Clinical trials for Cholangiocarcinoma
100 recruiting or active trials synced from ClinicalTrials.gov.
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Clinical trial records are synced from ClinicalTrials.gov through automated extraction.
Report missing data- RECRUITINGPhase 2NCT07478523FAPI-PET Value for the Initial Screening of Pancreatic and Biliary CancersUniversity Hospital, Bordeaux · PI: Charles Mesguich, Dr.
- RECRUITINGN/ANCT07476651Scout Dose of Resin MicrospheresSeoul National University Hospital
- RECRUITINGPhase 2NCT06728410A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or RearrangementMehmet Akce · PI: Mehmet Akce, MD
- RECRUITINGPhase 2NCT07201519Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion ChemotherapyMichael J Cavnar, MD · PI: Michael Cavnar, MD
- RECRUITINGPhase 2NCT07223307REGULUS: MRI-guided Adaptive SABR for Liver CancersStanford University
- RECRUITINGPhase 2NCT07260175Phase II Study Evaluating Ivosidenib Maintenance After SOC Adjuvant Chemotherapy in Curative mIDH1 CholangiocarcinomaInstitut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest · PI: Salah Al-Batran, Prof. Dr.
- RECRUITINGN/ANCT06735560Study Assessing PET Imaging With Zirconium-labelled Girentuximab in Patients With HCC, ICC or NENNantes University Hospital
- RECRUITINGN/ANCT07263217Mechanistic Study on the Protective and Regenerative Effects of Spirulina in Hepatectomy-Related Liver InjurySecond Affiliated Hospital, School of Medicine, Zhejiang University
- RECRUITINGNCT07206355In-Depth Characterisation of Biliary Strictures and Hepato-Pancreato-Biliary Focal Lesions for Development of New Technologies to Tackle Hepato-Pancreato-Biliary CancersUniversity of Nottingham · PI: Guruprasad P Aithal, MBBS, MD, PhD
- RECRUITINGN/ANCT06910722Liver Transplantation for Locally Advanced Intrahepatic Cholangiocarcinoma After SIRT and ChemotherapyAssistance Publique - Hôpitaux de Paris · PI: Mohamed Bouattour
- RECRUITINGPHASE1, PHASE2NCT07169734A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid TumorsAlentis Therapeutics AG
- RECRUITINGPhase 2NCT07070700Cryoablation Combined With Lenvatinib Plus QL1706 (Iparomlimab/Tuvonralimab) in Patients With Advanced Intrahepatic CholangiocarcinomaFudan University
- RECRUITINGPhase 2NCT06858735HYPERION CCA: a Phase 2 Trial of Systemic Therapy With or Without Liver-directed Radiation Therapy for Patients With Advanced Intrahepatic CholangiocarcinomaM.D. Anderson Cancer Center · PI: Eugene Koay, MD,PHD
- RECRUITINGPhase 2NCT07025174Sequential Anti-Angiogenic Therapy After Immunotherapy in Advanced Biliary Tract CancerFirst Affiliated Hospital of Zhejiang University · PI: Tingbo Liang, MD
- RECRUITINGNCT07530354A Longitudinal Cohort Study on the Changes of Physiological Mechanisms in Children After Biliary Tract ReconstructionWuhan Children's Hospital
- RECRUITINGNCT06864481Prospective Cohort of Immune Checkpoint Inhibitor-induced HepatitisUniversity Hospital, Montpellier
- RECRUITINGNCT06416397Diagnostic Approach for Cholangiocarcinoma Using Liquid Bile BiopsyUniversity Hospital, Bordeaux
- RECRUITINGN/ANCT06914648The Dragon PLC Trial (DRAGON-PLC)Maastricht University
- RECRUITINGN/ANCT06910670Implementing a Randomized Control Trial to Test the Expanded Web-based Decision AidWashington University School of Medicine · PI: Erin Linnenbringer, Ph.D., MS
- RECRUITINGNCT06862934Liver Transplantation for Unresectable Intrahepatic Colangiocarcinoma After Sustained Response to Neoadjuvant TreatmentsFondazione IRCCS Istituto Nazionale dei Tumori, Milano
- ENROLLING BY INVITATIONNCT06997913Adjuvant Immunotherapy Combined With ChemoRadiation for Patients With High-risk Resectable Extrahepatic Cholangiocarcinoma(AICRC)Hengchao Yu · PI: Lin Wang Professor.Wang, Doctor of Medicine(M.D.)
- RECRUITINGPhase 2NCT06859684Hepatic Arterial Infusion Chemotherapy (HAIC) Combined With Durvalumab and Lenvatinib in Patients With Locally Advanced or Metastatic Intrahepatic Cholangiocarcinoma: a Phase 2 Study(HAIC-quad Trial)West China Hospital
- RECRUITINGPhase 1NCT06723236A Study of MGC028 in Participants With Advanced Solid TumorsMacroGenics · PI: Pepi Pencheva, M.D.
- RECRUITINGPHASE1, PHASE2NCT06501625Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 MutationInstitut de Recherches Internationales Servier
- RECRUITINGPHASE2, PHASE3NCT06355427The Effect of [18F] F-FAPI PET-CT on Management in Patients With Proximal CholangiocarcinomaMara Veenstra, MD
- RECRUITINGPhase 2NCT06888063Additional Chemotherapy Administered Directly Into the Liver Using a Chemo Pump in Patients With Bile Duct Cancer Inside the Liver Treatable by SurgeryErasmus Medical Center · PI: Bas Groot Koerkamp, MD, PhD
- RECRUITINGPHASE1, PHASE2NCT06439485Phase I/II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 FusionM.D. Anderson Cancer Center · PI: Sunyoung Lee, MD,PHD
- RECRUITINGPhase 2NCT06664021Exploring the Efficacy and Safety of Tislelizumab in Combination With S-1 in the Treatment of Patients With Postoperative Recurrent High-risk Intrahepatic CholangiocarcinomaAnhui Provincial Hospital · PI: Lian-xin Liu
- RECRUITINGPhase 2NCT06721286Toripalimab Combined With Gemcitabine and Cisplatin (GemCis) as Preoperative Neoadjuvant Therapy for Resectable Intrahepatic CholangiocarcinomaTianjin Medical University Cancer Institute and Hospital
- RECRUITINGPhase 1NCT06546969Chemoimmunotherapy Combined With Hyperthermia and Spatially-Fractionated Radiotherapy in Advanced Biliary Tract CancerUniversity of Maryland, Baltimore · PI: Jason Molitoris, MD, PhD
- RECRUITINGPHASE1, PHASE2NCT06730009Phase I/II Study: Allogeneic NK-cell Therapy With Chemotherapy for Post-Surgery PDA or Cholangiocarcinoma PatientsMedigen Biotechnology Corporation · PI: Stanley Chang, PhD
- RECRUITINGNCT06607302Ivosidenib in Locally Advanced or Metastatic Cholangiocarcinoma With IDH1 R132 Mutation After at Least One Prior Systemic Treatment - an Observational StudyiOMEDICO AG
- RECRUITINGNCT06648057Investigation of Predictive Biomarkers in Patients With Advanced BTC Treated With Lenvatinib Plus PembrolizumabCHA University · PI: Hong Jae Chon, MD. PhD
- RECRUITINGPhase 2NCT06607276Phase 2 Trial of Adjuvant Adebrelimab Combined With Capecitabine in High-Risk Resected Cholangiocarcinoma: ACHIEVEThe First Affiliated Hospital with Nanjing Medical University
- RECRUITINGNCT06718257Chemotherapy Combined with Immunotherapy and Targeted Therapy in CholangiocarcinomaSecond Affiliated Hospital, School of Medicine, Zhejiang University · PI: Weilin Wang, PHD
- RECRUITINGPhase 2NCT06852287Phase II Clinical Study of GemOX Hepatic Arterial Infusion Combined with Lenvatinib and Toripalimab for Advanced and Unresectable Intrahepatic Cholangiocarcinoma and Gallbladder CancerTianjin Medical University Cancer Institute and Hospital
- RECRUITINGPhase 2NCT06438822Cadonilimab Combined With Liposomal Irinotecan Plus Leucovorin and Fluorouracil for Advanced CholangiocarcinomaWest China Hospital
- RECRUITINGNCT07101237An Exploratory Study on Developing an Integrated Approach Combining Multimodal Imaging and Multi-omics Characterization of Tumor Heterogeneity for Precision Diagnosis and Treatment Optimization in Liver Cancer.Peking Union Medical College Hospital
- RECRUITINGNCT07291063Anti-PD-1/PD-L1 Antibodies Plus Gemcitabine and Cisplatin for Advanced CCAShanghai Zhongshan Hospital
- RECRUITINGPhase 2NCT06050252Durvalumab With Gemcitabine and Cisplatin for the Treatment of High-Risk Resectable Liver Cancer Before SurgeryNational Cancer Institute (NCI) · PI: Hop S Tran Cao
- RECRUITINGNCT06505486GEMOX-HAIC Plus GEM-SYS in Combination With Lenvatinib and PD-1 Inhibitor for Large Unresectable ICCSun Yat-Sen Memorial Hospital of Sun Yat-Sen University · PI: Jia-yan Ni, M.D.
- RECRUITINGNCT06643208D-TACE-HAIC Combined With Envafolimab and Lenvatinib for Unresectable ICCFujian Provincial Hospital · PI: Maolin Yan, Doctor
- RECRUITINGPhase 2NCT05422690The Purpose of This Research Study is to See if Combining Gemcitabine, Cisplatin and Durvalumab Chemotherapy Treatments With a Direct Tumor Therapy Yittrium-90 (Y-90) Will Work Better Together to Shrink Tumors and Control CancerInova Health Care Services · PI: Arthur A. Winer, MD
- RECRUITINGPhase 2NCT06192797Combined HAIC, Lenvatinib and Pucotenlimab As Conversion Therapy for Unresectable Intrahepatic CholangiocarcinomaTongji Hospital · PI: Ze-yang Ding
- RECRUITINGN/ANCT06720883Robotically Assisted Surgery For Perihilar Cholangiocarcinoma: A Prospective StudyAzienda Ospedaliera di Padova · PI: Umberto Prof. Cillo, MD
- RECRUITINGPhase 1NCT06058663Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic CholangiocarcinomaMayo Clinic · PI: Umair Majeed, MD
- RECRUITINGN/ANCT05321992Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, ThailandMcMaster University · PI: Gina Agarwal, MBBS, PhD
- ENROLLING BY INVITATIONPhase 2NCT06963060Gem+Nab-P+LEN+TIS for Advanced Unresectable BTC (GALENT-BT)Wei Gong
- RECRUITINGPHASE1, PHASE2NCT05849480A Study of CDX-1140, a CD40 Agonist, in Combination With Capecitabine and Oxaliplatin (CAPOX) and Keytruda in Subjects With Biliary Tract Carcinoma (BTC)National Cancer Institute (NCI) · PI: Tim F Greten, M.D.
- ENROLLING BY INVITATIONNCT06474091Liquid Biopsy MonitORing Of CholangioCarcinOma for Treatment Response and Prognostic Outcomes (MOROCCO)Mayo Clinic · PI: Nguyen H. Tran, MD
- RECRUITINGPhase 2NCT06375915Precision Medicine in Patients With Unresectable CholAngiocarcinoma: RadioEmbolization and Combined Biological TherapyFrancesco De Cobelli
- RECRUITINGPhase 2NCT06298968Combined Therapy Using Gemcitabine and Cisplatin Chemotherapy, Lenvatinib and Adebrelimab for Patients With Advanced and Unresectable Intrahepatic CholangiocarcinomaNanfang Hospital, Southern Medical University · PI: Jinzhang Chen, MD
- ACTIVE NOT RECRUITINGPhase 2NCT06178445Efficacy and Safety of GemCis Plus Trastuzumab Plus Pembrolizumab in Previously Untreated HER2-positive Biliary Tract CancerInstitut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest · PI: Salah-Eddin Al-Batran, Prof. Dr.
- RECRUITINGN/ANCT06168292Intraductal Radiofrequency Thermoablation and Radiotherapy Combined Treatment for Extrahepatic CholangiocarcinomaNational Cancer Center, Korea · PI: Sang Myung Woo, M.D
- RECRUITINGN/ANCT06340620EUS Examination Using EndoSound Vision System vs. Standard EchoendoscopeOrlando Health, Inc. · PI: Ji Young Bang, MD MPH
- RECRUITINGPhase 2NCT06296563Perioperative Treatment of Resectable Intrahepatic Cholangiocarcinoma With the Combination of Adebrelimab and Apatinib and HAICLei ZHAO
- RECRUITINGNCT06277531Evaluation of diagnostiC Capacity of eccDNAs as Biomarkers in Indetermined biLiary Stricture(ECCBILE)Peking University Third Hospital · PI: Yonghui Huang
- RECRUITINGPhase 2NCT06313203HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT)Oslo University Hospital
- RECRUITINGPhase 2NCT05223816An Open-Label, Multiple-Center, Phase IIa/IIb Clinical Trial to Evaluate the Efficacy, Safety and Tolerability of VG161 as Monotherapy and in Combination With Nivolumab for Treatment of Patients With Hepatocellular Carcinoma or Intrahepatic CholangiocarcinomaVirogin Biotech Canada Ltd
- RECRUITINGPhase 2NCT06208462Neoadjuvant Therapy of HAIC(GEMOX) Combined With Adebrelimab and Lenvatinib for Resectable Intrahepatic Cholangiocarcinoma With High-risk Recurrence FactorsThe First Affiliated Hospital with Nanjing Medical University · PI: Feng Cheng, MD
- RECRUITINGPhase 2NCT05967182A Single-Arm Study of Pembrolizumab With Gemcitabine and Cisplatin as Perioperative Therapy for Potentially Resectable Intrahepatic CholangiocarcinomaM.D. Anderson Cancer Center · PI: Hop Tran Cao, MD
- RECRUITINGN/ANCT06098547LIver Transplantation for Non-Resectable Intrahepatic CholAngiocarcinoma (LIRICA)Azienda Sanitaria Ospedaliera · PI: Enrico Gringeri, Prof.
- RECRUITINGPhase 3NCT05948475Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in CholangiocarcinomaTransThera Sciences (Nanjing), Inc. · PI: Milind Javle, MD
- RECRUITINGNCT06140134Liver Transplantation in Intrahepatic CholangiocarcinomaRutgers, The State University of New Jersey · PI: Keri E Lunsford, MD, PhD
- ACTIVE NOT RECRUITINGPhase 2NCT06057571Study of TT-00420 (Tinengotinib) in Subjects With Cholangiocarcinoma Who Failed or Relapsed to Chemotherapy and FGFR InhibitorTransThera Sciences (Nanjing), Inc.
- ACTIVE NOT RECRUITINGNCT06707025The Expression of CD24 "do-not-eat-me" Signal in CholangiocarcinomaHadassah Medical Organization · PI: Tamar Hamburger
- ACTIVE NOT RECRUITINGPhase 2NCT06081829A Phase 2 Study of Ivosidenib in Previously Treated Japanese Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 MutationServier
- RECRUITINGPhase 1NCT06010862Clinical Study of CEA-targeted CAR-T Therapy for CEA-positive Advanced/Metastatic Malignant Solid TumorsChongqing Precision Biotech Co., Ltd · PI: Fei Li, M.D
- RECRUITINGPhase 3NCT05823311Lenvatinib, Tislelizumab Combined with Gemcitabine and Cisplatin (GPLET) in the Treatment of Advanced CholangiocarcinomaSecond Affiliated Hospital, School of Medicine, Zhejiang University
- RECRUITINGPHASE1, PHASE2NCT05874414Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated CholangiocarcinomaGenfit · PI: Peter Lichten, M.D.
- RECRUITINGPhase 2NCT05727176Study of Futibatinib in Patients With Advanced Cholangiocarcinoma With FGFR2 Fusion or RearrangementTaiho Oncology, Inc.
- RECRUITINGNCT06899854Collection of Blood and Tissue Samples From Patients With Primary Liver Cancer.Fondazione IRCCS Policlinico San Matteo di Pavia
- RECRUITINGPhase 3NCT05342194Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III StudyShanghai Junshi Bioscience Co., Ltd.
- RECRUITINGPhase 2NCT06335927HAIC Combined With Cadonilimab and Regorafenib as 2nd-line Treatment for ICCFudan University
- RECRUITINGPhase 2NCT05557578GOT Applied As Neoadjuvant Regimen for Patients of Resectable ICC with High-risk Factors of RecurrenceZhejiang Cancer Hospital · PI: Yuhua - Zhang, M.D.
- RECRUITINGPhase 3NCT05876754An Early Access Study of Ivosidenib in Patients With a Pretreated Locally Advanced or Metastatic CholangiocarcinomaServier Affaires Médicales
- RECRUITINGN/ANCT06729944Diagnostic Value of Next-Generation Sequencing Analysis in Biliary Tract TumoursIRCCS Azienda Ospedaliero-Universitaria di Bologna · PI: Francesco Vasuri, MD
- RECRUITINGPhase 1NCT05568680SynKIR-110 for Mesothelin Expressing Ovarian Cancer, Cholangiocarcinoma or MesotheliomaVerismo Therapeutics · PI: Laura Johnson, PhD
- RECRUITINGN/ANCT05957250[68Ga]Ga-FAPI-46 Positron Emission Tomography (PET) Scan to Improve the Imaging of Pancreatic and Bile Duct CancerAmsterdam UMC, location VUmc · PI: Rutger-Jan Swijnenburg, MD, PhD
- RECRUITINGPhase 2NCT05678270A Study of ICP-192 in Patients With FGFR2-Rearranged Unresectable or Metastatic Intrahepatic CholangiocarcinomaBeijing InnoCare Pharma Tech Co., Ltd. · PI: Jin Li
- RECRUITINGN/ANCT06340646Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)Washington University School of Medicine · PI: Graham Colditz, M.D., DrPH, MPH
- ACTIVE NOT RECRUITINGPhase 2NCT06239532HAIC Sequential TAE Combined With Tislelizumab and Surufatinib in Unresectable Intrahepatic CholangiocarcinomaQilu Hospital of Shandong University · PI: Zongli Zhang
- RECRUITINGPhase 1NCT05285358Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal MetastasesCity of Hope Medical Center · PI: Daneng Li, MD
- RECRUITINGPHASE2, PHASE3NCT05429697Study of SMT-NK Inj. Plus Pembrolizumab vs Pembrolizumab Monotherapy in Patients With Advanced Biliary Tract CancerSMT bio Co., Ltd. · PI: SEUNGWOO PARK
- RECRUITINGN/ANCT05053555High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver MalignanciesM.D. Anderson Cancer Center · PI: Joshua Kuban
- RECRUITINGPhase 2NCT06746480Clinical Study of VG161 in Advanced Intrahepatic CholangiocarcinomaCNBG-Virogin Biotech (Shanghai) Ltd. · PI: Tingbo Liang
- RECRUITINGPhase 1NCT04645160Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract CancersNational Cancer Institute (NCI) · PI: Jonathan M Hernandez, M.D.
- RECRUITINGPhase 2NCT05265208Selective Internal Radiation Therapy and Capecitabine (Chemotherapy) Treatment for Liver CancerCenter Eugene Marquis · PI: Julien Edeline, MD
- RECRUITINGN/ANCT05215665GEMOX Combined With Targeted Therapy and Immunotherapy for Patients With Advanced CholangiocarcinomaTianjin Medical University Cancer Institute and Hospital
- RECRUITINGNCT05187312Registry for Advanced EndoscopyRegion Stockholm · PI: Erik von Seth, MD, PhD
- ACTIVE NOT RECRUITINGNCT05210322Percutaneous Cholangiopancreatoscopy RegistryJohns Hopkins University · PI: Brian Holly, MD
- ACTIVE NOT RECRUITINGPhase 1NCT04708067Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic CholangiocarcinomaM.D. Anderson Cancer Center · PI: Eugene J Koay
- ACTIVE NOT RECRUITINGPhase 1NCT04491942Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial CancerNational Cancer Institute (NCI) · PI: Mamta Parikh
- RECRUITINGPhase 2NCT05010681Lenvatinib Plus Sintilimab in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Liver CancerFudan University · PI: Peng Wang, MD
- RECRUITINGNCT05714124Liver Embolization Approaches for Tumor ManagementIRCCS San Raffaele
- RECRUITINGPhase 2NCT04891289Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With SurgeryMemorial Sloan Kettering Cancer Center · PI: Andrea Cercek, MD
- ACTIVE NOT RECRUITINGPhase 2NCT04251715mFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic CholangiocarcinomaOHSU Knight Cancer Institute · PI: Skye C Mayo, MD, MPH
- RECRUITINGNCT04946773Deep Liver Phenotyping and Immunology StudyUniversity of Oxford · PI: Rory J Peters
- RECRUITINGNCT04753996Characterization of Biliary Cell-derived Organoids From Bile of PSC and Non-PSC PatientsMayo Clinic · PI: Konstantinos Lazaridis, MD
- ACTIVE NOT RECRUITINGN/ANCT04684862Infusion System for Hepatic CancerRonald DeMatteo, M.D.