Overview
Adactyly of foot, unilateral, refers to a rare congenital limb condition in which a person is born missing all toes on one foot. The term 'adactyly' literally means 'absence of digits.' In this case, only one foot is affected (unilateral), while the other foot typically has normal toes. This condition is present at birth and is usually noticed immediately after delivery. It is important to note that this specific Orphanet entry is labeled as 'OBSOLETE,' meaning it may have been reclassified, merged with another condition, or is no longer used as a standalone diagnosis in current medical classification systems. Patients with this condition may now be classified under broader categories of limb reduction defects or terminal transverse limb deficiencies. The absence of toes on one foot can affect balance, walking, and the ability to push off during movement. However, many individuals adapt well, especially with early intervention. Treatment is generally supportive and may include custom footwear, orthotics, physical therapy, and in some cases prosthetic devices to improve function and comfort. Surgical options may occasionally be considered depending on the anatomy of the foot. The condition does not typically affect overall life expectancy, and most people lead active, fulfilling lives with appropriate support.
Also known as:
Key symptoms:
Complete absence of all toes on one footShortened appearance of the affected footDifficulty with balance when walkingAltered gait or walking patternDifficulty fitting into standard shoesReduced ability to push off the ground when walking or running
Variable
Can be inherited in different ways depending on the underlying gene
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for OBSOLETE: Adactyly of foot, unilateral.
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Specialists
View all specialists →No specialists are currently listed for OBSOLETE: Adactyly of foot, unilateral.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to OBSOLETE: Adactyly of foot, unilateral.
Community
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Caregiver Resources
NORD Caregiver Resources
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Mental Health Support
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Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.Is this condition isolated, or could it be part of a broader genetic syndrome?,Should we pursue genetic testing to look for an underlying cause?,What type of orthotic or prosthetic support would be most helpful for my child?,How often should we follow up with an orthopedic specialist as my child grows?,Are there physical therapy programs you recommend for children with limb differences?,Will this condition affect my child's ability to walk, run, and participate in sports?,Are there support groups or resources for families of children with limb differences?
Common questions about OBSOLETE: Adactyly of foot, unilateral
What is OBSOLETE: Adactyly of foot, unilateral?
Adactyly of foot, unilateral, refers to a rare congenital limb condition in which a person is born missing all toes on one foot. The term 'adactyly' literally means 'absence of digits.' In this case, only one foot is affected (unilateral), while the other foot typically has normal toes. This condition is present at birth and is usually noticed immediately after delivery. It is important to note that this specific Orphanet entry is labeled as 'OBSOLETE,' meaning it may have been reclassified, merged with another condition, or is no longer used as a standalone diagnosis in current medical classi
At what age does OBSOLETE: Adactyly of foot, unilateral typically begin?
Typical onset of OBSOLETE: Adactyly of foot, unilateral is neonatal. Age of onset can vary across affected individuals.