Familial cavitary optic disc anomaly

Last reviewed

🖨 Print for my doctorAdvocacy Hub →
ORPHA:464760OMIM:611543Q14.2
Who is this for?
Show terms as
8Treatment centers

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
Report missing data

Overview

Familial cavitary optic disc anomaly is a very rare inherited eye condition in which small cavities or hollow spaces form within the optic disc — the area at the back of the eye where the optic nerve connects to the retina. This condition runs in families and is typically passed from parent to child. The cavities in the optic disc can sometimes be seen during a routine eye exam using special imaging tools. People with this condition may not have any symptoms at all, or they may experience mild to moderate vision problems. In some cases, fluid can leak from the cavities into the layers of the retina, leading to a condition called serous macular detachment, which can cause blurred or distorted central vision. The severity of vision problems can vary widely, even among members of the same family. Because this condition is so rare, there is no specific cure or standard treatment protocol. Management focuses on monitoring the eyes regularly and treating complications like macular detachment if they arise. Treatment for fluid leakage may include observation, laser therapy, or other interventions depending on the severity. Early detection through family screening is important so that any vision-threatening complications can be caught and managed promptly.

Also known as:

Key symptoms:

Blurred central visionDistorted visionUnusual appearance of the optic disc on eye examFluid buildup under the retina (serous macular detachment)Reduced visual sharpness in one or both eyesGray or dark spots in the central field of visionNo symptoms at all in some affected individuals

Inheritance

Autosomal dominant

Passed on from just one parent; each child has about a 50% chance of inheriting it

Age of Onset

Variable

Can begin at different ages, from infancy through adulthood

Orphanet ↗OMIM ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for Familial cavitary optic disc anomaly.

View clinical trials →

No actively recruiting trials found for Familial cavitary optic disc anomaly at this time.

New trials open frequently. Follow this disease to get notified.

Search ClinicalTrials.gov ↗Join the Familial cavitary optic disc anomaly community →

No specialists are currently listed for Familial cavitary optic disc anomaly.

View NORD Rare Disease Centers ↗Undiagnosed Disease Network ↗

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Familial cavitary optic disc anomaly.

Search all travel grants →NORD Financial Assistance ↗

Community

Open Familial cavitary optic disc anomalyForum →

No community posts yet. Be the first to share your experience with Familial cavitary optic disc anomaly.

Start the conversation →

Latest news about Familial cavitary optic disc anomaly

No recent news articles for Familial cavitary optic disc anomaly.

Follow this condition to be notified when news becomes available.

Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.Does my eye exam show any fluid leakage or macular detachment?,How often should I have my eyes checked for changes?,Should my children or other family members be screened for this condition?,What symptoms should I watch for that would need urgent attention?,Are there any treatments available if my vision starts to get worse?,Is genetic testing available or recommended for my family?,Can you refer me to a retina specialist or neuro-ophthalmologist for further evaluation?

Common questions about Familial cavitary optic disc anomaly

What is Familial cavitary optic disc anomaly?

Familial cavitary optic disc anomaly is a very rare inherited eye condition in which small cavities or hollow spaces form within the optic disc — the area at the back of the eye where the optic nerve connects to the retina. This condition runs in families and is typically passed from parent to child. The cavities in the optic disc can sometimes be seen during a routine eye exam using special imaging tools. People with this condition may not have any symptoms at all, or they may experience mild to moderate vision problems. In some cases, fluid can leak from the cavities into the layers of the

How is Familial cavitary optic disc anomaly inherited?

Familial cavitary optic disc anomaly follows a autosomal dominant inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.