Overview
Mucinous tubular and spindle cell renal carcinoma (MTSCC) is a rare type of kidney cancer. It is also sometimes called mucinous tubular and spindle cell carcinoma of the kidney. This tumor arises from the cells lining the tiny tubes inside the kidney. Under the microscope, it has a distinctive appearance with tube-like (tubular) structures and elongated (spindle-shaped) cells surrounded by a mucin-rich (jelly-like) substance. MTSCC is generally considered a low-grade cancer, meaning it tends to grow slowly and has a favorable outlook compared to many other types of kidney cancer. Many people with MTSCC have no symptoms at all, and the tumor is often discovered by accident during imaging tests done for other reasons. When symptoms do occur, they may include blood in the urine, pain in the side or lower back, or a mass that can be felt in the abdomen. Some patients may experience fatigue, unexplained weight loss, or general feelings of being unwell. The main treatment for MTSCC is surgery to remove the tumor, which may involve removing part of the kidney (partial nephrectomy) or the entire kidney (radical nephrectomy). Because this cancer is usually low-grade and tends not to spread, surgery alone is often curative. In the rare cases where the tumor has more aggressive features or has spread beyond the kidney, additional treatments such as targeted therapy or immunotherapy may be considered, though there is limited data on the best approach for advanced disease. Regular follow-up with imaging and blood tests is important after treatment to watch for any recurrence.
Key symptoms:
Blood in the urine (may be visible or only found on lab tests)Pain in the side or flank areaA lump or mass felt in the abdomenLower back painUnexplained weight lossFatigue or tirednessLoss of appetiteFever without an obvious causeGeneral feeling of being unwellNo symptoms at all (found incidentally on imaging)
Sporadic
Usually appears on its own, not inherited from a parent
Adult
Begins in adulthood (age 18 or older)
Treatments
No FDA-approved treatments are currently listed for Mucinous tubular and spindle cell renal carcinoma.
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Specialists
View all specialists →No specialists are currently listed for Mucinous tubular and spindle cell renal carcinoma.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Mucinous tubular and spindle cell renal carcinoma.
Community
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Caregiver Resources
NORD Caregiver Resources
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Mental Health Support
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Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.What stage is my kidney cancer, and has it spread beyond the kidney?,Is a partial nephrectomy (kidney-sparing surgery) an option for me, or do I need the whole kidney removed?,What does the pathology report show about the grade and aggressiveness of my tumor?,How often will I need follow-up imaging and blood tests after surgery?,Are there any lifestyle changes I should make to protect my remaining kidney function?,Should I be concerned about this type of cancer running in my family?,If the cancer were to come back or spread, what treatment options would be available?
Common questions about Mucinous tubular and spindle cell renal carcinoma
What is Mucinous tubular and spindle cell renal carcinoma?
Mucinous tubular and spindle cell renal carcinoma (MTSCC) is a rare type of kidney cancer. It is also sometimes called mucinous tubular and spindle cell carcinoma of the kidney. This tumor arises from the cells lining the tiny tubes inside the kidney. Under the microscope, it has a distinctive appearance with tube-like (tubular) structures and elongated (spindle-shaped) cells surrounded by a mucin-rich (jelly-like) substance. MTSCC is generally considered a low-grade cancer, meaning it tends to grow slowly and has a favorable outlook compared to many other types of kidney cancer. Many people
How is Mucinous tubular and spindle cell renal carcinoma inherited?
Mucinous tubular and spindle cell renal carcinoma follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does Mucinous tubular and spindle cell renal carcinoma typically begin?
Typical onset of Mucinous tubular and spindle cell renal carcinoma is adult. Age of onset can vary across affected individuals.