Clinical trials for Chronic granulomatous disease
20 recruiting or active trials synced from ClinicalTrials.gov.
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Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing data- RECRUITINGPhase 2NCT07284641Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)Paul Szabolcs · PI: Paul Szabolcs, MD
- ENROLLING BY INVITATIONPhase 1NCT07113743Part B- G1X-CGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous DiseaseNational Institute of Allergy and Infectious Diseases (NIAID) · PI: Elizabeth M Kang, M.D.
- RECRUITINGPHASE1, PHASE2NCT06876363Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous DiseaseEnsoma
- RECRUITINGNCT06605378Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous DiseaseEnsoma
- ENROLLING BY INVITATIONPHASE1, PHASE2NCT06559176A Study of the Safety and Efficacy of Prime Editing (PM359) in Participants With p47phox Autosomal Recessive Chronic Granulomatous Disease (CGD )Prime Medicine, Inc.
- ENROLLING BY INVITATIONPHASE1, PHASE2NCT06253507pCCLCHIM-p47 (Lentiviral Vector Transduced CD34 Plus Cells) in Patients With p47 Autosomal Recessive Chronic Granulomatous Disease (AR-CGD)National Institute of Allergy and Infectious Diseases (NIAID) · PI: Elizabeth M Kang, M.D.
- RECRUITINGPhase 1NCT06325709Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous DiseaseNational Institute of Allergy and Infectious Diseases (NIAID) · PI: Suk S De Ravin, M.D.
- ACTIVE NOT RECRUITINGEarly Phase 1NCT05600907Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD)National Institute of Allergy and Infectious Diseases (NIAID) · PI: Elizabeth M Kang, M.D.
- ENROLLING BY INVITATIONPHASE1, PHASE2NCT05104723Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease With Inflammatory ComplicationsNational Institute of Allergy and Infectious Diseases (NIAID) · PI: Christa S Zerbe, M.D.
- RECRUITINGPHASE1, PHASE2NCT05333471Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated ColitisNational Institute of Allergy and Infectious Diseases (NIAID) · PI: Suchitra K Hourigan, M.D.
- RECRUITINGPhase 1NCT05189925NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)National Institute of Allergy and Infectious Diseases (NIAID) · PI: Suk S De Ravin, M.D.
- RECRUITINGPHASE1, PHASE2NCT05463133Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease (CGD) With an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined With Cytokine (IL-6, +/- IFN-gamma) AntagonistsNational Institute of Allergy and Infectious Diseases (NIAID) · PI: Elizabeth M Kang, M.D.
- ACTIVE NOT RECRUITINGEarly Phase 1NCT03910452Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant CyclophosphamideNational Institute of Allergy and Infectious Diseases (NIAID) · PI: Elizabeth M Kang, M.D.
- RECRUITINGN/ANCT03645486Lentiviral Gene Therapy for CGDShenzhen Geno-Immune Medical Institute
- RECRUITINGPHASE1, PHASE2NCT03167437An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With UstekinumabNational Institute of Allergy and Infectious Diseases (NIAID) · PI: Ivan J Fuss, M.D.
- ACTIVE NOT RECRUITINGPHASE1, PHASE2NCT02629120High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous DiseaseNational Institute of Allergy and Infectious Diseases (NIAID) · PI: Elizabeth M Kang, M.D.
- RECRUITINGPhase 2NCT03055247Combination of Ibuprofen, G-CSF and Plerixafor as Stem Cells Mobilization Regimen in Patients Affected by X-CGDIRCCS San Raffaele · PI: Fabio Ciceri, MD, PhD
- ACTIVE NOT RECRUITINGN/ANCT01652092Allogeneic Hematopoietic Stem Cell Transplant for Patients With Primary Immune DeficienciesMasonic Cancer Center, University of Minnesota · PI: Christen Ebens, MD
- RECRUITINGNCT00128973Evaluation of Patients With Immune Function AbnormalitiesNational Institute of Allergy and Infectious Diseases (NIAID) · PI: Harry L Malech, M.D.
- RECRUITINGN/ANCT00001405Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and GranulocytesNational Institute of Allergy and Infectious Diseases (NIAID) · PI: Harry L Malech, M.D.