Clinical trials for Drug- or toxin-induced pulmonary arterial hypertension
53 recruiting or active trials synced from ClinicalTrials.gov.
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Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing data- RECRUITINGPhase 1NCT06872112A Study Evaluating the Safety and Tolerability of Artesunate in Patients With Pulmonary Arterial HypertensionJoseph C. Wu · PI: Roham Zamanian, MD
- RECRUITINGPhase 2NCT06351345129 Xenon Imaging in Patients Treated With SotaterceptBastiaan Driehuys · PI: Sudarshan Rajagopal, MD, PhD
- RECRUITINGPhase 4NCT07140484Sotatercept in Pulmonary Arterial HypertensionUniversity of Alberta · PI: Jason Weatherald, MD
- RECRUITINGPhase 2NCT07175038A Study of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH) (ROCSTAR STUDY)AllRock Bio, Inc.
- RECRUITINGNCT07013149The Impact of ERA Switching on Risk Stratification in Pulmonary Arterial HypertensionUniversity of Sao Paulo General Hospital
- RECRUITINGNCT06998329PulmonAry hyperteNsion DiagnOsis: a National cohoRt reseArchUniversity of Sao Paulo General Hospital
- ENROLLING BY INVITATIONPhase 2NCT06992440Empagliflozin to Improve Right Ventricular Function in Pulmonary Arterial HypertensionGustavo A Heresi, MD, MS · PI: Gustavo Heresi, MD
- RECRUITINGN/ANCT06968962Comparison of Sequential to Initial Combination Therapy in PAHSecond Affiliated Hospital, School of Medicine, Zhejiang University
- RECRUITINGN/ANCT07457762AIRDROP: Can we Improve Adherence to Inhaled Treatment for Pulmonary Arterial Hypertension?University of Sao Paulo General Hospital
- RECRUITINGPhase 3NCT06941441PAH Exercise StudyUniversity of Washington · PI: Mary Beth Brown, PT, PhD
- RECRUITINGN/ANCT06804122Exercise-based Rehabilitation in Patients With Pulmonary Arterial HypertensionTampere Heart Hospital · PI: Jussi A Hernesniemi, MD PhD
- RECRUITINGN/ANCT06549452Mobile Health Intervention to Improve Exercise in Pediatric PHVanderbilt University Medical Center · PI: Eric Austin, MD
- RECRUITINGPHASE1, PHASE2NCT06649110A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)Novartis Pharmaceuticals
- RECRUITINGPhase 1NCT06554301A Study on the Efficacy and Safety of Empagliflozin in the Treatment of Pulmonary Arterial HypertensionChina National Center for Cardiovascular Diseases
- ACTIVE NOT RECRUITINGN/ANCT06543745Safety and Impact of Low Resistance Exercise Training on Quality of Life in Pulmonary Arterial HypertensionUniversity of Pennsylvania · PI: Nadine Al-Naamani, MD, MS
- RECRUITINGPhase 2NCT06104228129 Xenon MRI as a Biomarker for Diagnosis and Response to Therapy in Pulmonary Arterial Hypertension (PAH)Bastiaan Driehuys · PI: Fawaz Alenezi, MD
- ENROLLING BY INVITATIONNCT06445673A Prospective Non-interventional Observational Study to Observe Long-term Treatment and Outcomes in Pulmonary Arterial Hypertension (PAH) PatientsAOP Orphan Pharmaceuticals AG
- RECRUITINGPhase 3NCT06350032Investigational Trial to Evaluate Safety and Tolerability of Treprostinil in Children Diagnosed With PAHAOP Orphan Pharmaceuticals AG
- RECRUITINGNCT06567379Myocardial Work Evaluation in Patients With PAHCentral Hospital, Nancy, France
- RECRUITINGN/ANCT06569940Sleepiz One+ vs. Capnography and ElectrocardiographySleepiz AG · PI: Christian Neumann, Dr. med.
- RECRUITINGPHASE2, PHASE3NCT06683040Evaluation of the Efficacy and Safety of Oxacom® in Patients With Pulmonary Arterial HypertensionNational Medical Research Center for Cardiology, Ministry of Health of Russian Federation · PI: Tamila V Martynyuk, MD
- RECRUITINGNCT06454838Exercise Capacity Muscle Oxygenation and Arterial Stiffness in Children With Pulmonary Arterial HypertensionGazi University · PI: Meral BOŞNAK GÜÇLÜ, Prof. Dr.
- RECRUITINGNCT06476470Taiwan Interstitial Lung Disease Multi-center Investigation and RegistryTaichung Veterans General Hospital · PI: Pin-Kuei Fu, MD., Ph.D
- RECRUITINGPhase 2NCT06053580Repurposing Valsartan May Protect Against Pulmonary HypertensionUniversity of Washington · PI: Peter Leary, MD, PhD
- RECRUITINGPhase 4NCT06317805Initial Triple Therapy Including Parenteral Treprostinil vs Initial Double Oral Therapy in PAH Group I PatientsAOP Orphan Pharmaceuticals AG
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT06137742A Study to Learn About the Study Medicine Called PF-07868489 in Healthy Adult People and in People With Pulmonary Arterial HypertensionPfizer · PI: Pfizer CT.gov Call Center
- RECRUITINGPhase 2NCT04778046Pulmonary Hypertension SOLARBastiaan Driehuys · PI: Sudarshan Rajagopal, MD, PhD
- RECRUITINGPhase 3NCT05824923A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart FailurePulnovo Medical (Wuxi) Co., Ltd. · PI: Yaling Han
- RECRUITINGPhase 4NCT05825417Pulmonary Hypertension: Intensification and Personalisation of Combination RxSheffield Teaching Hospitals NHS Foundation Trust · PI: Alexander Rothman, MD / PhD
- ACTIVE NOT RECRUITINGPHASE2, PHASE3NCT05649748An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)Insmed Incorporated
- RECRUITINGPhase 2NCT05587712Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)Merck Sharp & Dohme LLC · PI: Medical Director
- ACTIVE NOT RECRUITINGNCT06582459Efficacy and Safety of High-Flow Nasal Cannula Versus Noninvasive Ventilation for Pulmonary Arterial Hypertension-Associated Acute Respiratory FailureThe First People's Hospital of Neijiang
- RECRUITINGNCT05665556REgistry of Pulmonary Arterial Hypertension Associated With CONNECTIVE Tissue Diseases (RECONNECTIVE)Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran · PI: Jose Luis Hernandez Oropeza, PhD
- RECRUITINGEarly Phase 1NCT05452889PET Image in PAH PatientsStephen Y. Chan · PI: Stephen Chan
- RECRUITINGNCT05566002Artificial Intelligence-assisted Evaluation of Pulmonary HYpertensionChinese Pulmonary Vascular Disease Research Group · PI: Zhihong Liu, MD, PhD
- RECRUITINGN/ANCT05413109COMPression of Left Main coRonary artEry in patientS With Pulmonary Arterial Hypertension aSymptomatIc fOr aNginaIRCCS Azienda Ospedaliero-Universitaria di Bologna · PI: Fabio Dardi, PhD, MD
- RECRUITINGNCT05368467National Registry and Cohort Study of Pulmonary Vascular DiseaseNanjing First Hospital, Nanjing Medical University
- ACTIVE NOT RECRUITINGPhase 2NCT04816604Open-label Extension Study of GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH)GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc. · PI: Richard Aranda
- ACTIVE NOT RECRUITINGPhase 3NCT04273945Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial HypertensionActelion · PI: Actelion Clinical Trials
- ACTIVE NOT RECRUITINGPhase 3NCT04175600A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial HypertensionActelion · PI: Actelion Clinical Trial
- ENROLLING BY INVITATIONPhase 3NCT03683186A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label ExtensionUnited Therapeutics
- RECRUITINGPhase 3NCT04062565Trial to Evaluate Parenteral Treprostinil and Riociguat on Right Ventriculo-vascular Coupling and Morphology in Those With Advanced PAHUniversity of Arizona · PI: Franz Rischard, DO
- ACTIVE NOT RECRUITINGPhase 2NCT03492177A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial HypertensionActelion · PI: Catherine Boisson
- RECRUITINGNCT06954727China Pulmonary Vascular Disease Intervention Diagnosis and Management Study-right Heart CatheterizationChina-Japan Friendship Hospital · PI: Zhenguo Zhai, PhD
- ACTIVE NOT RECRUITINGNCT03045029ADAPT - A Patient Registry of the Real-world Use of Orenitram®United Therapeutics
- ACTIVE NOT RECRUITINGNCT02980887Pulmonary Vascular Disease Phenomics Program PVDOMICSThe Cleveland Clinic · PI: Nicholas S Hill, MD
- RECRUITINGN/ANCT02691689Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt LesionsUniversitaire Ziekenhuizen KU Leuven · PI: Werner Budts, MD, PhD
- RECRUITINGNCT02249923Pediatric Pulmonary Hypertension Network (PPHNet) Informatics RegistryNew York Medical College · PI: Steven H Abman, MD
- RECRUITINGPhase 2NCT01712620Spironolactone for Pulmonary Arterial HypertensionNational Institutes of Health Clinical Center (CC) · PI: Michael A Solomon, M.D.
- RECRUITINGNCT01730092Natural History Study of Biomarkers in Pulmonary Arterial HypertensionNational Institutes of Health Clinical Center (CC) · PI: Michael A Solomon, M.D.
- ACTIVE NOT RECRUITINGN/ANCT01321073DelIVery for Pulmonary Arterial Hypertension (PAH) & Continued Support StudyMedtronic Cardiac Rhythm and Heart Failure · PI: DelIVery for PAH Clinical Research Specialist
- RECRUITINGPhase 1NCT02966665: Vascular Function in Health and DiseaseRussell Richardson · PI: Russell Richardson, Ph.D.
- RECRUITINGNCT01347216COMPERA / COMPERA-KIDSTechnische Universität Dresden · PI: Marius M Hoeper, MD, PhD