, and if so, when is the best time?,Are there any activity or exercise restrictions we should follow?,Could this condition be part of a genetic syndrome, and should we pursue genetic testing?,How often will follow-up echocardiograms and cardiology visits be needed?,What warning signs should prompt us to seek emergency care?,Is antibiotic prophylaxis needed before dental or surgical procedures?
Common questions about OBSOLETE: Congenital valvular dysplasia
What is OBSOLETE: Congenital valvular dysplasia?
Congenital valvular dysplasia is a rare heart condition present from birth in which one or more of the heart's valves do not form properly. The term 'OBSOLETE' in the disease name means that this specific classification is no longer actively used in current medical databases, and the condition may now be categorized under more specific diagnoses depending on which valve is affected and the nature of the abnormality. Heart valves act like one-way doors that keep blood flowing in the right direction through the heart's four chambers. When these valves are dysplastic (meaning they are abnormally
At what age does OBSOLETE: Congenital valvular dysplasia typically begin?
Typical onset of OBSOLETE: Congenital valvular dysplasia is neonatal. Age of onset can vary across affected individuals.