Midline interhemispheric variant of holoprosencephaly

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ORPHA:93926OMIM:157170Q04.2
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1Specialists8Treatment centers

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

Clinical phenotype terms— hover any for plain English:

Orphanet ↗OMIM ↗NORD ↗

FDA & Trial Timeline

10 events
Feb 2026Preemptive Analgesia for Pain and Anxiety Control in Children With MIH

October University for Modern Sciences and Arts — NA

TrialRECRUITING
Feb 2026Effects of Silver Diamine Fluoride and Intraoral Cryotherapy on Local Anesthesia in MIH-Affected Molars

Çanakkale Onsekiz Mart University — NA

TrialNOT YET RECRUITING
Jan 2026The Effect of Salvadora Persica (Miswak) Compared to Fluoridated Toothpaste on Children's Teeth Diagnosed With Molar-Incisor Hypomineralization (MIH): A Randomized Clinical Trial

King Abdulaziz University — NA

TrialNOT YET RECRUITING
Jan 2026Graphene-Reinforced CAD/CAM Restorations for MIH-Affected Molars in Adolescents: A Prospective Clinical Study

Universitat Internacional de Catalunya — NA

TrialNOT YET RECRUITING
Jan 2026Impact of Glass-Hybrid Restoration on Occlusal Force Distribution and Masticatory Muscle Activity in Children With Molar-Incisor Hypomineralization

Marmara University — NA

TrialRECRUITING
Dec 2025Clinical Evaluation of Resin Infiltration Treatment of MIH-affected Teeth in Pediatric Patients

Inonu University — NA

TrialACTIVE NOT RECRUITING
Nov 2025Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children

Ankara Yildirim Beyazıt University — NA

TrialRECRUITING
Nov 2025Hydroxyapatite vs Fluoride Toothpaste for MIH Remineralization

Dubai Health — PHASE2

TrialNOT YET RECRUITING
Oct 2025Color Change and Desensitization of Molar Incisor Hypomineralization-Affected Enamel Using Biomimetic Nano-Hydroxyapatite Toothpaste

King Abdulaziz University — NA

TrialRECRUITING
Aug 2025Etch-bleach-seal Technique in Managing Opacities Related MIH Using Icon®

Tishreen University — NA

TrialRECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for Midline interhemispheric variant of holoprosencephaly.

View clinical trials →

No actively recruiting trials found for Midline interhemispheric variant of holoprosencephaly at this time.

New trials open frequently. Follow this disease to get notified.

Search ClinicalTrials.gov ↗Join the Midline interhemispheric variant of holoprosencephaly community →

Specialists

1 foundView all specialists →
AP
Andrea Scribante, DDS, PhD
Specialist
PI on 4 active trials

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Midline interhemispheric variant of holoprosencephaly.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Midline interhemispheric variant of holoprosencephaly

Disease timeline:

New recruiting trial: Use of a Glass Ionomer Sealant in Molar Incisor Hypomineralization

A new clinical trial is recruiting patients for Midline interhemispheric variant of holoprosencephaly

New recruiting trial: Impact of Glass-Hybrid Restoration on Occlusal Force Distribution and Masticatory Muscle Activity in Children With Molar-Incisor Hypomineralization

A new clinical trial is recruiting patients for Midline interhemispheric variant of holoprosencephaly

New recruiting trial: Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children

A new clinical trial is recruiting patients for Midline interhemispheric variant of holoprosencephaly

New recruiting trial: Color Change and Desensitization of Molar Incisor Hypomineralization-Affected Enamel Using Biomimetic Nano-Hydroxyapatite Toothpaste

A new clinical trial is recruiting patients for Midline interhemispheric variant of holoprosencephaly

New recruiting trial: Preemptive Analgesia for Pain and Anxiety Control in Children With MIH

A new clinical trial is recruiting patients for Midline interhemispheric variant of holoprosencephaly

New recruiting trial: Etch-bleach-seal Technique in Managing Opacities Related MIH Using Icon®

A new clinical trial is recruiting patients for Midline interhemispheric variant of holoprosencephaly

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Midline interhemispheric variant of holoprosencephaly

Which specialists treat Midline interhemispheric variant of holoprosencephaly?

1 specialists and care centers treating Midline interhemispheric variant of holoprosencephaly are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.