Clinical trials for Diffuse cutaneous systemic sclerosis
88 recruiting or active trials synced from ClinicalTrials.gov.
ℹ
Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing data- RECRUITINGPHASE1, PHASE2NCT07473154Controlling Hyperactive Immunity With Long-lived LymphocytesQuell Therapeutics Limited
- RECRUITINGPHASE1, PHASE2NCT06947473Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.Beijing GoBroad Hospital
- RECRUITINGPhase 2NCT05029336Autologous Stem Cell Transplant (ASCT) for Autoimmune DiseasesStephan Grupp MD PhD · PI: Caitlin Elgarten, MD
- RECRUITINGPhase 2NCT07047690A Study of Nemolizumab for the Treatment of Adults With Systemic SclerosisGalderma R&D
- RECRUITINGPhase 2NCT07287670EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)Mediar Therapeutics
- RECRUITINGNCT07256418Transcriptomic Study of Cutaneous Fibroblasts in SclerodermaCentre Hospitalier Universitaire Dijon
- RECRUITINGPhase 1NCT07295847A Study of AZD0120 in Autoimmune DiseasesAstraZeneca
- RECRUITINGN/ANCT07292961Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With SclerodermaHacettepe University
- RECRUITINGN/ANCT07090226Diffuse Cutaneous Scleroderma (DSSc) SFDI StudyBoston University · PI: Andreea Bujor, MD, PhD
- RECRUITINGPhase 3NCT07245238Topical Cannabidiol Lotion for Pruritus Relief in SclerodermaKhon Kaen University
- RECRUITINGNCT07343115Familial Systemic SclerodermaUniversity Hospital, Strasbourg, France
- RECRUITINGNCT07183072Patients Diagnosed With Scleroderma: Physical Performance and FunctionalityHacettepe University
- RECRUITINGNCT07182968Cultural Adaptation, Validity, and Reliability of the Turkish Version of The PASTUL QuestionnaireHacettepe University
- RECRUITINGNCT07182981Patients Diagnosed With Scleroderma and Their Chewing and Swallowing PerformanceHacettepe University
- RECRUITINGPhase 2NCT06991114AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.Artiva Biotherapeutics, Inc. · PI: Michael Saddekni, M.D., PgDip, BCMAS
- ACTIVE NOT RECRUITINGNCT07080125A Study Using a Disease Registry to Observe the Long-term Effects of Nintedanib in People With Scleroderma-related Lung FibrosisBoehringer Ingelheim
- RECRUITINGNCT07491523Double Immunosuppression With or Without Anti-fibrotic in Scleroderma ILDUniversity of Patras
- RECRUITINGN/ANCT06256575Study of Diosmin for the Treatment of Digital Ulcers in Systemic SclerosisPrimus Pharmaceuticals · PI: Lukban
- ACTIVE NOT RECRUITINGN/ANCT06880627Brain Boost Program to Improve Cognitive Function in People With Systemic SclerosisUniversity of Michigan · PI: Yen Chen, PhD
- RECRUITINGN/ANCT06801119Efficacy and Safety of HN2301 in Autoimmune Diseases（AIDs）Shenzhen MagicRNA Biotechnology Co., Ltd · PI: Zhu Chen, MD
- RECRUITINGPhase 1NCT06925542A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune DiseaseCRISPR Therapeutics
- RECRUITINGPhase 1NCT06822881CT1190B in the Treatment of Patients With Moderate to Severe Refractory Systemic Lupus Erythematosus (SLE) or Refractory/Progressive Systemic Sclerosis (SSc)Beijing GoBroad Hospital
- RECRUITINGPhase 2NCT06843239Tibulizumab Systemic Sclerosis Understanding and Response Evaluation (TibuSURE)Zura Bio Inc · PI: Study Director
- RECRUITINGPhase 2NCT06375005Efficacy and Safety of Telitacicept in the Treatment of Systemic SclerosisSecond Affiliated Hospital, School of Medicine, Zhejiang University · PI: JING XUE, PhD
- ENROLLING BY INVITATIONNCT06472362Chest CT Biomarkers as Prognostic Predictors in SSc-ILDRoyal Brompton & Harefield NHS Foundation Trust · PI: Elisabetta A Renzoni
- RECRUITINGPhase 2NCT06655896Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Diffuse Cutaneous Systemic SclerosisNovartis Pharmaceuticals · PI: Novartis Pharmaceuticals
- RECRUITINGN/ANCT06182293Periodontal Microbiota in Systemic SclerosisUniversity Hospital, Strasbourg, France
- ENROLLING BY INVITATIONNCT06658483Hand ScleroDerma Lived Experience Scale in Individuals With Systemic SclerosisPamukkale University
- RECRUITINGPhase 2NCT06470048A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic SclerosisNovartis Pharmaceuticals · PI: Novartis Pharmaceuticals
- RECRUITINGPhase 1NCT06646913TENS in SclerodermaUniversity of Michigan
- RECRUITINGPhase 2NCT05785065Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung DiseaseCentre hospitalier de l'Université de Montréal (CHUM) · PI: Sabrina Hoa, MD
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT06400303KYSA-5: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic SclerosisKyverna Therapeutics · PI: MD
- ACTIVE NOT RECRUITINGN/ANCT06697561Development and Evaluation of an Evidence-based Education Program for People With Hand Dysfunction in SclerodermaWen-Shao Lin · PI: Cheng Hsin General Hospital
- RECRUITINGPHASE1, PHASE2NCT06328777RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic SclerosisCabaletta Bio · PI: Medical Director
- RECRUITINGNCT06598982Investigation of Respiratory Muscle Sarcopenia in Patients with Systemic SclerosisSelcuk University
- RECRUITINGN/ANCT06474910Connective Tissue Massage in SclerodermaFirat University
- RECRUITINGPhase 1NCT06414135Relmacabtagene Autoleucel for the Treatment of Systemic SclerosisLiangjing Lu · PI: Liangjing Lu
- RECRUITINGPhase 4NCT06546540The Safety and Efficacy of Telitacicept in the Treatment of Systemic SclerosisPeking University Third Hospital
- RECRUITINGNCT07012655Color Doppler Ultrasonography Evaluation of Abdominal and Peripheral Vasculopathy in Systemic Sclerosis PatientsAssiut University · PI: Sara Farrag, Lecturer
- RECRUITINGNCT06133244Hand Function Impairment in Systemic Sclerosis: Outcomes, Mechanisms and Experience (HANDSOME)UMC Utrecht
- RECRUITINGPhase 2NCT06195072Platform Clinical Study for Conquering SclerodermaScleroderma Research Foundation, Inc. · PI: Kevin O'Shea
- RECRUITINGN/ANCT05533034Personalized Home Respiratory Rehabilitation Program for Subjects With Systemic Sclerosis With Early Lung DiseaseAssistance Publique - Hôpitaux de Paris · PI: Camille DASTE, MD
- RECRUITINGPhase 2NCT06329401A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary FibrosisAvalyn Pharma Inc. · PI: Avalyn Pharma, Inc.
- ACTIVE NOT RECRUITINGN/ANCT06333795Faecal Microbiota Transplantation Against Chronic Diarrhea in Patients With Systemic SclerosisUniversity of Aarhus
- RECRUITINGN/ANCT05989763Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic SclerosisThe University of Texas Health Science Center, Houston · PI: Zsuzsanna H McMahan, MD, MHS (M-PI)
- RECRUITINGPhase 2NCT05149768Open Label Extension Study of Brentuximab Vedotin in Early dcSScLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · PI: Janet E Pope, PhD
- RECRUITINGPhase 3NCT06936215Safety and Efficacy of Baricitinib on Skin Tightening in Diffuse Cutaneous Systemic Sclerosis: A Comparative Study With MethotrexateBangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh · PI: Dr MD. Fahad Hossain, MBBS, MD
- RECRUITINGNCT06051773Evaluation of Muscle Involvement in Systemic SclerosisCentral Hospital, Nancy, France
- ACTIVE NOT RECRUITINGPhase 3NCT05925803Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY)AstraZeneca
- RECRUITINGPHASE1, PHASE2NCT06058091RY_SW01 Cell Injection Therapy in Systemic SclerosisJiangsu Renocell Biotech Company · PI: Jing Wang
- RECRUITINGPhase 1NCT05869955A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)Juno Therapeutics, Inc., a Bristol-Myers Squibb Company · PI: Bristol-Myers Squibb
- RECRUITINGPHASE2, PHASE3NCT05878717A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung DiseaseGlaxoSmithKline
- ENROLLING BY INVITATIONNCT06847750Elastography Ultrasound in Localized Scleroderma (Morphea) StudyThe Hospital for Sick Children
- ACTIVE NOT RECRUITINGN/ANCT05715463Rheumatology-based Adaptive Intervention for Social Determinants and Health EquityBrigham and Women's Hospital · PI: Candace H Feldman, MD, MPH, ScD
- ACTIVE NOT RECRUITINGN/ANCT05672992Longitudinal Spatial Frequency Domain Imaging StudyBoston University · PI: Andreea Bujor, MD, PhD
- RECRUITINGPhase 2NCT04789850Safety and Efficacy of Itacitinib in Adults With Systemic SclerosisAssistance Publique - Hôpitaux de Paris · PI: Luc Mouthon, MD-PhD
- RECRUITINGNCT05482607Evaluation of HRCT Patterns in Systemic Sclerosis-associated Interstitial Lung DiseaseCentral Hospital, Nancy, France · PI: Paul Decker, MD
- ACTIVE NOT RECRUITINGPhase 3NCT05726630Clinical Study of Divozilimab in Patients With Systemic SclerodermaBiocad
- RECRUITINGNCT05532865Prospective Cohort of Patients With Systemic Sclerosis at Brest University Hospital With BiobankingUniversity Hospital, Brest
- ACTIVE NOT RECRUITINGPhase 3NCT05198557A Study of MT-0551 in Patients With Systemic SclerosisTanabe Pharma Corporation · PI: General Manager
- RECRUITINGPhase 1NCT05016804Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell IV Infusion for Systemic SclerosisThe Foundation for Orthopaedics and Regenerative Medicine · PI: Chadwick Prodromos, MD
- RECRUITINGPHASE2, PHASE3NCT05098704Preventive Effect of Clopidogrel on the Systemic Sclerosis Development RiskUniversity Hospital, Bordeaux · PI: Marie-Elise TRUCHETET, Prof
- RECRUITINGNCT07345052Western Sweden Systemic Sclerosis ProjectSahlgrenska University Hospital
- RECRUITINGNCT05273138Analysis of Dermal Fibroblasts and Immune Cells During Systemic SclerosisUniversity Hospital, Lille · PI: David Launay, MD,PhD
- ACTIVE NOT RECRUITINGPhase 2NCT05270668Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (MK-7240-007)Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) · PI: Prometheus Biosciences
- ACTIVE NOT RECRUITINGPhase 4NCT05300932A Study Evaluating the Efficacy and Safety of Baricitinib in Systemic SclerosisTongji Hospital · PI: AIHUA DU
- ENROLLING BY INVITATIONNCT05108857PET Imaging of Systemic Sclerosis Using FDG and 68Ga-DOTA-Siglec-9Turku University Hospital · PI: Anne Roivainen
- RECRUITINGN/ANCT04917705Search for Diagnostic and Prognostic Biomarkers in Systemic Sclerosis and Inflammatory MyopathiesUniversity Hospital, Strasbourg, France
- RECRUITINGNCT04804930Trichoscopy and Systemic SclerodermaUniversity Hospital, Lille · PI: Vincent Sobanski, MD
- RECRUITINGPHASE1, PHASE2NCT03211793Mesenchymal Stromal Cells as Treatment for Digital Ulcers in Systemic SclerosisUMC Utrecht · PI: Marianne Verhaar, MD, PhD
- RECRUITINGPhase 2NCT04797286Sildenafil for Early Pulmonary Vascular Disease in SclerodermaJohns Hopkins University · PI: Stephen Mathai, MD
- RECRUITINGN/ANCT04627857Effect of the Use of Specific Oral Hygiene Devices on Gingival Health Among Patients With Systemic SclerosisUniversity Hospital, Strasbourg, France
- ACTIVE NOT RECRUITINGNCT04206644Systemic Sclerosis and Jak Inhibitors : Emphasis on MacrophagesRennes University Hospital · PI: Patrick JEGO
- RECRUITINGNCT04319120Pilot Study of Description of Cicatrisation Rates of Digital Ulcers in Systemic SclerodermaUniversity Hospital, Limoges
- ENROLLING BY INVITATIONN/ANCT04875078UVA-1 for Treatment of Skin Tightening and Improvement of Hand Function in SclerodermaUniversity of Utah
- RECRUITINGPhase 2NCT04356755Subcutaneous Injections of ASC to Heal Digital Ulcers in Patients With Scleroderma.University Hospital, Toulouse · PI: Grégory PUGNET, MD, PHD
- ACTIVE NOT RECRUITINGNCT04325217Post-marketing Surveillance on Long Term Use of Ofev Capsules in Systemic Scleroderma Associated Interstitial Lung Disease (SSc-ILD) in JapanBoehringer Ingelheim
- RECRUITINGNCT04095351Connective Tissue Diseases and Lung ManifestationsMedical University Innsbruck · PI: Judith Löffler-Ragg, Prof. MD
- RECRUITINGNCT04132206Longitudinal Characterization of Microbial Signature in Systemic Sclerosis PatientsHôpital Européen Marseille · PI: Chloé STAVRIS, MD
- RECRUITINGPhase 2NCT03844061Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic SclerosisHospital for Special Surgery, New York · PI: Robert Spiera, MD
- RECRUITINGPhase 2NCT03630211Autologous Stem Cell Transplantation in Patients With Systemic SclerosisPaul Szabolcs · PI: Paul Szabolcs, MD
- RECRUITINGNCT03473912Meir Medical Center Rheumatologic BiobankMeir Medical Center · PI: Yair Levy, Prof.
- RECRUITINGNCT03276923Maternal Autoimmune Disease Research Alliance (MADRA) RegistryDuke University · PI: Megan EB Clowse, MD, MPH
- RECRUITINGNCT03269630New Orleans Pulmonary Hypertension BiobankLouisiana State University Health Sciences Center in New Orleans
- ACTIVE NOT RECRUITINGPhase 2NCT02682511Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial HypertensionCumberland Pharmaceuticals · PI: Evan Brittain, MD
- RECRUITINGNCT01884051Hormonal, Metabolic, and Signaling Interactions in PAHVanderbilt University Medical Center · PI: James E Loyd, MD
- RECRUITINGNCT01776398Collection of Airway, Blood and/or Urine Specimens From Subjects for Research StudiesWeill Medical College of Cornell University · PI: Ronald G. Crystal, M.D.
- RECRUITINGNCT01656447Scleroderma Registry & Repository at the Hospital for Special SurgeryHospital for Special Surgery, New York · PI: Robert F Spiera, MD