Creeping myiasis

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Overview

Creeping myiasis, also known as cutaneous myiasis or larva migrans caused by fly larvae, is an infection of the skin caused by the larvae (maggots) of certain flies. The larvae burrow into the top layers of the skin and slowly move through the tissue, leaving a winding, snake-like trail that you can often see just beneath the skin surface. This trail is what gives the condition its name — 'creeping' refers to the way the larvae move under the skin over days or weeks. The most common flies responsible include species like Gasterophilus (horse botflies) and Hypoderma (cattle botflies), whose larvae accidentally infect humans. The condition is not caused by a genetic mutation — it is an infectious disease triggered by contact with fly larvae, usually in areas where these flies are common or where people have close contact with animals. Symptoms include intense itching, a visible moving track under the skin, redness, swelling, and sometimes small bumps or blisters along the trail. The condition is rarely life-threatening but can be very uncomfortable. Treatment is straightforward and usually involves antiparasitic medications such as ivermectin or albendazole, or in some cases, physical removal of the larvae. With proper treatment, most people recover fully.

Also known as:

Key symptoms:

Intense itching under the skinA visible winding or snake-like track just beneath the skin surfaceRedness and swelling along the trackSmall raised bumps or blisters near the moving trailA sensation of something moving under the skinSkin irritation that slowly moves from one area to another over daysOccasional pain or burning at the siteSwollen lymph nodes near the affected area in some casesSkin that looks inflamed or irritated along the trail path

Inheritance

Sporadic

Usually appears on its own, not inherited from a parent

Age of Onset

Variable

Can begin at different ages, from infancy through adulthood

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for Creeping myiasis.

View clinical trials →

No actively recruiting trials found for Creeping myiasis at this time.

New trials open frequently. Follow this disease to get notified.

Search ClinicalTrials.gov ↗Join the Creeping myiasis community →

No specialists are currently listed for Creeping myiasis.

View NORD Rare Disease Centers ↗Undiagnosed Disease Network ↗

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Creeping myiasis.

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Community

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Latest news about Creeping myiasis

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Caregiver Resources

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Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.Which medication do you recommend for my case — ivermectin or albendazole — and how long will I need to take it?,How will I know if the treatment is working? What changes should I look for in the skin track?,Is there any risk that the larvae have spread to deeper tissues or my eyes?,Do I need any follow-up blood tests or skin checks after treatment?,How did I get this infection, and how can I prevent it from happening again?,Are there any side effects from the antiparasitic medication I should watch out for?,Should other members of my household or travel companions be checked or treated?

Common questions about Creeping myiasis

What is Creeping myiasis?

Creeping myiasis, also known as cutaneous myiasis or larva migrans caused by fly larvae, is an infection of the skin caused by the larvae (maggots) of certain flies. The larvae burrow into the top layers of the skin and slowly move through the tissue, leaving a winding, snake-like trail that you can often see just beneath the skin surface. This trail is what gives the condition its name — 'creeping' refers to the way the larvae move under the skin over days or weeks. The most common flies responsible include species like Gasterophilus (horse botflies) and Hypoderma (cattle botflies), whose la

How is Creeping myiasis inherited?

Creeping myiasis follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.