Dental ankylosis

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1Specialists8Treatment centers

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Overview

Dental ankylosis is a rare oral condition in which the root of a tooth becomes directly fused to the surrounding alveolar bone, with the absence or obliteration of the periodontal ligament that normally separates tooth from bone. This fusion prevents normal tooth eruption and physiological movement, leading to the affected tooth becoming submerged or infraoccluded relative to adjacent teeth as the surrounding alveolar bone and neighboring teeth continue to grow. Dental ankylosis primarily affects the dental and skeletal systems of the oral cavity. It most commonly involves primary (deciduous) molars, though permanent teeth can also be affected. Key clinical features include failure of tooth eruption, progressive infraocclusion (the affected tooth appears to sink below the occlusal plane), a characteristic metallic or high-pitched percussion sound when tapped, tipping of adjacent teeth toward the ankylosed tooth, and potential disruption of the developing permanent successor tooth. The condition can occur as an isolated finding or may be associated with other dental anomalies. The exact cause of dental ankylosis is not fully understood, but it is thought to involve disruption of the periodontal ligament due to trauma, infection, local metabolic disturbances, or genetic predisposition. Some familial cases have been reported, suggesting a possible hereditary component in certain instances. When dental ankylosis occurs as part of a broader condition, it may be associated with other skeletal or dental developmental anomalies. Treatment depends on the severity of infraocclusion and the patient's age and dental development stage. Mild cases may be monitored over time, while moderate to severe cases may require extraction of the ankylosed tooth, often followed by space maintenance and orthodontic treatment to preserve proper alignment and occlusion. In some cases, decoronation (removal of the crown while leaving the root in place) is performed to preserve alveolar bone volume for future dental implant placement. Early diagnosis and management are important to prevent complications such as malocclusion, alveolar bone loss, and impaction of permanent successor teeth.

Also known as:

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Inheritance

Variable

Can be inherited in different ways depending on the underlying gene

Age of Onset

Childhood

Begins in childhood, roughly ages 1 to 12

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for Dental ankylosis.

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No actively recruiting trials found for Dental ankylosis at this time.

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Specialists

1 foundView all specialists →
WP
Wei Huang, DDS, PhD
Specialist
PI on 1 active trial

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Dental ankylosis.

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Community

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Latest news about Dental ankylosis

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Learn how rare disease patients may qualify for SSDI/SSI benefits.

Common questions about Dental ankylosis

What is Dental ankylosis?

Dental ankylosis is a rare oral condition in which the root of a tooth becomes directly fused to the surrounding alveolar bone, with the absence or obliteration of the periodontal ligament that normally separates tooth from bone. This fusion prevents normal tooth eruption and physiological movement, leading to the affected tooth becoming submerged or infraoccluded relative to adjacent teeth as the surrounding alveolar bone and neighboring teeth continue to grow. Dental ankylosis primarily affects the dental and skeletal systems of the oral cavity. It most commonly involves primary (deciduous)

At what age does Dental ankylosis typically begin?

Typical onset of Dental ankylosis is childhood. Age of onset can vary across affected individuals.

Which specialists treat Dental ankylosis?

1 specialists and care centers treating Dental ankylosis are listed on UniteRare, sourced from ClinicalTrials.gov principal investigators, published research, and the NPPES NPI registry.