Clinical trials for Down syndrome

Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy

Effects of the Otago Exercise Program on Balance, Endurance, and Motor Coordination in Children With Down Syndrome

Oro-myofunctional Characteristics and Obstructive Sleep Apnea in Infants With Down Syndrome

HomeGrown: A Family-based Lifestyle Intervention to Support Healthy Development of Young Children With Down Syndrome

Endotype DIrected Treatment for OSA in Down Syndrome

Qualitative Effects of AEF0217 in Down Syndrome People

Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down Syndrome

AEF0217 in Participants With Down Syndrome

Effect of Cognitive-motor Training Versus Pilates Exercises on Postural Stability in Down Syndrome.

Effects of Jump Rope on Navicular Drop in Down Syndrome

Cervical Spine Abnormalities in Down Syndrome

Effects of Powerball in Children With Down Syndrome

Effects of Vojta Therapy on Functional Mobility and Gait Parameters in Children With Down Syndrome

Physical Fitness in DS: A Comparison of Cuevas Medak and Rebound Exercises

Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down Syndrome

The Effect of the HEP Approach in Infants With Down Syndrome

Evaluation of Fetal Bladder Emptying During the 11-14 Weeks' Ultrasound Examination as a Negative Predictive Marker for Chromosomal Abnormalities

Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down Syndrome

The Efficacy of Therapy in Patients With Acute Myeloid Leukemia and Down Syndrome in Russia

Immune Profile and Respiratory Parameters in Down Syndrome Children With Acute Pneumonia: Pre-Intervention Analysis

A VIRTUAL Three-month Intervention Study of the Effects of a Smartphone Application (HippoCamera) on Memory in Teens and Young Adults With Down Syndrome

Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological Samples

Effects of (tDCS) Combined With Virtual Reality Versus CPT on Brain, Cognitive, and GMS in Children With DS.

The Effects Of "Minds In Motion The Maze" on Balance and Gate In Children With Down Syndrome

Effects of Down Dog Yoga on Pre-writing Skills in Children With Down Syndrome

Nordic Walk on Balance and Functional Strength in Children With Down Syndrome

Measuring Aided Language Development

Optimizing the Management of OSA in Children With Down Syndrome

Sleep Intervention and Quality of Life in Down Syndrome

Relationship Between Eating Patterns, Body Composition and the Detection of Fatty Liver in Children and Adolescents With Trisomy 21: LiverTy Project

Aerobic Exercise With and Without Low Calorie Diet on Adiposity and BMI of Down Syndrome

Shared Book Reading to Promote Mental Well-being Among Young People with and Without Down's Syndrome

Pediatric Down Syndrome Post-Approval Study

Non-Invasive Brain Stimulation to Improve Language in Down Syndrome.

How Simplified Language Affects Comprehension and Learning in Young Children With Down Syndrome

Effects of High Intensity Interval Training in Down Syndrome

Effects of Pelvic Girdle Stabililty With Use of Therapeutic Taping in Down Syndrome

Brain Outcomes With Lifestyle Change in Down Syndrome

Swiss Ball Versus Frenkel Exercises Effects in Down Syndrome

Group-based Resistance Training for Adults With Down Syndrome

Suspension Therapy Effects on Mobility and Balance in Down Syndrome

Harness-based Mobility Intervention for Infants With Down Syndrome

Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography

Leucettinib-21 First-in-Human Phase 1 in Healthy Volunteers and Subjects With Down Syndrome and Alzheimer's Disease

Down Syndrome, Physical Activity and Sleep Apnea

Using Technologies to Promote HEalthy Lifestyles in Adolescents With Intellectual Disabilities

A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

The (Cost)Effectiveness of a Social Robot for Persons with Problems in Daily Structure and Planning in Disability Care

Down Syndrome Obstructive Sleep Apnea

Highest Dose of Uproleselan in Combination With Fludarabine and Cytarabine for Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Mixed Phenotype Acute Leukemia Relapsed or Refractory That Expresses E-selectin Ligand on the Cell Membrane

Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

Therapies for Down Syndrome Regression Disorder

Efficacy of Bumetanide to Improve Cognitive Functions in Down Syndrome

Genetic and Epigenetic Variations in Heterokaryotypic Monozygotic Twins Discordant for Down Syndrome

Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome

Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia

Genetic Markers and Biomarkers in Patients With Intellectual Disabilities of Genetic Origin

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

A Multicenter Retrospective Analysis of Postoperative Respiratory Complications in Children With Obstructive Sleepapnea

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Gamma Frequency Stimulation in Individuals With Down Syndrome

Transcranial Photobiomodulation With Near-Infrared Light for Language in Individuals With Down Syndrome

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

Effects of Hypoglossal Nerve Stimulation on Cognition and Language in Down Syndrome and Obstructive Sleep Apnea

Trial-Ready Cohort-Down Syndrome (TRC-DS)

PAP for Children With DS and OSAS

A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Evaluating Treatment of ADHD in Children with Down Syndrome

GnRH Therapy on Cognition in Down Syndrome

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Using Personal Mobile Technology to Identify Obstructive Sleep Apnea in Children With Down Syndrome (UPLOAD)

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

Validation of Sleep Questionnaires in the Down Syndrome Population

Evaluating Cognitive Outcomes in Down Syndrome

ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016

The Human Trisome Project

Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

DS-Connect®: The Down Syndrome Registry

Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome

Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma