Overview
Cystadenoma of childhood (Orphanet code 206470) is a rare benign ovarian tumor occurring in pediatric patients. As indicated by the ICD-10 code D27 (benign neoplasm of ovary), this condition involves the development of cystic, fluid-filled tumors within the ovary. Ovarian cystadenomas in childhood are uncommon, as these tumors are far more frequently encountered in adult women. They can be classified as serous or mucinous subtypes based on the type of epithelial lining and fluid content. The reproductive system is the primary body system affected. Clinically, children with ovarian cystadenomas may present with abdominal pain, abdominal distension or swelling, and a palpable abdominal or pelvic mass. In some cases, the tumor may be discovered incidentally during imaging for other reasons. Complications can include ovarian torsion, which may present as acute abdominal pain requiring emergency intervention. Hormonal disturbances are generally not a feature of these tumors, as cystadenomas are typically non-functional. Diagnosis is usually established through imaging studies such as ultrasound and confirmed by histopathological examination after surgical removal. The primary treatment is surgical excision, with ovary-sparing surgery (cystectomy) being the preferred approach in pediatric patients to preserve future fertility. The prognosis is generally excellent, as these tumors are benign with a very low risk of recurrence after complete surgical removal. Malignant transformation is exceedingly rare in the pediatric population.
Also known as:
Sporadic
Usually appears on its own, not inherited from a parent
Childhood
Begins in childhood, roughly ages 1 to 12
Treatments
No FDA-approved treatments are currently listed for Cystadenoma of childhood.
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Specialists
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Treatment Centers
8 centersBaylor College of Medicine Rare Disease Center ↗
Baylor College of Medicine
📍 Houston, TX
🏥 NORDStanford Medicine Rare Disease Center ↗
Stanford Medicine
📍 Stanford, CA
🔬 UDNNIH Clinical Center Undiagnosed Diseases Program ↗
National Institutes of Health
📍 Bethesda, MD
🔬 UDNUCLA UDN Clinical Site ↗
UCLA Health
📍 Los Angeles, CA
🔬 UDNBaylor College of Medicine UDN Clinical Site ↗
Baylor College of Medicine
📍 Houston, TX
🔬 UDNHarvard/MGH UDN Clinical Site ↗
Massachusetts General Hospital
📍 Boston, MA
🏥 NORDMayo Clinic Center for Individualized Medicine ↗
Mayo Clinic
📍 Rochester, MN
👤 Mayo Clinic Center for Individualized Medicine
🏥 NORDUCLA Rare Disease Day Program ↗
UCLA Health
📍 Los Angeles, CA
Travel Grants
No travel grants are currently matched to Cystadenoma of childhood.
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Common questions about Cystadenoma of childhood
What is Cystadenoma of childhood?
Cystadenoma of childhood (Orphanet code 206470) is a rare benign ovarian tumor occurring in pediatric patients. As indicated by the ICD-10 code D27 (benign neoplasm of ovary), this condition involves the development of cystic, fluid-filled tumors within the ovary. Ovarian cystadenomas in childhood are uncommon, as these tumors are far more frequently encountered in adult women. They can be classified as serous or mucinous subtypes based on the type of epithelial lining and fluid content. The reproductive system is the primary body system affected. Clinically, children with ovarian cystadenoma
How is Cystadenoma of childhood inherited?
Cystadenoma of childhood follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.
At what age does Cystadenoma of childhood typically begin?
Typical onset of Cystadenoma of childhood is childhood. Age of onset can vary across affected individuals.