Overview
Dislocation of the hip-dysmorphism syndrome is an extremely rare genetic condition that is present from birth. It is characterized by dislocation (displacement) of the hip joints along with distinctive facial and body features (dysmorphism). Affected individuals typically show hip instability or frank dislocation of one or both hips at birth, along with unusual facial features that may include a broad or flat face, a short nose, and other subtle differences in appearance. Additional skeletal abnormalities may be present, such as joint looseness (hyperlaxity), short stature, or other bone and joint problems. Some individuals may also have mild developmental delays or intellectual differences, though this varies from person to person. Because this syndrome is so rare, the medical understanding of it is limited. It was described in a small number of families, and the exact genetic cause has not been fully established. Treatment is mainly supportive and focuses on managing the hip dislocation through orthopedic interventions such as bracing, harnesses, or surgery, as well as addressing any other skeletal or developmental concerns. Early diagnosis and intervention by a team of specialists can help improve outcomes and quality of life. There is currently no cure for the underlying condition, so care is directed at treating symptoms and preventing complications.
Also known as:
Key symptoms:
Hip dislocation present at birthUnusual facial featuresShort statureLoose or overly flexible jointsBroad or flat faceShort noseSkeletal abnormalitiesPossible mild developmental delayLow muscle toneDifficulty walking or delayed walking
Clinical phenotype terms (20)— hover any for plain English
Autosomal recessive
Passed on when both parents carry the same gene change; often skips generations
Neonatal
Begins at or shortly after birth (first 4 weeks)
Treatments
No FDA-approved treatments are currently listed for Dislocation of the hip-dysmorphism syndrome.
View clinical trials →Clinical Trials
View all trials with filters →No actively recruiting trials found for Dislocation of the hip-dysmorphism syndrome at this time.
New trials open frequently. Follow this disease to get notified.
Specialists
View all specialists →No specialists are currently listed for Dislocation of the hip-dysmorphism syndrome.
Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Dislocation of the hip-dysmorphism syndrome.
Community
No community posts yet. Be the first to share your experience with Dislocation of the hip-dysmorphism syndrome.
Start the conversation →Latest news about Dislocation of the hip-dysmorphism syndrome
No recent news articles for Dislocation of the hip-dysmorphism syndrome.
Follow this condition to be notified when news becomes available.
Caregiver Resources
NORD Caregiver Resources
Support, advocacy, and financial assistance for caregivers of rare disease patients.
Mental Health Support
Rare disease caregiving can be isolating. Connect with counseling and peer support.
Family & Caregiver Grants
Financial assistance programs specifically for caregivers of rare disease patients.
Social Security Disability
Learn how rare disease patients may qualify for SSDI/SSI benefits.
Questions for your doctor
Bring these to your next appointment
- Q1.What is the severity of my child's hip dislocation, and what treatment approach do you recommend?,Should we pursue genetic testing, and what might it tell us?,What developmental milestones should I watch for, and when should I be concerned?,How often will my child need orthopedic follow-up and imaging?,Are there any physical activities my child should avoid?,What early intervention services should we start, and how do we access them?,What is the chance of this condition occurring again in future pregnancies?
Common questions about Dislocation of the hip-dysmorphism syndrome
What is Dislocation of the hip-dysmorphism syndrome?
Dislocation of the hip-dysmorphism syndrome is an extremely rare genetic condition that is present from birth. It is characterized by dislocation (displacement) of the hip joints along with distinctive facial and body features (dysmorphism). Affected individuals typically show hip instability or frank dislocation of one or both hips at birth, along with unusual facial features that may include a broad or flat face, a short nose, and other subtle differences in appearance. Additional skeletal abnormalities may be present, such as joint looseness (hyperlaxity), short stature, or other bone and j
How is Dislocation of the hip-dysmorphism syndrome inherited?
Dislocation of the hip-dysmorphism syndrome follows a autosomal recessive inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does Dislocation of the hip-dysmorphism syndrome typically begin?
Typical onset of Dislocation of the hip-dysmorphism syndrome is neonatal. Age of onset can vary across affected individuals.