Clinical trials for Diffuse intrinsic pontine glioma
28 recruiting or active trials synced from ClinicalTrials.gov.
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Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing data- RECRUITINGPhase 1NCT07076498Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care RadiationM.D. Anderson Cancer Center · PI: Gregory Kane Friedman Friedman, MD
- RECRUITINGPHASE1, PHASE2NCT07501156H3K27M-specific Immune Effector Cells Targeting DMG/DIPGShenzhen Geno-Immune Medical Institute
- RECRUITINGPhase 2NCT06838676ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade GliomasNationwide Children's Hospital · PI: David S. Ziegler, MD, FRACP
- RECRUITINGPhase 1NCT06305910CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young AdultsOX2 Therapeutics
- RECRUITINGPhase 1NCT06221553Safety and Efficacy of Loco-regional B7H3 IL-7Ra CAR T Cell in DIPGChulalongkorn University · PI: Piti Techavichit, MD
- RECRUITINGPhase 1NCT05544526CAR T Cells to Target GD2 for DMGUniversity College, London
- RECRUITINGPhase 1NCT05762419FUS Etoposide for DMGColumbia University · PI: Stergios Zacharoulis, MD
- ACTIVE NOT RECRUITINGPhase 1NCT05768880Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System TumorsSeattle Children's Hospital · PI: Rebecca Ronsley, MD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT05630209Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG)InSightec
- RECRUITINGPhase 1NCT05717699Oncolytic Virus Ad-TD-nsIL12 for Progressive Pediatric Diffuse Intrinsic Pontine GliomaCapital Medical University · PI: Hongwei Zhang, Prof.
- RECRUITINGPhase 1NCT05717712Oncolytic Virus Ad-TD-nsIL12 for Primary Pediatric Diffuse Intrinsic Pontine GliomaCapital Medical University · PI: Hongwei Zhang, Prof.
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT05615623Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPGInSightec
- RECRUITINGPhase 3NCT05476939Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication 2.0Gustave Roussy, Cancer Campus, Grand Paris · PI: Jacques GRILL, MD, PhD
- RECRUITINGPHASE1, PHASE2NCT05099003A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)National Cancer Institute (NCI) · PI: Adam L Green
- RECRUITINGPHASE1, PHASE2NCT04870944CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and LymphomaChildren's Oncology Group · PI: David S Ziegler
- RECRUITINGPhase 1NCT04943848rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMGAnn & Robert H Lurie Children's Hospital of Chicago · PI: Ashley Plant-Fox, MD
- RECRUITINGPhase 2NCT05009992Combination Therapy for the Treatment of Diffuse Midline GliomasUniversity of California, San Francisco · PI: Sabine Mueller, MD, PhD
- RECRUITINGPhase 2NCT05077735Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG StudyMayo Clinic · PI: Roman O. Kowalchuk, MD
- RECRUITINGPhase 1NCT04732065ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS TumorsSabine Mueller, MD, PhD · PI: Sabine Mueller, MD, PhD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT04758533Clinical Trial to Assess the Safety and Efficacy of AloCELYVIR With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) in Combination With Radiotherapy or Medulloblastoma in MonotherapyHospital Infantil Universitario Niño Jesús, Madrid, Spain · PI: Álvaro Lassaletta Atienza, MD
- RECRUITINGPhase 1NCT04196413GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG)Stanford University · PI: Michelle Monje
- RECRUITINGPhase 2NCT04250064A Study of Low Dose Bevacizumab With Conventional Radiotherapy Alone in Diffuse Intrinsic Pontine GliomaTata Memorial Centre · PI: Rahul Krishnatry, Dr
- RECRUITINGPhase 1NCT04099797C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)Baylor College of Medicine · PI: Jasia Mahdi, MD
- ACTIVE NOT RECRUITINGPhase 1NCT03598244Volitinib in Treating Patients With Recurrent or Refractory Primary CNS TumorsNational Cancer Institute (NCI) · PI: Ralph Salloum
- ACTIVE NOT RECRUITINGPhase 1NCT03605550A Phase 1b Study of PTC596 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma and High Grade GliomaNationwide Children's Hospital · PI: Maryam Fouladi, MD
- RECRUITINGNCT02417324International HIT-MED Registry (I-HIT-MED)Universitätsklinikum Hamburg-Eppendorf · PI: Stefan Rutkowski, Prof.
- RECRUITINGNCT03101813International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and RepositoryChildren's Hospital Medical Center, Cincinnati · PI: Lindsey Hoffman, DO
- RECRUITINGNCT01106794Molecular Analysis of Samples From Patients With Diffuse Intrinsic Pontine Glioma and Brainstem GliomaChildren's National Research Institute · PI: Javad Nazarian, PhD