Overview
Non-recovering obstetric brachial plexus lesion (also called non-recovering birth brachial plexus palsy or persistent neonatal brachial plexus injury) is a condition that occurs when the nerves that control movement and feeling in the shoulder, arm, and hand are damaged during birth and do not heal on their own. The brachial plexus is a network of nerves running from the neck down into the arm. During a difficult delivery, these nerves can be stretched, compressed, or torn. While many babies with birth-related brachial plexus injuries recover within the first few months of life, some do not. When the nerve damage is severe enough that function does not return naturally, the condition is classified as non-recovering. Affected children may have a limp or paralyzed arm, limited ability to move the shoulder, elbow, wrist, or hand, and differences in arm size and strength compared to the unaffected side. The severity depends on which nerves are damaged and how badly. Some children have weakness mainly in the upper arm and shoulder (known as Erb's palsy pattern), while others have more widespread involvement including the hand (Klumpke's palsy pattern). In the most severe cases, the entire arm may be affected. Treatment typically involves a combination of physical therapy, occupational therapy, and in many cases surgery. Nerve surgery (such as nerve grafting or nerve transfers) is often considered when recovery stalls, usually between 3 and 9 months of age. Later surgeries on muscles, tendons, or bones may be needed as the child grows to improve function and correct joint problems. While treatment can significantly improve outcomes, complete recovery of normal arm function is uncommon in non-recovering cases.
Also known as:
Key symptoms:
Limp or floppy arm on one side at birthInability to move the shoulderInability to bend the elbowWeak or absent grip in the affected handArm held in an unusual position against the bodyDifference in arm size between the two sidesLimited ability to rotate the forearmStiffness or contractures in the shoulder or elbow jointsDecreased or absent feeling in the affected armMuscle wasting in the affected armShoulder joint instability or dislocationDifficulty with daily tasks requiring two handsAbnormal posture of the wrist or fingers
Sporadic
Usually appears on its own, not inherited from a parent
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for Non-recovering obstetric brachial plexus lesion.
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Specialists
View all specialists →No specialists are currently listed for Non-recovering obstetric brachial plexus lesion.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Non-recovering obstetric brachial plexus lesion.
Community
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Caregiver Resources
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Questions for your doctor
Bring these to your next appointment
- Q1.How severe is my child's nerve injury, and which specific nerves are affected?,Is my child a candidate for nerve surgery, and what is the ideal timing?,What improvements can we realistically expect with and without surgery?,How often should my child have physical and occupational therapy?,What exercises should we be doing at home to help recovery?,Will my child need additional surgeries as they grow?,Are there any clinical trials or new treatments we should know about?
Common questions about Non-recovering obstetric brachial plexus lesion
What is Non-recovering obstetric brachial plexus lesion?
Non-recovering obstetric brachial plexus lesion (also called non-recovering birth brachial plexus palsy or persistent neonatal brachial plexus injury) is a condition that occurs when the nerves that control movement and feeling in the shoulder, arm, and hand are damaged during birth and do not heal on their own. The brachial plexus is a network of nerves running from the neck down into the arm. During a difficult delivery, these nerves can be stretched, compressed, or torn. While many babies with birth-related brachial plexus injuries recover within the first few months of life, some do not. W
How is Non-recovering obstetric brachial plexus lesion inherited?
Non-recovering obstetric brachial plexus lesion follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does Non-recovering obstetric brachial plexus lesion typically begin?
Typical onset of Non-recovering obstetric brachial plexus lesion is neonatal. Age of onset can vary across affected individuals.