Overview
Autosomal recessive limb-girdle muscular dystrophy with cerebellar involvement is an extremely rare inherited muscle disease that affects both the muscles around the shoulders and hips (called the limb-girdle muscles) and the cerebellum, which is the part of the brain that controls balance and coordination. This condition is now considered an obsolete classification in medical databases, meaning it may have been reclassified or merged with another recognized disease entity as scientific understanding has advanced. Patients with this condition typically experience progressive weakness in the muscles closest to the body's trunk — the upper arms, thighs, hips, and shoulders — making it increasingly difficult to walk, climb stairs, or lift objects. In addition to muscle weakness, affected individuals also develop cerebellar problems, which can cause unsteady walking (ataxia), difficulty with coordination, slurred speech, and problems with fine motor tasks. Because this is an obsolete classification, patients who were previously diagnosed under this label may now fall under a more specific limb-girdle muscular dystrophy subtype. Treatment is primarily supportive and may include physical therapy, occupational therapy, assistive devices for mobility, and management of cerebellar symptoms. There is currently no cure for this group of conditions, though research into gene therapies and other disease-modifying treatments is ongoing.
Key symptoms:
Weakness in the shoulders and upper armsWeakness in the hips and thighsDifficulty walking or climbing stairsUnsteady or wobbly walking (ataxia)Poor coordination and balanceSlurred or slow speechDifficulty with fine motor tasks like writing or buttoning clothesProgressive loss of muscle bulk (muscle wasting)Fatigue during physical activityDifficulty rising from a seated or lying positionTremor or shaking movementsEye movement abnormalities
Autosomal recessive
Passed on when both parents carry the same gene change; often skips generations
Variable
Can begin at different ages, from infancy through adulthood
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Autosomal recessive limb-girdle muscular dystrophy with cerebellar involvement.
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Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Autosomal recessive limb-girdle muscular dystrophy with cerebellar involvement.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Autosomal recessive limb-girdle muscular dystrophy with cerebellar involvement.
Community
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Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Has my condition been reclassified under a more specific limb-girdle muscular dystrophy subtype?,What genetic testing should I have to identify the exact cause of my condition?,How quickly is the disease likely to progress in my case?,Should I be monitored for heart or breathing problems?,What physical therapy or rehabilitation programs would be most helpful?,Are there any clinical trials or emerging therapies I might be eligible for?,What resources or support groups are available for people with limb-girdle muscular dystrophy?
Common questions about OBSOLETE: Autosomal recessive limb-girdle muscular dystrophy with cerebellar involvement
What is OBSOLETE: Autosomal recessive limb-girdle muscular dystrophy with cerebellar involvement?
Autosomal recessive limb-girdle muscular dystrophy with cerebellar involvement is an extremely rare inherited muscle disease that affects both the muscles around the shoulders and hips (called the limb-girdle muscles) and the cerebellum, which is the part of the brain that controls balance and coordination. This condition is now considered an obsolete classification in medical databases, meaning it may have been reclassified or merged with another recognized disease entity as scientific understanding has advanced. Patients with this condition typically experience progressive weakness in the m
How is OBSOLETE: Autosomal recessive limb-girdle muscular dystrophy with cerebellar involvement inherited?
OBSOLETE: Autosomal recessive limb-girdle muscular dystrophy with cerebellar involvement follows a autosomal recessive inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.