Overview
Central polydactyly of toes, unilateral, is a rare congenital condition where a person is born with one or more extra toes in the central part of one foot. The term "central" means the extra toe or toes appear among the middle toes (typically the second, third, or fourth toe area), rather than on the outer edge of the foot. "Unilateral" means it affects only one foot. This condition is present at birth and is usually noticed right away. It is important to note that this specific Orphanet entry (295183) is labeled as "OBSOLETE," meaning it has been retired or merged into a broader classification of polydactyly conditions. Patients with this finding may now be classified under more general categories of central polydactyly or preaxial/postaxial polydactyly of the foot. The extra toe may be fully formed with bones, joints, and a nail, or it may be a smaller, less developed digit. In many cases, the extra toe does not cause pain but can make it difficult to find comfortable shoes and may affect walking. Treatment typically involves surgical removal of the extra toe, usually performed in early childhood. The surgery aims to create a foot that functions well and looks as typical as possible. Outcomes after surgery are generally very good, and most children go on to walk and run normally.
Key symptoms:
Extra toe on one foot in the middle toe areaWider-than-normal forefoot on the affected sideDifficulty fitting into standard shoesPossible webbing between the extra toe and neighboring toesThe extra toe may be fully formed or underdevelopedPossible discomfort or rubbing when wearing shoesAltered walking pattern in some casesCosmetic concern about foot appearance
Variable
Can be inherited in different ways depending on the underlying gene
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Central polydactyly of toes, unilateral.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for OBSOLETE: Central polydactyly of toes, unilateral at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Central polydactyly of toes, unilateral.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Central polydactyly of toes, unilateral.
Community
No community posts yet. Be the first to share your experience with OBSOLETE: Central polydactyly of toes, unilateral.
Start the conversation →Latest news about OBSOLETE: Central polydactyly of toes, unilateral
No recent news articles for OBSOLETE: Central polydactyly of toes, unilateral.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Is my child's extra toe an isolated finding, or could it be part of a genetic syndrome?,What is the best age for surgical correction in my child's case?,What does the bone structure of the extra toe look like on X-ray, and how does that affect the surgical plan?,What are the risks and expected outcomes of the surgery?,Will my child need any follow-up surgeries as they grow?,Should we see a geneticist or have genetic testing done?,What is the chance that future children could also have polydactyly?
Common questions about OBSOLETE: Central polydactyly of toes, unilateral
What is OBSOLETE: Central polydactyly of toes, unilateral?
Central polydactyly of toes, unilateral, is a rare congenital condition where a person is born with one or more extra toes in the central part of one foot. The term "central" means the extra toe or toes appear among the middle toes (typically the second, third, or fourth toe area), rather than on the outer edge of the foot. "Unilateral" means it affects only one foot. This condition is present at birth and is usually noticed right away. It is important to note that this specific Orphanet entry (295183) is labeled as "OBSOLETE," meaning it has been retired or merged into a broader classificati
At what age does OBSOLETE: Central polydactyly of toes, unilateral typically begin?
Typical onset of OBSOLETE: Central polydactyly of toes, unilateral is neonatal. Age of onset can vary across affected individuals.