OBSOLETE: Central polydactyly of toes, unilateral

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ORPHA:295183
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8Treatment centers

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Overview

Central polydactyly of toes, unilateral, is a rare congenital condition where a person is born with one or more extra toes in the central part of one foot. The term "central" means the extra toe or toes appear among the middle toes (typically the second, third, or fourth toe area), rather than on the outer edge of the foot. "Unilateral" means it affects only one foot. This condition is present at birth and is usually noticed right away. It is important to note that this specific Orphanet entry (295183) is labeled as "OBSOLETE," meaning it has been retired or merged into a broader classification of polydactyly conditions. Patients with this finding may now be classified under more general categories of central polydactyly or preaxial/postaxial polydactyly of the foot. The extra toe may be fully formed with bones, joints, and a nail, or it may be a smaller, less developed digit. In many cases, the extra toe does not cause pain but can make it difficult to find comfortable shoes and may affect walking. Treatment typically involves surgical removal of the extra toe, usually performed in early childhood. The surgery aims to create a foot that functions well and looks as typical as possible. Outcomes after surgery are generally very good, and most children go on to walk and run normally.

Also known as:

Key symptoms:

Extra toe on one foot in the middle toe areaWider-than-normal forefoot on the affected sideDifficulty fitting into standard shoesPossible webbing between the extra toe and neighboring toesThe extra toe may be fully formed or underdevelopedPossible discomfort or rubbing when wearing shoesAltered walking pattern in some casesCosmetic concern about foot appearance

Inheritance

Variable

Can be inherited in different ways depending on the underlying gene

Age of Onset

Neonatal

Begins at or shortly after birth (first 4 weeks)

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for OBSOLETE: Central polydactyly of toes, unilateral.

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No actively recruiting trials found for OBSOLETE: Central polydactyly of toes, unilateral at this time.

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No specialists are currently listed for OBSOLETE: Central polydactyly of toes, unilateral.

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Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to OBSOLETE: Central polydactyly of toes, unilateral.

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Community

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Caregiver Resources

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Questions for your doctor

Bring these to your next appointment

  • Q1.Is my child's extra toe an isolated finding, or could it be part of a genetic syndrome?,What is the best age for surgical correction in my child's case?,What does the bone structure of the extra toe look like on X-ray, and how does that affect the surgical plan?,What are the risks and expected outcomes of the surgery?,Will my child need any follow-up surgeries as they grow?,Should we see a geneticist or have genetic testing done?,What is the chance that future children could also have polydactyly?

Common questions about OBSOLETE: Central polydactyly of toes, unilateral

What is OBSOLETE: Central polydactyly of toes, unilateral?

Central polydactyly of toes, unilateral, is a rare congenital condition where a person is born with one or more extra toes in the central part of one foot. The term "central" means the extra toe or toes appear among the middle toes (typically the second, third, or fourth toe area), rather than on the outer edge of the foot. "Unilateral" means it affects only one foot. This condition is present at birth and is usually noticed right away. It is important to note that this specific Orphanet entry (295183) is labeled as "OBSOLETE," meaning it has been retired or merged into a broader classificati

At what age does OBSOLETE: Central polydactyly of toes, unilateral typically begin?

Typical onset of OBSOLETE: Central polydactyly of toes, unilateral is neonatal. Age of onset can vary across affected individuals.