Endogenous Cushing syndrome

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ORPHA:641613
Who is this for?
Show terms as
2FDA treatments1Active trials27Specialists8Treatment centers1Financial resources

Where are you in your journey?

UniteRare data is sourced from FDA.gov, ClinicalTrials.gov, Orphanet, OMIM, and NORD.
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Overview

Also known as:

Orphanet ↗NORD ↗

FDA & Trial Timeline

3 events
Jul 2024A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement

University of Michigan

TrialRECRUITING
Dec 2021

Recorlev: FDA approved

Treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome for whom surgery is not an option or has not been curative

FDAcompleted
Feb 2012

Korlym: FDA approved

for the control of hyperglycemia secondary to hypercortisolism in adult patients with endogenous Cushing's syndrome who have type 2 diabetes mellitus or glucose intolerance and have failed surgery or are not candidates for surgery.

FDAcompleted

Data sourced from FDA regulatory filings and ClinicalTrials.gov. Updated periodically.

Treatments

2 available

Recorlev

levoketoconazole· Strongbridge Dublin Limited■ Boxed WarningOrphan Drug

Treatment of endogenous hypercortisolemia in adult patients with Cushing's syndrome for whom surgery is not an option or has not been curative

Korlym

mifepristone· Corcept Therapeutics, Inc.■ Boxed WarningOrphan Drug
for the control of hyperglycemia secondary to hypercortisolism in adult patients with endogenous Cushing's syndrome who have type 2 diabetes mellitus or glucose intolerance and have failed surgery or

for the control of hyperglycemia secondary to hypercortisolism in adult patients with endogenous Cushing's syndrome who have type 2 diabetes mellitus or glucose intolerance and have failed surgery or are not candidates for surgery.

Clinical Trials

1 recruitingView all trials with filters →
Other1 trial
A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement
Actively Recruiting
PI: Richard Auchus, MD, PhD (University of Michigan) · Sites: Ann Arbor, Michigan · Age: 1875 yrs

Specialists

Showing 25 of 27View all specialists →
CF
Chelsi Flippo
BETHESDA, MD
Specialist
1 Endogenous Cushing syndrome publication
RA
Richard J Auchus
ANN ARBOR, MI
Specialist
1 Endogenous Cushing syndrome publication
JF
James W Findling
MENOMONEE FALLS, WI
Specialist
1 Endogenous Cushing syndrome publication
TR
Thanitsara Rittiphairoj
Specialist
1 Endogenous Cushing syndrome publication
NC
Nipith Charoenngam
CAMBRIDGE, MA
Specialist
1 Endogenous Cushing syndrome publication
CT
Christina Tatsi
BETHESDA, MD
Specialist
1 Endogenous Cushing syndrome publication
PL
Padiporn Limumpornpetch
Specialist
1 Endogenous Cushing syndrome publication
AM
Ann W Morgan
Specialist
1 Endogenous Cushing syndrome publication
AT
Ana Tiganescu
Specialist
1 Endogenous Cushing syndrome publication
PB
Paul D Baxter
EVERETT, WA
Specialist
1 Endogenous Cushing syndrome publication
VN
Victoria Nyawira Nyaga
Specialist
1 Endogenous Cushing syndrome publication
MP
Mar Pujades-Rodriguez
Specialist
1 Endogenous Cushing syndrome publication
PS
Paul M Stewart
Specialist
1 Endogenous Cushing syndrome publication
RW
Rachel Wurth
SIOUX CITY, IA
Specialist
1 Endogenous Cushing syndrome publication
MR
Megan Rescigno
TOWSON, MD
Specialist
1 Endogenous Cushing syndrome publication
AM
Andreas Moraitis, MD
SUNNY ISLES BEACH, FL
Specialist
PI on 2 active trials
YP
Ying Ru, MD, PhD
Specialist
PI on 1 active trial
AM
Andreas G Moraitis, MD
SUNNY ISLES BEACH, FL
Specialist
PI on 2 active trials1 Endogenous Cushing syndrome publication
RP
Richard Auchus, MD, PhD
ANN ARBOR, MI
Specialist
PI on 1 active trial
CG
Coleman Gross
MCMINNVILLE, OR
Specialist
PI on 1 active trial20 Endogenous Cushing syndrome publications
CM
Coleman Gross, MD
MCMINNVILLE, OR
Specialist
PI on 2 active trials
FM
Fredric J Cohen, MD
Specialist
PI on 1 active trial
CM
Coleman Gross, M.D.
MCMINNVILLE, OR
Specialist
PI on 1 active trial
XM
Xavier Valencia, MD
DEERFIELD BEACH, FL
Specialist
PI on 1 active trial
MP
Martin Fassnacht, Professor
Specialist
PI on 1 active trial1 Endogenous Cushing syndrome publication

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Financial Resources

1 resources
Recorlev(levoketoconazole)Strongbridge Dublin Limited

Travel Grants

No travel grants are currently matched to Endogenous Cushing syndrome.

Search all travel grants →NORD Financial Assistance ↗

Community

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Latest news about Endogenous Cushing syndrome

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Caregiver Resources

NORD Caregiver Resources

Support, advocacy, and financial assistance for caregivers of rare disease patients.

Mental Health Support

Rare disease caregiving can be isolating. Connect with counseling and peer support.

Family & Caregiver Grants

Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Endogenous Cushing syndrome

Are there clinical trials for Endogenous Cushing syndrome?

Yes — 1 recruiting clinical trial is currently listed for Endogenous Cushing syndrome on UniteRare. See the clinical trials section on this page for phase, sponsor, and site details sourced from ClinicalTrials.gov.

Which specialists treat Endogenous Cushing syndrome?

25 specialists and care centers treating Endogenous Cushing syndrome are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.

What treatment and support options exist for Endogenous Cushing syndrome?

3 patient support programs are currently tracked on UniteRare for Endogenous Cushing syndrome. See the treatments and support programs sections for copay assistance, eligibility, and contact details.