Hypertrichosis cubiti

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ORPHA:2220OMIM:139600Q84.2
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Overview

Hypertrichosis cubiti, also known as hairy elbows syndrome, is a rare congenital condition characterized by excessive hair growth (hypertrichosis) localized to the extensor surfaces of the elbows and sometimes the surrounding forearm and upper arm regions. The condition is typically present from birth or becomes noticeable during early childhood, with the hypertrichosis often becoming most prominent during childhood and potentially diminishing somewhat after puberty. The excess hair is usually fine, long, and lanugo-like or vellus in nature. Hypertrichosis cubiti primarily affects the skin and hair follicles in the elbow region. In some reported cases, the condition has been associated with short stature, and occasional reports have linked it with other features, though isolated hypertrichosis cubiti without additional anomalies is well documented. The condition is generally considered benign and does not affect internal organs or overall health in its isolated form. There is no specific medical treatment required for hypertrichosis cubiti, as it is a cosmetic condition rather than a medically threatening one. If desired for cosmetic reasons, hair removal methods such as shaving, waxing, laser hair removal, or electrolysis may be considered. Genetic counseling may be offered to affected families to discuss the inheritance pattern and recurrence risk. The condition is extremely rare, with only a limited number of families and sporadic cases reported in the medical literature.

Also known as:

Clinical phenotype terms— hover any for plain English:

Abnormality of the elbowHP:0009811Abnormal skin morphologyHP:0011121EcholaliaHP:0010529
Inheritance

Autosomal dominant

Passed on from just one parent; each child has about a 50% chance of inheriting it

Age of Onset

Childhood

Begins in childhood, roughly ages 1 to 12

Orphanet ↗OMIM ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for Hypertrichosis cubiti.

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No actively recruiting trials found for Hypertrichosis cubiti at this time.

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No specialists are currently listed for Hypertrichosis cubiti.

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Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Hypertrichosis cubiti.

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Community

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Common questions about Hypertrichosis cubiti

What is Hypertrichosis cubiti?

Hypertrichosis cubiti, also known as hairy elbows syndrome, is a rare congenital condition characterized by excessive hair growth (hypertrichosis) localized to the extensor surfaces of the elbows and sometimes the surrounding forearm and upper arm regions. The condition is typically present from birth or becomes noticeable during early childhood, with the hypertrichosis often becoming most prominent during childhood and potentially diminishing somewhat after puberty. The excess hair is usually fine, long, and lanugo-like or vellus in nature. Hypertrichosis cubiti primarily affects the skin an

How is Hypertrichosis cubiti inherited?

Hypertrichosis cubiti follows a autosomal dominant inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.

At what age does Hypertrichosis cubiti typically begin?

Typical onset of Hypertrichosis cubiti is childhood. Age of onset can vary across affected individuals.