Clinical trials for Huntington disease
45 recruiting or active trials synced from ClinicalTrials.gov.
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Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing data- RECRUITINGN/ANCT07513844Optimizing Parameters of Low-Intensity Focused Ultrasound for Pallidal Modulation in Huntington's DiseaseFirst Affiliated Hospital of Fujian Medical University
- ENROLLING BY INVITATIONPHASE2, PHASE3NCT07537075An Extension of SKY-0515 in Participants With Huntington's DiseaseSkyhawk Therapeutics, Inc.
- RECRUITINGPhase 3NCT07326709A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's DiseaseNovartis Pharmaceuticals
- RECRUITINGPHASE1, PHASE2NCT07451613Safety and Tolerability Study of Human Neural Stem Cells for Huntington's DiseaseLeslie Thompson
- RECRUITINGEarly Phase 1NCT06634628iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009CHDI Foundation, Inc.
- RECRUITINGPHASE2, PHASE3NCT07378644Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's DiseaseSkyhawk Therapeutics, Inc.
- RECRUITINGNCT07253038Evaluation of Three Tests to Assess Social Cognition in Huntington DiseaseRegion Skane · PI: Asa Petersen, MD PhD
- RECRUITINGN/ANCT07213648Modification of Threat Interpretation Bias to Reduce Anxiety in Neurodegenerative Movement Disorders (Aim 3)University of Virginia
- RECRUITINGN/ANCT06843252Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's DiseaseThe University of Texas Health Science Center at San Antonio · PI: Thiago Macedo e Cordeiro, MD, MSc
- RECRUITINGNCT06774443Hinting Task for Huntington's DiseaseUniversity Medical Center Groningen · PI: Maraike Coenen
- RECRUITINGN/ANCT07010705Digital Measures for Clinical Trial Endpoints in Huntington's DiseaseUniversity of Rochester · PI: Sugitha Maheswaran, BS
- RECRUITINGNCT06546488Cognitive Assessment Tools for Huntington's Disease.Ohio State University
- RECRUITINGNCT06448546Gut Microbiomes in HDUniversity of Central Florida · PI: Amber Southwell, PhD
- ACTIVE NOT RECRUITINGPHASE2, PHASE3NCT06873334Study of SKY-0515 for Safety, Efficacy, and Pharmacodynamics in Participants With Huntington's DiseaseSkyhawk Therapeutics, Inc. · PI: Masoud Mokhtarani, MD
- RECRUITINGPhase 2NCT06853743The NAD-HD Study: A Study to Investigate Efficacy and Safety of Nicotinamide Riboside Compared With Placebo in Huntington's DiseaseOslo University Hospital · PI: Lasse Pihlstrøm, PhD
- RECRUITINGPHASE1, PHASE2NCT06826612A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's DiseaseHoffmann-La Roche · PI: Clinical Trials
- RECRUITINGN/ANCT06626308Early Biomarkers in Premanifest Huntington's Disease Gene Carriers: a Pilot StudyUniversity Hospital, Grenoble
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT07339514A Phase I Clinical Study of ER2001 Injection for the Treatment of Early Manifest Huntington's Disease.ExoRNA Bioscience · PI: jinsheng zeng, Ph.D
- RECRUITINGN/ANCT06626412Longitudinal SV2A and MRI in Premanifest HDUniversitaire Ziekenhuizen KU Leuven
- RECRUITINGN/ANCT05360082Comparison Between [11C]UCB-J and [18F]SynVest-1 PET in HD.Universitaire Ziekenhuizen KU Leuven · PI: Koen Van Laere, MD, PhD, DSc
- RECRUITINGN/ANCT06414967Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)Poitiers University Hospital
- RECRUITINGN/ANCT06444217Gene Therapy Development and Validation for Huntington's Disease Fibro TG-HDUniversity Hospital, Angers · PI: VERNY Christophe, MD, PhD
- RECRUITINGNCT06667414Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion CarriersHoffmann-La Roche · PI: Clinical Trials
- ACTIVE NOT RECRUITINGEarly Phase 1NCT07344519The Safety and Tolerability Study With ER2001 Intravenous Injection Repetitive Treatment in Adults With Early Manifest Huntington's Disease.ExoRNA Bioscience · PI: pingyi xu, Ph.D
- RECRUITINGNCT06475898Longitudinal Endpoint Assessment of Disease Burden in HDHuntington Study Group · PI: Jamison Seabury
- RECRUITINGNCT06941662Huntington's Disease Biobank: Advancing Remote Monitoring and Deep PhenotypingStanford University · PI: Kyan Younes, MD
- RECRUITINGPhase 2NCT05509153A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion CarriersWestern Sydney Local Health District · PI: Clement Loy
- ENROLLING BY INVITATIONPhase 3NCT06312189Long-term Study to Evaluate Safety and Tolerability of Valbenazine in Participants With Chorea Associated With Huntington Disease in CanadaNeurocrine Biosciences · PI: Clinical Development Lead
- RECRUITINGN/ANCT07136844Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic PathologyCentre Hospitalier Universitaire de Liege · PI: Laurent Servais, MD
- RECRUITINGN/ANCT05808153Innovative Imaging and Cognitive BIOmarkers to Predict Huntington's Disease ProgressionAssistance Publique - Hôpitaux de Paris
- RECRUITINGNCT06082713Extracellular Vesicles for HDUniversity of Central Florida · PI: Amber Southwell, PhD
- RECRUITINGN/ANCT05596760Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their CaregiversUniversity of Washington · PI: Erin Kross, MD
- ACTIVE NOT RECRUITINGPhase 2NCT06254482An Extension Study to Evaluate the Long-Term Safety and Efficacy of Votoplam in Participants With Huntington's Disease (HD)Novartis Pharmaceuticals
- RECRUITINGN/ANCT05326451Home-based Transcranial Direct Current Stimulation Open Trial for Behavioral and Cognitive Symptoms in Huntington's DiseaseThe University of Texas Health Science Center, Houston · PI: Erin Stimming, MD
- RECRUITINGPhase 2NCT04478734Trial of the Combined Use of Thiamine and Biotin in Patients With Huntington's DiseaseFundación Pública Andaluza para la gestión de la Investigación en Sevilla · PI: Pablo Mir Rivera, MD/PhD
- RECRUITINGPHASE1, PHASE2NCT05822908A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HDVico Therapeutics B. V. · PI: Chief Medical Officer
- ACTIVE NOT RECRUITINGPhase 2NCT05686551GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's DiseaseHoffmann-La Roche · PI: Clinical Trials
- RECRUITINGNCT06203106NYSCF Scientific Discovery BiobankNew York Stem Cell Foundation Research Institute · PI: Laura Andres-Martin, PhD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT05541627A Study to Evaluate AB-1001 Striatal Administration in Adults With Early Manifest Huntington's DiseaseBrainvectis, a subsidiary of Asklepios BioPharmaceutical, Inc. (AskBio)
- ACTIVE NOT RECRUITINGPHASE2, PHASE3NCT04713982Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington DiseaseVanderbilt University Medical Center · PI: Amy E Brown, MD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT05243017Safety and Efficacy of AMT-130 in European Adults With Early Manifest Huntington's DiseaseUniQure Biopharma B.V. · PI: David Margolin, MD, PhD
- RECRUITINGNCT03434548IMarkHD: in Vivo Longitudinal Imaging of HD PathologyKing's College London · PI: Steve Williams, PhD
- ACTIVE NOT RECRUITINGPhase 3NCT04400331Open-Label Rollover Study for Continuing Valbenazine Administration for the Treatment of Chorea Associated With Huntington DiseaseNeurocrine Biosciences · PI: Chief Medical Officer
- RECRUITINGN/ANCT04012411Study of BDNF Pathway Biomarkers in the Cerebrospinal Fluid in Patients With Huntington's DiseaseUniversity Hospital, Montpellier
- ACTIVE NOT RECRUITINGNCT00051324Neurobiological Predictors of Huntington's Disease (PREDICT-HD)Jordan Schultz · PI: Jane S. Paulsen, Ph.D.