GRFoma

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ORPHA:97261E16.8C25.9
Who is this for?
Show terms as
1Active trials2Specialists8Treatment centers

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

Clinical phenotype terms— hover any for plain English:

Elevated circulating growth hormone concentrationHP:0000845Abnormal abdomen morphologyHP:0001438Zollinger-Ellison syndromeHP:0002044Neoplasm of the pancreasHP:0002894Increased circulating cortisol levelHP:0003118Palmoplantar hyperhidrosisHP:0007410Hypoactive bowel soundsHP:0030144Neoplasm of the lungHP:0100526
Orphanet ↗NORD ↗

FDA & Trial Timeline

10 events
Jul 2026A Study Investigating the Pharmacokinetics, Pharmacodynamics, Efficacy and Safety of Teverelix DP, a Gonadotropin-releasing Hormone (GnRH) Antagonist, in Patients With Advanced Prostate Cancer

Antev Ltd. — PHASE2

TrialNOT YET RECRUITING
Jun 2026Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

University of Chicago — NA

TrialRECRUITING
Oct 2025A Short-term Preoperative, Evaluating Activity and Safety of Elacestrant Monotherapy as Compared to Elacestrant + Ovarian Function Suppression (LHRH Agonist) in Premenopausal Patients With Stage I-II ER+/HER2- Breast Cancer

Gustave Roussy, Cancer Campus, Grand Paris — PHASE2

TrialRECRUITING
Aug 2024Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients

National Taiwan University Hospital — PHASE2

TrialRECRUITING
May 2024A Dose Finding Study of Debio 4228 in Participants With Advanced Prostate Cancer

Debiopharm International SA — PHASE2

TrialACTIVE NOT RECRUITING
Jul 2022GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients

Xiaojun Chen — PHASE2, PHASE3

TrialRECRUITING
Jul 2022GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients

Xiaojun Chen — PHASE2, PHASE3

TrialRECRUITING
Mar 2022Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer

Fudan University — PHASE2

TrialRECRUITING
Feb 2022Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Aadi Bioscience, Inc. — PHASE2

TrialACTIVE NOT RECRUITING
Nov 2020A Study of Adding Apalutamide to Radiotherapy and LHRH Agonist in High-Risk Patients With Hormone-Sensitive Prostate Cancer

Janssen Pharmaceutica N.V., Belgium — PHASE3

TrialACTIVE NOT RECRUITING

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

No FDA-approved treatments are currently listed for GRFoma.

1 clinical trialare actively recruiting — trials can provide access to cutting-edge therapies.

View clinical trials →

Clinical Trials

1 recruitingView all trials with filters →
Phase 21 trial
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)
Phase 2
Active Prior treatment eligible
· Sites: Birmingham, Alabama; Mobile, Alabama +18 more · Age: 1299 yrs

Specialists

2 foundView all specialists →
LM
Lawrence Engmann, MD
HARTFORD, CT
Specialist
PI on 3 active trials
GC
Global Clinical Compliance
Specialist
PI on 12 active trials

Treatment Centers

8 centers
⚗️ Trial Site

PCR Oncology

📍 Arroyo Grande, California

⚗️ Trial Site

City of Hope

📍 Duarte, California

⚗️ Trial Site

USC Norris Comprehensive Cancer Center

📍 Los Angeles, California

👤 Janssen Research & Development, LLC Clinical Trial

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

Travel Grants

No travel grants are currently matched to GRFoma.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about GRFoma

Disease timeline:

New recruiting trial: GnRHa + Letrozole in Non-obese Progestin-insensitive Endometrial Cancer and Atypical Hyperplasia Patients

A new clinical trial is recruiting patients for GRFoma

New recruiting trial: Study to Assess the Feasibility of Stopping Prostate Cancer Treatment Early in Elderly Patients

A new clinical trial is recruiting patients for GRFoma

New recruiting trial: Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer

A new clinical trial is recruiting patients for GRFoma

New recruiting trial: A Short-term Preoperative, Evaluating Activity and Safety of Elacestrant Monotherapy as Compared to Elacestrant + Ovarian Function Suppression (LHRH Agonist) in Premenopausal Patients With Stage I-II ER+/HER2- Breast Cancer

A new clinical trial is recruiting patients for GRFoma

New recruiting trial: GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients

A new clinical trial is recruiting patients for GRFoma

New recruiting trial: AMH as a Predictor of Infertility Risk in Children With Cancer (CHANCE)

A new clinical trial is recruiting patients for GRFoma

New recruiting trial: Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients

A new clinical trial is recruiting patients for GRFoma

New trial: Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Altera

Phase PHASE2 trial recruiting. nab-sirolimus

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about GRFoma

Are there clinical trials for GRFoma?

Yes — 1 recruiting clinical trial is currently listed for GRFoma on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat GRFoma?

2 specialists and care centers treating GRFoma are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.