Clinical trials for Glioblastoma
100 recruiting or active trials synced from ClinicalTrials.gov.
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Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing data- RECRUITINGPHASE1, PHASE2NCT07501559A Phase Ib/II Clinical Trial to Evaluate the Safety and Efficacy of JL15003 Injection in Patients With Recurrent Glioblastoma (rGBM)Jecho Biopharmaceuticals Co., Ltd.
- RECRUITINGPhase 2NCT07326566Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIIIBlack Diamond Therapeutics, Inc.
- RECRUITINGPhase 1NCT07464925A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade GliomaTetragon Biosciences Ltd
- RECRUITINGNCT07411690Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial TumorsMedical University of Warsaw · PI: Michal Senger, M.D.
- RECRUITINGPhase 1NCT07480941Dual-Targeting CAR-NK Cells for Recurrent/Progressive Glioblastoma and High-Grade GliomaBeijing Biotech
- RECRUITINGPhase 2NCT07225621Adjuvant Temozolomide ± 5-Aminolevulinic Acid + Low Intensity Diffuse Ultrasound Sonodynamic Therapy System for Newly Diagnosed GlioblastomaAlpheus Medical, Inc.
- RECRUITINGPHASE1, PHASE2NCT073912155G-PEARL: Paxalisib in Malignant Brain TumoursInstitute of Cancer Research, United Kingdom · PI: Juanita Lopez, MD, PhD
- RECRUITINGN/ANCT07426848OT SMILE: Occupational Therapy Group Intervention for Primary Brain Tumour PatientsRoyal College of Surgeons, Ireland
- ENROLLING BY INVITATIONNCT07417774Liquid Biopsy in Glioblastoma Treated With Chemoradiation and an Oxygen TherapeuticNuvOx LLC
- RECRUITINGN/ANCT06964815Silibinin in Association With Concomitant Chemoradiotherapy and Maintenance Temozolomide in STAT3 Positive IDH Wild-type, Newly Diagnosed Glioblastoma PatientsIstituto Oncologico Veneto IRCCS
- RECRUITINGPHASE1, PHASE2NCT07093814A Study of VRT106 for Injection in Patients With Recurrent/Progressive GlioblastomaGuangzhou Virotech Pharmaceutical Co., Ltd. · PI: Chengcheng Guo
- RECRUITINGEarly Phase 1NCT07076472Sonodynamic Therapy With SONALA-001 or 5-ALA HCL and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent GlioblastomaMayo Clinic · PI: Terence C. Burns, MD, PhD
- RECRUITINGPhase 2NCT07003542A Phase 2 and Pharmacodynamic Study of Sitagliptin in Patients With Progressive Grade 4 GliomasCase Comprehensive Cancer Center · PI: David Peereboom, MD
- RECRUITINGPhase 1NCT06917885CUE-102 in Recurrent GlioblastomaDavid Reardon, MD · PI: David Reardon, MD
- RECRUITINGPhase 1NCT07089641ERAS-801 for the Treatment of Resectable and Progressive or Recurrent IDH Wildtype Grade IV Glioblastoma or Astrocytoma With an EGFR Amplification or Mutation, ERAS801-SARG TrialJonsson Comprehensive Cancer Center · PI: Phioanh Nghiemphu, MD
- RECRUITINGPhase 1NCT07179328Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard ChemotherapySunnybrook Health Sciences Centre · PI: Nir Lipsman
- RECRUITINGN/ANCT06850766The Feasibility and Efficacy of Dose Timing (Morning vs Evening) of Temozolomide in the Treatment of GlioblastomaOttawa Hospital Research Institute · PI: Terry Ng, MD
- RECRUITINGPhase 2NCT06649851G-CSF After Chemo-radiation in Patients With GlioblastomaMassachusetts General Hospital · PI: Jorg Dietrich, MD, PhD
- RECRUITINGN/ANCT07144735Allogeneic γδT Cells in GlioblastomaPeking University Third Hospital
- RECRUITINGPhase 2NCT07193654Stupp Treatment With Intrathecal Injection of Thiotepa for Glioblastoma With Advanced SpreadSecond Affiliated Hospital, School of Medicine, Zhejiang University
- RECRUITINGEarly Phase 1NCT06552260A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type GlioblastomaUgonma Chukwueke · PI: Ugonma Chukwueke, MD
- RECRUITINGN/ANCT06797661Insights Into the Pathophysiology of Neurovascular Uncoupling in Patients with Brain Lesions.Erasme University Hospital · PI: Xavier De Tiège, MD,PhD
- RECRUITINGPhase 3NCT05439278Conventional Versus Hypofractionated Radiotherapy With Temozolomide in Elderly GlioblastomaSeverance Hospital · PI: Chan Woo Wee, MD, PhD
- RECRUITINGPhase 2NCT06936046Enhanced Adjuvant Therapy for Newly Diagnosed GBM With Partial Surgical Resection or Short-term ProgressionSecond Affiliated Hospital, School of Medicine, Zhejiang University
- RECRUITINGNCT06625684Key Longitudinal Associations With Risk and Glioblastoma OutcomesDuke University · PI: Quinn Ostrom, PhD
- RECRUITINGPHASE1, PHASE2NCT066302605G-RUBY: Avutometinib and Defactinib in Malignant Brain TumoursInstitute of Cancer Research, United Kingdom · PI: Juanita Lopez, MD, PhD
- RECRUITINGNCT06796335Development and Implementation of an Intervention Enhancing Involvement of Relatives to Patients With Acquired Brain Injury or Malignant Brain TumourRigshospitalet, Denmark
- RECRUITINGN/ANCT06975332Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) ProgressionMedical University of Warsaw · PI: Przemysław Kunert, Professor
- RECRUITINGPhase 1NCT066322365G-EMERALD: Amivantamab in Malignant Brain TumoursInstitute of Cancer Research, United Kingdom · PI: Juanita Lopez, MD, PhD
- RECRUITINGN/ANCT06222138Study of Biologic Tumor and Plasma Biomarkers of Response to TTFields in Patients Treated for Newly Diagnosed GlioblastomaInstitut Claudius Regaud
- RECRUITINGN/ANCT06512311Personalized Targeted Glioblastoma Therapies by ex Vivo Drug ScreeningMedical University of Vienna
- RECRUITINGPhase 1NCT06186401Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T CellsHideho Okada, MD, PhD · PI: Jennifer Clarke, MD, MPH
- RECRUITINGN/ANCT05768087Escalated Dose Proton Therapy Within the Multimodality Treatment of Glioblastoma PatientsUniversity of Aarhus · PI: Anouk K Trip, MD PhD
- RECRUITINGPhase 2NCT05871021Protective VEGF Inhibition for Isotoxic Dose Escalation in GlioblastomaUniversity Hospital Tuebingen · PI: Maximilian Niyazi, Prof. Dr.
- RECRUITINGN/ANCT06623565Extensive Resection of Malignant Brain Tumors Using Advanced Imaging TechniquesAmsterdam UMC, location VUmc
- ENROLLING BY INVITATIONPHASE1, PHASE2NCT06690216Evaluation of [18F]AlF-NOTA-PCP2 PET/CT for PD-L1 Detection in Malignant TumorsMan Hu · PI: Man Hu, Dr.
- RECRUITINGPhase 1NCT06418113Neoadjuvant Radio-chemotherapy Safety Pilot Study in Patients With GlioblastomaHospital San Carlos, Madrid
- RECRUITINGPHASE1, PHASE2NCT05736406A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of GlioblastomaHemerion Therapeutics · PI: Jan Drappatz, MD
- RECRUITINGPhase 1NCT06039709Sonodynamic Therapy in Patients With Recurrent GBMShayan Moosa, MD · PI: Shayan Moosa, MD
- ACTIVE NOT RECRUITINGN/ANCT06108206Adaptive Radiotherapy and MRIs Based on Patients With Newly Diagnosed High-Grade GliomaColumbia University · PI: Tony J. Wang, MD
- RECRUITINGPhase 2NCT06710249Impact of Salovum® and SPC® Flakes on Brain Tumor Induced EdemaPeter Siesjö
- RECRUITINGPhase 1NCT05917145ATM-Inhibitor WSD0628 in Combination With Radiation Therapy for Treatment of Recurrent High-Grade GliomaMayo Clinic · PI: William G. Breen, MD
- RECRUITINGNCT06924099TTFields General Routine Clinical Care in ndGBM Patients: a French Prospective Non-Interventional Study (TIGER France)NovoCure Ltd.
- RECRUITINGNCT06041555MRI Guided Radiotherapy and Radiobiological Data: the ISRAR Database (Irm Sequences for Radiobiological Adaptative Radiotherapy)Hospices Civils de Lyon
- RECRUITINGN/ANCT06183983Hitting the Mark: Introducing State-of-the-art MRI for Precision Radiotherapy of GlioblastomaErasmus Medical Center · PI: Alejandra Méndez Romero, MD, PhD
- RECRUITINGPhase 2NCT06220552The Efficacy and Safety of Low-dose Radiotherapy Combined With Sintilimab and Temozolomide in Recurrent GlioblastomaFifth Affiliated Hospital, Sun Yat-Sen University
- RECRUITINGPHASE1, PHASE2NCT07145047Clinical Study of Oncolytic Virus in GlioblastomaMianyang Central Hospital
- RECRUITINGN/ANCT06113705Imaging and Biological Markers for Prediction and Identification of Glioblastoma Pseudoprogression: a Prospective Study.Istituto Clinico Humanitas · PI: Letterio S Politi, MD
- RECRUITINGPhase 1NCT05577091Tris-CAR-T Cell Therapy for Recurrent GlioblastomaBeijing Tiantan Hospital · PI: Tao Jiang, Prof.
- RECRUITINGPhase 2NCT06058988Trastuzumab Deruxtecan (T-DXd) for People With Brain CancerMemorial Sloan Kettering Cancer Center · PI: Nelson Moss, MD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT05664243A Phase 1b / 2 Drug Resistant Immunotherapy With Activated, Gene Modified Allogeneic or Autologous γδ T Cells (DeltEx) in Combination With Maintenance Temozolomide in Subjects With Recurrent or Newly Diagnosed GlioblastomaIn8bio Inc. · PI: Louis B Nabors, MD
- RECRUITINGPHASE1, PHASE2NCT06059690Biologic Association Between Metabolic Magnetic Resonance-positron Emission Tomograph (MR-PET) and Tissue Measures of Glycolysis in Brain Tumors of Infiltrating Glioblastoma CellsJonsson Comprehensive Cancer Center · PI: Benjamin Ellingson, PhD
- ACTIVE NOT RECRUITINGPhase 1NCT05698199Study to Evaluate the Safety, Tolerability, Immunogenicity and Preliminary Efficacy of ITI-1001 In Patients With Newly Diagnosed Glioblastoma (GBM)Immunomic Therapeutics, Inc.
- RECRUITINGPhase 2NCT05909618Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain MetastasesSheba Medical Center · PI: Ronnie Shapira Frommer, Dr
- RECRUITINGPhase 1NCT05557292RMC-5552 Monotherapy in Adult Subjects With Recurrent GlioblastomaNicholas Butowski · PI: Nicholas Butowski, MD
- RECRUITINGPhase 1NCT05450744131I-TLX-101 for Treatment of Newly Diagnosed Glioblastoma (IPAX-2)Telix Pharmaceuticals (Innovations) Pty Limited
- RECRUITINGN/ANCT05720078UNIty-Based MR-Linac Guided Adaptive RadioThErapy for High GraDe Glioma-3 (UNITED-3)Sunnybrook Health Sciences Centre
- RECRUITINGPhase 1NCT05660369CARv3-TEAM-E T Cells in GlioblastomaMarcela V. Maus, M.D.,Ph.D. · PI: William Curry, MD
- ACTIVE NOT RECRUITINGPhase 2NCT04485949A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With GlioblastomaImvax
- RECRUITINGPHASE1, PHASE2NCT05768919Study of Liposomal Curcumin in Combination With RT and TMZ in Patients With Newly Diagnosed High-Grade GliomasSignPath Pharma, Inc. · PI: Matthias Holdhoff, MD
- RECRUITINGEarly Phase 1NCT05043701Individualized Systems Medicine Functional Profiling for Recurrent GlioblastomaOslo University Hospital · PI: Einar O. Vik-Mo, MD, PhD
- RECRUITINGPhase 2NCT05629702ARISTOCRAT: Blinded Trial of Temozolomide +/- CannabinoidsUniversity of Birmingham · PI: Fiona Collinson, MBBS, BSc, MRCP, FRCR, PhD
- RECRUITINGNCT06283927The RECSUR-study: Resection Versus Best Oncological Treatment for Recurrent Glioblastoma (ENCRAM 2302)Jasper Gerritsen · PI: Jasper Gerritsen, MD PhD
- RECRUITINGNCT06146738The PALSUR-study: Palliative Care Versus Surgery in High-grade Glioma Patients (ENCRAM 2203)Jasper Gerritsen · PI: Jasper Gerritsen, MD PhD
- RECRUITINGPHASE1, PHASE2NCT05664464Glutamate Inhibitors in GlioblastomaUniversity of Zurich · PI: Hans-Georg Wirsching, MD
- RECRUITINGNCT06273176The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent GlioblastomaErasmus Medical Center · PI: Jasper Gerritsen, MD PhD
- RECRUITINGNCT06146725The RESBIOP-study: Resection Versus Biopsy in High-grade Glioma Patients (ENCRAM 2202)Jasper Gerritsen · PI: Jasper Gerritsen, MD PhD
- RECRUITINGPhase 2NCT05565521UNITy-BasED MR-Linac Adaptive Simultaneous Integrated Hypofractionated Boost Trial for High Grade Glioma in the ElderlySunnybrook Health Sciences Centre
- RECRUITINGEarly Phase 1NCT05423210Atezolizumab and Pre-Surgical Brain Radiation Therapy for Glioblastoma MultiformeStony Brook University · PI: Alexander Stessin, MD
- ACTIVE NOT RECRUITINGPhase 2NCT04752813A Study of BPM31510 With Vitamin K1 in Subjects With Newly Diagnosed Glioblastoma (GB)BPGbio
- RECRUITINGPhase 1NCT05303467A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBMBoston Scientific Corporation · PI: Riad Salem, M.D.
- RECRUITINGN/ANCT05186064Glioblastoma Targeted Treatment Option Maximization by WGSUMC Utrecht
- ACTIVE NOT RECRUITINGN/ANCT05970757Physiological MRI for Precision Radiotherapy IDH-wildtype GlioblastomaErasmus Medical Center · PI: Patrick Tang, MSc
- RECRUITINGPhase 3NCT05271240Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBMNorthwell Health · PI: John Boockvar, MD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT04881032AGuIX Nanoparticles With Radiotherapy Plus Concomitant Temozolomide in the Treatment of Newly Diagnosed GlioblastomaCentre Jean Perrin · PI: Juliette Moreau, Md
- ACTIVE NOT RECRUITINGPhase 1NCT05241392Safety and Efficacy Study of Anti-B7-H3 CAR-T Cell Therapy for Recurrent GlioblastomaBeijing Tiantan Hospital · PI: Nan Ji, Dr.
- RECRUITINGNCT06118723The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)Jasper Gerritsen · PI: Jasper Gerritsen, MD PhD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT04019262Short Course Chemo-Radiation Therapy for Patients With Newly Diagnosed GlioblastomaJohn Flickinger · PI: John Flickinger, MD
- ACTIVE NOT RECRUITINGPhase 1NCT04573140A Study of RNA-lipid Particle (RNA-LP) Vaccines for Newly Diagnosed Pediatric High-Grade Gliomas (pHGG) and Adult Glioblastoma (GBM)University of Florida · PI: Elias Sayour, MD, PhD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT04910022Ph I/II Study of NMS-03305293+TMZ in Adult Patients With Recurrent GlioblastomaNerviano Medical Sciences
- ACTIVE NOT RECRUITINGPhase 2NCT03897491PD L 506 for Stereotactic Interstitial Photodynamic Therapy of Newly Diagnosed Supratentorial IDH Wild-type Glioblastomaphotonamic GmbH & Co. KG · PI: Walter Stummer, Prof. Dr.
- ACTIVE NOT RECRUITINGPhase 2NCT04762069A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma MultiformeCNS Pharmaceuticals, Inc. · PI: Sandra Silberman, MD, PhD
- RECRUITINGPhase 2NCT04523688Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumour Homogenate in GlioblastomaIstituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS · PI: Laura Ridolfi, DR
- RECRUITINGPhase 1NCT04541082Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsJazz Pharmaceuticals
- RECRUITINGPhase 1NCT04323046Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young AdultsSabine Mueller, MD, PhD · PI: Tom Davidson (tdavidson@chla.usc.edu), MD
- RECRUITINGPhase 1NCT04555577Peposertib and Radiation Therapy, Followed by Temozolomide for the Treatment of Patients With Newly Diagnosed MGMT Unmethylated Glioblastoma or GliosarcomaM.D. Anderson Cancer Center · PI: Nazanin Majd, MD
- ACTIVE NOT RECRUITINGPhase 2NCT04587830ADI-PEG 20 Plus Radiotherapy and Temozolomide in Subjects With Glioblastoma MultiformePolaris Group · PI: Kuo-Chen Wei, M.D.
- ACTIVE NOT RECRUITINGPhase 2NCT03688178DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without VarlilumabAnnick Desjardins, MD · PI: Annick Desjardins, MD, FRCPC
- ACTIVE NOT RECRUITINGPhase 1NCT04477200Mycophenolate Mofetil Combined With Radiation Therapy in GlioblastomaUniversity of Michigan Rogel Cancer Center · PI: Nathan Clarke, MD
- RECRUITINGN/ANCT02613988Advanced MR Imaging as Predictor of Treatment Response in Newly Diagnosed GlioblastomasAsan Medical Center · PI: Ho Sung Kim, MD, PhD
- ACTIVE NOT RECRUITINGPhase 1NCT04201873Pembrolizumab and a Vaccine (ATL-DC) for the Treatment of Surgically Accessible Recurrent GlioblastomaJonsson Comprehensive Cancer Center · PI: Timothy F Cloughesy
- ACTIVE NOT RECRUITINGPHASE2, PHASE3NCT04250922LAM561 With RT and TMZ for Adults With GlioblastomaLaminar Pharmaceuticals
- ACTIVE NOT RECRUITINGPhase 2NCT04049669Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPGTheodore S. Johnson · PI: Theodore S Johnson, MD, PhD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT04121455Glioblastoma Treatment With Irradiation and Olaptesed Pegol (NOX-A12) in MGMT Unmethylated PatientsTME Pharma AG
- RECRUITINGPHASE2, PHASE3NCT03970447A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent GlioblastomaGlobal Coalition for Adaptive Research · PI: Tim Cloughesy, MD
- RECRUITINGN/ANCT03144167Study of Prognostic Biomarkers of Survival at 6 Months for Patients Treated With Bevacizumab Glioblastomas in First Relapse After Failure of RadiochemotherapyCentre Hospitalier Universitaire, Amiens
- ACTIVE NOT RECRUITINGPhase 1NCT03749187BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV GliomasUniversity of California, San Francisco · PI: Sabine Mueller, MD, PhD
- ACTIVE NOT RECRUITINGPhase 2NCT03743662Nivolumab With Radiation Therapy and Bevacizumab for Recurrent MGMT Methylated GlioblastomaMemorial Sloan Kettering Cancer Center · PI: Christian Grommes, MD
- ACTIVE NOT RECRUITINGPHASE2, PHASE3NCT06105619A Study of PLB1001 Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN).Beijing Pearl Biotechnology Limited Liability Company · PI: Wenbin Li
- RECRUITINGPhase 1NCT03423628A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain CancerAstraZeneca · PI: Patrick Wen