Overview
Familial isolated clinodactyly of fingers is a condition where one or more fingers curve or bend sideways, most commonly affecting the fifth finger (pinky finger). The word 'clinodactyly' comes from Greek words meaning 'bent finger.' In this familial form, the condition runs in families and occurs on its own — meaning it is not part of a larger syndrome or associated with other birth differences. The curving is caused by an abnormally shaped bone (usually a wedge-shaped middle bone, called the middle phalanx) in the affected finger. The condition is present from birth and is usually noticed in infancy or early childhood as the hands grow. Most people with familial isolated clinodactyly have mild curving that does not cause pain or significant problems with hand function. The degree of bending can vary from barely noticeable to more pronounced. Both hands may be affected, or just one. Because this is an isolated finding, children with this condition typically develop normally in all other ways. Treatment is usually not needed for mild cases. If the curving is severe enough to interfere with hand function or grip, an orthopedic hand surgeon may recommend corrective surgery. Physical or occupational therapy may also be helpful in some cases. Overall, this is considered a benign condition with an excellent outlook, and most people live completely normal lives without any limitations.
Key symptoms:
Sideways curving of one or more fingersMost commonly affects the pinky (fifth) fingerCurving may affect one or both handsShortened or wedge-shaped finger boneFinger may appear crooked or angled inwardUsually painlessMild difficulty with fine grip in severe casesCosmetic concern about finger appearance
Autosomal dominant
Passed on from just one parent; each child has about a 50% chance of inheriting it
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for Familial isolated clinodactyly of fingers.
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Specialists
View all specialists →No specialists are currently listed for Familial isolated clinodactyly of fingers.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Familial isolated clinodactyly of fingers.
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Caregiver Resources
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Questions for your doctor
Bring these to your next appointment
- Q1.Is my child's clinodactyly truly isolated, or could it be part of a syndrome?,Should we get genetic testing to rule out other conditions?,How severe is the curving, and is it likely to get worse as my child grows?,Will my child need surgery, and if so, when is the best time?,Will this affect my child's ability to write, play sports, or play musical instruments?,What is the chance of passing this on to future children?,Should we see a hand specialist or occupational therapist?
Common questions about Familial isolated clinodactyly of fingers
What is Familial isolated clinodactyly of fingers?
Familial isolated clinodactyly of fingers is a condition where one or more fingers curve or bend sideways, most commonly affecting the fifth finger (pinky finger). The word 'clinodactyly' comes from Greek words meaning 'bent finger.' In this familial form, the condition runs in families and occurs on its own — meaning it is not part of a larger syndrome or associated with other birth differences. The curving is caused by an abnormally shaped bone (usually a wedge-shaped middle bone, called the middle phalanx) in the affected finger. The condition is present from birth and is usually noticed in
How is Familial isolated clinodactyly of fingers inherited?
Familial isolated clinodactyly of fingers follows a autosomal dominant inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does Familial isolated clinodactyly of fingers typically begin?
Typical onset of Familial isolated clinodactyly of fingers is neonatal. Age of onset can vary across affected individuals.