Congenital urachal anomaly

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Overview

Congenital urachal anomaly is a condition present from birth that involves the urachus, a small tube-like structure that connects the bladder to the belly button (umbilicus) during fetal development. Normally, the urachus closes and becomes a solid cord (called the median umbilical ligament) before or shortly after birth. When this closure does not happen properly, it leads to a urachal anomaly. There are several types of urachal anomalies. A patent urachus means the entire tube stays open, allowing urine to leak from the belly button. A urachal cyst occurs when a pocket of fluid forms in the middle of the urachus. A urachal sinus is an opening at the belly button end, and a urachal diverticulum is an opening at the bladder end. Symptoms depend on the type and can include drainage or wetness at the belly button, infections, abdominal pain, or urinary problems. Many cases are found in newborns or infants, but some are not discovered until childhood or adulthood when complications like infection arise. Treatment usually involves surgery to remove the urachal remnant, especially if there are symptoms or recurrent infections. In uncomplicated cases, the outlook after surgery is excellent. Rarely, urachal remnants left untreated into adulthood can be associated with a type of bladder cancer called urachal carcinoma, though this is very uncommon.

Key symptoms:

Wetness or drainage from the belly buttonUrine leaking from the belly buttonRedness or swelling around the belly buttonBelly button infectionAbdominal pain, especially in the lower bellyA lump or mass felt below the belly buttonFever due to an infected cystFoul-smelling discharge from the belly buttonUrinary tract infectionsDifficulty with urinationDelayed healing of the umbilical cord stump in newborns

Inheritance

Sporadic

Usually appears on its own, not inherited from a parent

Age of Onset

Variable

Can begin at different ages, from infancy through adulthood

Orphanet ↗NORD ↗

Treatments

No FDA-approved treatments are currently listed for Congenital urachal anomaly.

View clinical trials →

No actively recruiting trials found for Congenital urachal anomaly at this time.

New trials open frequently. Follow this disease to get notified.

Search ClinicalTrials.gov ↗Join the Congenital urachal anomaly community →

No specialists are currently listed for Congenital urachal anomaly.

View NORD Rare Disease Centers ↗Undiagnosed Disease Network ↗

Treatment Centers

8 centers
🏥 NORD

Baylor College of Medicine Rare Disease Center

Baylor College of Medicine

📍 Houston, TX

🏥 NORD

Stanford Medicine Rare Disease Center

Stanford Medicine

📍 Stanford, CA

🔬 UDN

NIH Clinical Center Undiagnosed Diseases Program

National Institutes of Health

📍 Bethesda, MD

🔬 UDN

UCLA UDN Clinical Site

UCLA Health

📍 Los Angeles, CA

🔬 UDN

Baylor College of Medicine UDN Clinical Site

Baylor College of Medicine

📍 Houston, TX

🔬 UDN

Harvard/MGH UDN Clinical Site

Massachusetts General Hospital

📍 Boston, MA

🏥 NORD

Mayo Clinic Center for Individualized Medicine

Mayo Clinic

📍 Rochester, MN

👤 Mayo Clinic Center for Individualized Medicine

🏥 NORD

UCLA Rare Disease Day Program

UCLA Health

📍 Los Angeles, CA

Travel Grants

No travel grants are currently matched to Congenital urachal anomaly.

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Community

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Latest news about Congenital urachal anomaly

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Caregiver Resources

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Financial assistance programs specifically for caregivers of rare disease patients.

Social Security Disability

Learn how rare disease patients may qualify for SSDI/SSI benefits.

Questions for your doctor

Bring these to your next appointment

  • Q1.What type of urachal anomaly does my child (or do I) have?,Is surgery necessary, or can we safely monitor this condition?,What are the risks of surgery versus leaving the anomaly untreated?,Can the surgery be done using minimally invasive techniques?,How long is the expected recovery after surgery?,Is there any risk of this condition coming back after surgery?,Should we be concerned about any long-term complications, including cancer risk?

Common questions about Congenital urachal anomaly

What is Congenital urachal anomaly?

Congenital urachal anomaly is a condition present from birth that involves the urachus, a small tube-like structure that connects the bladder to the belly button (umbilicus) during fetal development. Normally, the urachus closes and becomes a solid cord (called the median umbilical ligament) before or shortly after birth. When this closure does not happen properly, it leads to a urachal anomaly. There are several types of urachal anomalies. A patent urachus means the entire tube stays open, allowing urine to leak from the belly button. A urachal cyst occurs when a pocket of fluid forms in the

How is Congenital urachal anomaly inherited?

Congenital urachal anomaly follows a sporadic inheritance pattern. Genetic counseling can help families understand recurrence risk and testing options.